Collaboration and Service

协作与服务 项目概要/摘要 我们已经确定了19个合作和服务项目的国家资源先进的核磁共振 技术BTRR.这一系列项目包括由NIH支持的令人印象深刻的项目组合。 他们也有所需的资源，在他们的家乡机构，使具有挑战性和生物医学相关 他们将收集样本并收集初步数据，以便为他们将在我们的设施中进行的实验提供信息。同样 重要的是，这些项目将受益于每个研发项目开发的独特技术。许多 的项目将使用在两个甚至三个研发领域开发的能力。这些项目都是 其特征在于明显需要提高灵敏度和分辨率，超越常规NMR所需的灵敏度和分辨率。 心理学可以提供。所有的C&S PI都有一个明确的愿景，即他们可以完成的任务， 超灵敏冷冻探针（TR&D1），动态核极化技术（TR&D2），以及 通过我们的用户程序提供串联混合（SCH）磁铁（TR&D3）。支持 在C&S项目中，我们有三个具体目标：1）帮助用户利用新技术 通过BTRR开发; 2）通过与用户的积极参与开发和完善技术 3）通过外展和积极招募新用户来扩大用户基础。C&S项目 被选中提供广泛的生物医学研究领域，可以从我们的BTRR受益。在 此外，他们当中很多人已积极使用我们的设施，这令我们充满信心 他们将真正发挥C&S项目的作用。

Collaboration and Service Project Summary/Abstract We have identified nineteen collaboration and service projects for the National Resource for Advanced NMR Technology BTRR. This set of projects encompasses an impressive portfolio of projects supported by the NIH. They also have the resources needed at their home institutions to make challenging and biomedically relevant samples and to gather preliminary data to inform the experiments they will undertake in our facility. Equally important, these projects will benefit from unique technologies developed in each of the TR&D projects. Many of the projects will use capabilities developed in two, or even three, of the TR&D areas. The projects are all distinguished by a clear need for improved sensitivity and resolution beyond what conventional NMR instru- mentation can provide. All the C&S PIs have a well-defined vision for what they can accomplish as the ultrasensitive cryoprobes (TR&D1), dynamic nuclear polarization technologies (TR&D2), and capabilities for the series connected hybrid (SCH) magnet (TR&D3) are made available through our user program. In support of the C&S projects we have three specific aims for the BTRR: 1) assist users in utilizing new technology developed through the BTRR; 2) develop and refine technology through active engagement with the user community; 3) broaden the user base through outreach and active recruitment of new users. C&S projects were selected to provide broad coverage of biomedical research areas which can benefit from our BTRR. In addition, many of them are already actively engaged users of our facilities, which gives us great confidence they will truly fill the role intended for C&S projects.