Pilot Projects Program

项目摘要 NNE-CTR的试点项目计划（PPP）是临床和转化研究的关键管道， 和研究人员谁将开发转化研究计划，促进多方向， 以病人为导向的研究所需的跨学科互动。PPP旨在刺激新的 研究人员和农村临床医生之间的合作和多学科伙伴关系，以解决 北方新英格兰人口的疾病特异性需求。PPP将强调合作 并最大限度地发挥缅因州医学中心（MMC）和佛蒙特大学（UVM）之间的互动 研究人员和社区和农村为基础的临床医生进行研究，将预防和改善 治疗北方新英格兰流行的疾病。我们会让实验室的科学家， 医生调查人员和农村从业人员合作调查癌症，心血管和 相关疾病（例如，肥胖症、糖尿病）和药物滥用障碍等。这次使命 通过以下具体目标实现：1）招募调查员并促进 跨学科团队进行转化研究，以满足该地区的健康需求。研究 催化剂将为农村从业人员和其他新的研究工作提供指导。2)保证 通过为研究者提供独特的资源、技能组合和 通过NNE-CTR核心提供的功能，包括具有关键组件活动的"Studio会话" (KCA)董事，研究催化剂，内容专家和社区成员，以优化研究设计和 最大限度地提高学习效果;访问专业发展核心的教育活动，以培养技能; 对正在进行的试点项目研究进行"积极监督"，以解决出现的问题; 学者奖，用于临床和转化方法的特定定制培训机会，以进一步 提高我们调查人员的成功率3)不断评估试点项目对 NNE-CTR使用传统和创新的指标。PPP董事将与NNE-CTR领导层合作， 评估成功并进一步优化我们的方法。跟踪和评价的混合方法结果 KCA将提供必要的关键信息，以完善我们的方法，并确保PPP提供 最高的价值，我们的社区的调查人员，临床医生，重要的是农村居民的新 英格兰NNE-CTR试点研究的创新发现可以发展为更大的临床研究，并吸引 独立的资金，可能会影响治疗模式。

PROJECT SUMMARY The Pilot Project Program (PPP) of the NNE-CTR is a critical pipeline for clinical and translational research, and for investigators who will develop translational research programs that foster the multidirectional and transdisciplinary interactions necessary for patient-oriented research. The PPP is designed to stimulate new collaborations and multidisciplinary partnerships between researchers and rural clinicians, in order to address the disease-specific needs of the population of Northern New England. The PPP will emphasize collaborations and maximize interactions between Maine Medical Center (MMC) and University of Vermont (UVM) researchers and community- and rural-based clinicians to conduct research that will prevent and improve treatment of diseases that are prevalent in Northern New England. We will engage laboratory scientists, physician investigators and rural practitioners to collaborate on the investigation of cancer, cardiovascular and related diseases (e.g., obesity, diabetes) and substance abuse disorders, among others. This mission will be accomplished by the following specific aims: 1) Recruit investigators and facilitate the formation of interdisciplinary teams to conduct translational research addressing the health needs of the region. Research catalysts will provide guidance to rural practitioners and others new to the research endeavor. 2) Assure the success of the Pilot Project Program by providing investigators with the unique resources, skill sets and capabilities available through the NNE-CTR Cores, including “Studio sessions” with Key Component Activity (KCA) Directors, research catalysts, content experts, and community members to optimize study design and maximize study impact; access the educational activities of the Professional Development Core to build skills; provide “active surveillance” of ongoing pilot project studies to solve problems as they arise; and provide Scholar Awards for specific customized training opportunities in clinical and translational approaches to further enhance our investigators' success. 3) Continuously assess the “value added” by the Pilot Projects to the NNE-CTR using traditional and innovative metrics. PPP Directors will work with the NNE-CTR Leadership to evaluate success and further optimize our approach. Mixed methods results from the Tracking and Evaluation KCA will provide critical information necessary to refine our approach and assure that the PPP is providing the highest value to our community of investigators, clinicians and importantly to the residents of rural New England. Innovative findings from NNE-CTR pilot studies could develop into larger clinical studies and attract independent funding that could impact treatment paradigms.