Pilot Projects Program

项目总结 NNE-CTR的试点项目计划(PPP)是临床和转化性研究的关键管道， 对于将开发翻译研究项目的研究人员来说，这些项目将促进多方向和 以患者为中心的研究所需的跨学科互动。购买力平价旨在刺激新的 研究人员和农村临床医生之间的合作和多学科伙伴关系，以解决 新英格兰北部人口对疾病的特殊需求。PPP将强调合作 并最大化缅因州医疗中心(MMC)和佛蒙特州大学(UVM)之间的互动 研究人员和基于社区和农村的临床医生进行研究，以预防和改善 治疗新英格兰北部流行的疾病。我们将聘请实验室科学家， 医生调查人员和乡村医生合作调查癌症、心血管和 与之相关的疾病(如肥胖症、糖尿病)和药物滥用障碍等。这项任务将是 通过以下具体目标实现：1)招募调查人员并促进形成 跨学科团队进行转化性研究，以满足该地区的卫生需求。研究 催化剂将为农村从业者和其他新进入研究工作的人提供指导。2)保证 通过为调查人员提供独特的资源、技能和 通过NNE-CTR核心提供的功能，包括具有关键组件活动的“Studio Session” (KCA)主任、研究催化剂、内容专家和社区成员，以优化研究设计和 最大限度地发挥学习影响；接触专业发展核心的教育活动以培养技能； 对正在进行的试点项目研究提供“积极监督”，以便在出现问题时予以解决； 为临床和翻译方法的特定定制培训机会颁发学者奖，以进一步 提高我们的调查人员的成功率。3)持续评估试点项目对 使用传统和创新指标的NNE-CTR。PPP主管将与NNE-CTR领导层合作 评估成功并进一步优化我们的方法。跟踪和评估的混合方法结果 KCA将提供改进我们的方法所需的关键信息，并确保PPP提供 对我们社区的研究人员、临床医生，更重要的是对农村居民的最高价值 英国。NNE-CTR试点研究的创新发现可能会发展成更大规模的临床研究，并吸引 可能影响治疗模式的独立资金。

PROJECT SUMMARY The Pilot Project Program (PPP) of the NNE-CTR is a critical pipeline for clinical and translational research, and for investigators who will develop translational research programs that foster the multidirectional and transdisciplinary interactions necessary for patient-oriented research. The PPP is designed to stimulate new collaborations and multidisciplinary partnerships between researchers and rural clinicians, in order to address the disease-specific needs of the population of Northern New England. The PPP will emphasize collaborations and maximize interactions between Maine Medical Center (MMC) and University of Vermont (UVM) researchers and community- and rural-based clinicians to conduct research that will prevent and improve treatment of diseases that are prevalent in Northern New England. We will engage laboratory scientists, physician investigators and rural practitioners to collaborate on the investigation of cancer, cardiovascular and related diseases (e.g., obesity, diabetes) and substance abuse disorders, among others. This mission will be accomplished by the following specific aims: 1) Recruit investigators and facilitate the formation of interdisciplinary teams to conduct translational research addressing the health needs of the region. Research catalysts will provide guidance to rural practitioners and others new to the research endeavor. 2) Assure the success of the Pilot Project Program by providing investigators with the unique resources, skill sets and capabilities available through the NNE-CTR Cores, including “Studio sessions” with Key Component Activity (KCA) Directors, research catalysts, content experts, and community members to optimize study design and maximize study impact; access the educational activities of the Professional Development Core to build skills; provide “active surveillance” of ongoing pilot project studies to solve problems as they arise; and provide Scholar Awards for specific customized training opportunities in clinical and translational approaches to further enhance our investigators' success. 3) Continuously assess the “value added” by the Pilot Projects to the NNE-CTR using traditional and innovative metrics. PPP Directors will work with the NNE-CTR Leadership to evaluate success and further optimize our approach. Mixed methods results from the Tracking and Evaluation KCA will provide critical information necessary to refine our approach and assure that the PPP is providing the highest value to our community of investigators, clinicians and importantly to the residents of rural New England. Innovative findings from NNE-CTR pilot studies could develop into larger clinical studies and attract independent funding that could impact treatment paradigms.