Pilot Projects Program

试点项目计划

• 批准号: 10205091
• 负责人: Jane B. Lian
• 金额: $ 50.31万
• 依托单位: MAINEHEALTH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-03 至 2022-08-04
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10205091
• 关键词: Academic Medical Centers; Address; Applications Grants; Award; Basic Science; Biostatistics Core; Cardiovascular Diseases; Cardiovascular system; Clinical; Clinical Research; Clinical Research Protocols; Clinical Trials; Collaborations; Communities; Community Practice; Community Surveys; Custom; Development; Diabetes Mellitus; Discipline; Disease; Educational Activities; Epidemiology; Evaluation; Extramural Activities; Fostering; Funding; Goals; Grant; Group Meetings; Growth; Health; Healthcare; IACUC; Incentives; Institution; Institutional Review Boards; Intervention; Investigation; Laboratory Scientists; Leadership; Maine; Malignant Neoplasms; Manuscripts; Measures; Medical center; Methods; Mission; Monitor; New England; Obesity; Outcome; Patients; Performance; Physicians; Pilot Projects; Population; Practice based research; Preparation; Prevention; Problem Solving; Program Research Project Grants; Provider; Publications; Publishing; Research; Research Design; Research Personnel; Research Project Grants; Resources; Role; Rural; Rural Community; Rural Health; Rural Population; Scientist; Secure; Substance abuse problem; Sustainable Development; Technology; Training; Translational Research; Universities; Update; Vermont; Work; addiction; barrier to care; base; career development; catalyst; design; experience; health care delivery; improved; innovation; interdisciplinary collaboration; meetings; member; multidisciplinary; novel; patient oriented research; prevent; programs; recruit; rural area; rural dwellers; skills; success; training opportunity; translational approach; translational research program; translational study; web site

PROJECT SUMMARY The Pilot Project Program (PPP) of the NNE-CTR is a critical pipeline for clinical and translational research, and for investigators who will develop translational research programs that foster the multidirectional and transdisciplinary interactions necessary for patient-oriented research. The PPP is designed to stimulate new collaborations and multidisciplinary partnerships between researchers and rural clinicians, in order to address the disease-specific needs of the population of Northern New England. The PPP will emphasize collaborations and maximize interactions between Maine Medical Center (MMC) and University of Vermont (UVM) researchers and community- and rural-based clinicians to conduct research that will prevent and improve treatment of diseases that are prevalent in Northern New England. We will engage laboratory scientists, physician investigators and rural practitioners to collaborate on the investigation of cancer, cardiovascular and related diseases (e.g., obesity, diabetes) and substance abuse disorders, among others. This mission will be accomplished by the following specific aims: 1) Recruit investigators and facilitate the formation of interdisciplinary teams to conduct translational research addressing the health needs of the region. Research catalysts will provide guidance to rural practitioners and others new to the research endeavor. 2) Assure the success of the Pilot Project Program by providing investigators with the unique resources, skill sets and capabilities available through the NNE-CTR Cores, including “Studio sessions” with Key Component Activity (KCA) Directors, research catalysts, content experts, and community members to optimize study design and maximize study impact; access the educational activities of the Professional Development Core to build skills; provide “active surveillance” of ongoing pilot project studies to solve problems as they arise; and provide Scholar Awards for specific customized training opportunities in clinical and translational approaches to further enhance our investigators' success. 3) Continuously assess the “value added” by the Pilot Projects to the NNE-CTR using traditional and innovative metrics. PPP Directors will work with the NNE-CTR Leadership to evaluate success and further optimize our approach. Mixed methods results from the Tracking and Evaluation KCA will provide critical information necessary to refine our approach and assure that the PPP is providing the highest value to our community of investigators, clinicians and importantly to the residents of rural New England. Innovative findings from NNE-CTR pilot studies could develop into larger clinical studies and attract independent funding that could impact treatment paradigms.

项目概要 NNE-CTR 的试点项目计划 (PPP) 是临床和转化研究的重要渠道， 对于将开发转化研究计划以促进多向和 以患者为导向的研究所必需的跨学科互动。 PPP 旨在刺激新的 研究人员和农村临床医生之间的合作和多学科伙伴关系，以解决 新英格兰北部人口的疾病特定需求。 PPP将强调合作 并最大化缅因州医疗中心 (MMC) 和佛蒙特大学 (UVM) 之间的互动 研究人员以及社区和农村临床医生开展研究，以预防和改善 治疗新英格兰北部流行的疾病。我们将聘请实验室科学家， 医生调查员和农村从业者合作调查癌症、心血管和 相关疾病（例如肥胖、糖尿病）和药物滥用障碍等。此次任务将是 通过以下具体目标来实现： 1) 招募调查员并促进形成 跨学科团队进行转化研究，以满足该地区的健康需求。研究 催化剂将为农村从业者和其他新从事研究工作的人提供指导。 2) 确保 通过为研究人员提供独特的资源、技能组合和 通过 NNE-CTR 核心提供的功能，包括具有关键组件活动的“Studio 会话” (KCA) 董事、研究推动者、内容专家和社区成员优化研究设计和 最大化研究影响；参加专业发展核心的教育活动以培养技能； 对正在进行的试点项目研究提供“主动监督”，以解决出现的问题；并提供 授予临床和转化方法方面特定定制培训机会的学者奖，以进一步促进 提高我们调查人员的成功率。 3）持续评估试点项目给社会带来的“附加值” NNE-CTR 使用传统和创新指标。 PPP 董事将与 NNE-CTR 领导层合作， 评估成功并进一步优化我们的方法。跟踪和评估的混合方法结果 KCA 将提供完善我们的方法所需的关键信息，并确保 PPP 提供 对我们的研究人员、临床医生社区以及重要的新农村居民来说具有最高价值 英格兰。 NNE-CTR 试点研究的创新结果可以发展为更大规模的临床研究并吸引 可能影响治疗模式的独立资助。