Project 1: Harmful algal bloom dynamics: assessing physiological and behavioral plasticity in natural populations
项目 1:有害藻华动态:评估自然种群的生理和行为可塑性
基本信息
- 批准号:10223307
- 负责人:
- 金额:$ 14.37万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-30 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:Arctic RegionsAreaBehaviorBehavioralCellsChillsClimateComplexCystDataDetectionDevelopmentDisease OutbreaksEcosystemEnvironmentEventExposure toFundingFutureGametogenesisGerminationGoalsGrowthHabitatsHealthHumanIn SituIndividualInvestigationKnowledgeLife Cycle StagesMaineMeasurementMicroscopeModelingNeeds AssessmentNutrientOceansOrganismParalysedParasitic infectionPatternPhysiologicalPhysiologyPhytoplanktonPoisoningPopulationPopulation DynamicsProcessProxyPublic HealthRecording of previous eventsSamplingShellfishSwimmingSyndromeSystemTechniquesTechnologyTemperatureTimeToxic effectToxinWood materialWorkbasebehavioral plasticitybehavioral responseclimate changecommunity engagementconditioningexposed human populationfuture climate scenarioharmful algal bloomsimprovedinsightknowledge basemigrationmortalitynovelprogramsresponsestem
项目摘要
Alexandrium fundyense and Pseudo-nitzschia spp. present expanding public health threats through their
associated poisoning syndromes, paralytic shellfish poisoning and amnesic shellfish poisoning. A major
concern is the extent to which these harmful algal blooms (HABs) and their human health impacts will be
altered by a changing climate. The Gulf of Maine is an ideal setting to explore this problem due to its long
history of A. fundyense investigations examining bloom physiology, toxicity, and bloom dynamics, leading to
construction of a robust population dynamics model. Nevertheless realistic forecasts under changing climate
conditions remain challenging for both A. fundyense and Pseudo-nitzschia, an emerging and less studied
threat. Current models for A. fundyense rely on culture-based characterizations of behavior that are not valid in
the natural environment, as demonstrated by novel in situ observations made during our prior WHCOHH
program. Life cycle processes, growth, grazing and mortality rates, and swimming patterns have all been
found to be significantly different in situ, making culture-based data inadequate for model assessments. A
second challenge stems from the adaptive potential of these taxa, whose physiologies vary substantially
across their ranges. This project's scientific premise is that our ability to assess and predict short- and long-
term responses of these HABs and their human health impacts to climate change requires characterization of
critical rates and behavioral patterns in natural populations, generated, whenever possible, through in situ
observations. Based on the new finding of a chilling requirement regulating the dormancy period of A.
fundyense cysts in the Nauset Marsh estuary, Aim 1 will assess plasticity of this response across multiple
habitats and populations and explore whether the temperature conditioning requirements of A. fundyense are
adaptive across its range. Aim 2 will use in situ technologies to determine relationships between temperature
and A. fundyense division, grazing, accumulation, and toxicity onset across a range of habitats. Previous
WHCOHH work discovered unexpectedly high accumulation and division rates for A. fundyense in Nauset
Marsh. If growth is similarly elevated across other habitats, incorporation of these rates into growing degree-
day and more complex, mechanistic models promise improved predictions of bloom timing and toxicity and
climate change assessments. Aim 3 will establish how cell concentration thresholds, parasite infections, and
migration shifts contribute to A. fundyense bloom termination. Aim 4 will greatly expand the knowledge base for
Pseudo-nitzschia bloom dynamics by combining previous and new in situ and lab-based observations.
Pseudo-nitzschia species composition is a first order predictor of toxicity, so knowledge of species diversity
and differences between species' physiology and life cycle dynamics is needed for toxicity predictions. In
summary, the project will provide the in situ assessments needed to develop and refine the bloom dynamics
models that underlie climate projections and estimates of human exposure to HAB toxins (Projects 2 and 3).
丰迪亚历山大藻和拟菱形藻。目前,公共卫生威胁不断扩大,
相关中毒综合征,麻痹性贝类中毒和失忆性贝类中毒。一个主要
令人担忧的是,这些有害藻华(HAB)及其对人类健康的影响将在多大程度上受到
因气候变化而改变缅因州海湾是探索这一问题的理想场所,因为它的长期
A的历史fundyense调查研究开花生理学,毒性和开花动力学,导致
建立一个强大的人口动态模型。然而,气候变化下的现实预测
条件仍然具有挑战性的两个A. fundyense和Pseudo-nitzschia,一种新兴的研究较少的
威胁目前的模型A. fundyense依赖于基于文化的行为特征,
自然环境,正如我们在之前的WHCOHH期间进行的新的原位观察所证明的那样
程序.生命周期过程、生长、放牧和死亡率以及游泳模式都已被
发现在原地有显着不同,使得基于文化的数据不足以进行模型评估。一
第二个挑战来自这些生物群的适应潜力,它们的生理变化很大
在他们的范围内。这个项目的科学前提是,我们评估和预测短期和长期的能力-
这些有害生物的长期反应及其对人类健康对气候变化的影响,需要确定以下特征:
在自然种群中的临界速率和行为模式,只要有可能,
意见。根据对冷量调节冬小麦休眠期的新发现,
Fundyense包囊在Nauset沼泽河口,目标1将评估这种反应的可塑性,在多个
栖息地和种群,并探讨是否A.芬迪恩斯群岛
适应范围广。目标2将使用原位技术来确定温度
和A. fundyense分裂,放牧,积累和毒性发作在一系列的栖息地。先前
WHCOHH的工作发现了A.瑙塞特地区的芬迪人
马什如果其他栖息地的生长率也同样升高,则将这些速率纳入生长度-
日和更复杂的,机械模型承诺改善预测水华的时间和毒性,
气候变化评估。目标3将确定细胞浓度阈值、寄生虫感染和
迁移的变化有助于A. Fundyense Bloom终止。目标4将大大扩展知识基础,
通过结合先前和新的现场和实验室观测研究拟菱形藻水华动力学。
拟菱形藻物种组成是毒性的一级预测因子,
毒性预测需要物种生理和生活史动力学之间的差异。在
总之,该项目将提供发展和完善水华动力学所需的现场评估
气候预测和人类接触有害藻华毒素估计所依据的模型(项目2和3)。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Donald M. Anderson其他文献
Paralytic shellfish toxins and seabirds: evaluating sublethal effects, behavioral responses, and ecological implications of saxitoxin ingestion by common murres (emUria aalge/em)
- DOI:
10.1016/j.hal.2025.102919 - 发表时间:
2025-09-01 - 期刊:
- 影响因子:4.500
- 作者:
Matthew M. Smith;Robert J. Dusek;Tuula Hollmen;Sarah K. Schoen;Caroline Van Hemert;Kristen Steinmetzer;Aidan Lee;Jenna Schlener;Vijay Patil;D. Ransom Hardison;David Kulis;Donald M. Anderson;Clark D. Ridge;Sherwood Hall - 通讯作者:
Sherwood Hall
Mesocosm study of PAC-modified clay effects on emKarenia brevis/em cells and toxins, chemical dynamics, and benthic invertebrate physiology
中宇宙研究聚铝改性黏土对海洋原甲藻细胞和毒素、化学动力学及底栖无脊椎动物生理学的影响
- DOI:
10.1016/j.hal.2024.102609 - 发表时间:
2024-04-01 - 期刊:
- 影响因子:4.500
- 作者:
Victoria M. Devillier;Emily R. Hall;Vince Lovko;Richard Pierce;Donald M. Anderson;Kristy A. Lewis - 通讯作者:
Kristy A. Lewis
Bowhead whale faeces link increasing algal toxins in the Arctic to ocean warming
弓头鲸粪便将北极藻类毒素的增加与海洋变暖联系起来
- DOI:
10.1038/s41586-025-09230-5 - 发表时间:
2025-07-09 - 期刊:
- 影响因子:48.500
- 作者:
Kathi A. Lefebvre;Patrick Charapata;Raphaela Stimmelmayr;Peigen Lin;Robert S. Pickart;Katherine A. Hubbard;Brian D. Bill;Gay Sheffield;Emily K. Bowers;Donald M. Anderson;Evangeline Fachon;Rick Thoman - 通讯作者:
Rick Thoman
Blooms of the toxic dinoflagellate, <em>Alexandrium fundyense</em> in the Casco Bay region of the western Gulf of Maine: Advection from offshore source populations and interactions with the Kennebec River plume
- DOI:
10.1016/j.dsr2.2005.06.017 - 发表时间:
2005-09-01 - 期刊:
- 影响因子:
- 作者:
Bruce A. Keafer;James H. Churchill;Donald M. Anderson - 通讯作者:
Donald M. Anderson
Donald M. Anderson的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Donald M. Anderson', 18)}}的其他基金
The 19th International Conference on Harmful Algae (ICHA) Mexico 2020
第十九届国际有害藻类会议 (ICHA) 墨西哥 2020
- 批准号:
10066778 - 财政年份:2020
- 资助金额:
$ 14.37万 - 项目类别:
Project 1: Harmful algal bloom dynamics: assessing physiological and behavioral plasticity in natural populations
项目 1:有害藻华动态:评估自然种群的生理和行为可塑性
- 批准号:
10434781 - 财政年份:2018
- 资助金额:
$ 14.37万 - 项目类别:
相似国自然基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
- 批准号:2021JJ40433
- 批准年份:2021
- 资助金额:0.0 万元
- 项目类别:省市级项目
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
- 批准号:32001603
- 批准年份:2020
- 资助金额:24.0 万元
- 项目类别:青年科学基金项目
AREA国际经济模型的移植.改进和应用
- 批准号:18870435
- 批准年份:1988
- 资助金额:2.0 万元
- 项目类别:面上项目
相似海外基金
Role of Central Neurotensin Signaling in the Ventral Tegmental Area for Ingestive Behavior and Body Weight
中枢神经降压素信号在腹侧被盖区对摄入行为和体重的作用
- 批准号:
10665597 - 财政年份:2022
- 资助金额:
$ 14.37万 - 项目类别:
Role of Central Neurotensin Signaling in the Ventral Tegmental Area for Ingestive Behavior and Body Weight
中枢神经降压素信号在腹侧被盖区对摄入行为和体重的作用
- 批准号:
10536558 - 财政年份:2022
- 资助金额:
$ 14.37万 - 项目类别:
Elucidation of the functional role of neural stem cells in the area postrema in the regulation of feeding behavior
阐明后区神经干细胞在调节摄食行为中的功能作用
- 批准号:
21K15177 - 财政年份:2021
- 资助金额:
$ 14.37万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Evaluation Analysis of Networked Compact City Considering the Wandering Behavior in the Urban Function and Residential guidance Area.
考虑城市功能与居住引导区游走行为的网络化紧凑城市评价分析。
- 批准号:
21K04296 - 财政年份:2021
- 资助金额:
$ 14.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
What is the origin of friction force depending on the sliding velocity? Approach from atomic-scale behavior in real area of contact
取决于滑动速度的摩擦力的来源是什么?
- 批准号:
20K04115 - 财政年份:2020
- 资助金额:
$ 14.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Defining the differential roles of Glutamatergic and GABAergic projections from the Lateral Preoptic Area to the Lateral Habenula in Reward, Aversion, and Drug-Seeking Behavior.
定义从外侧视前区到外侧缰核的谷氨酸能和 GABA 能投射在奖励、厌恶和药物寻求行为中的不同作用。
- 批准号:
10242872 - 财政年份:2019
- 资助金额:
$ 14.37万 - 项目类别:
Elucidating roles of ventral tegmental area dopaminergic neurons in motivation of appetitive goal-directed behavior
阐明腹侧被盖区多巴胺能神经元在食欲目标导向行为的激励中的作用
- 批准号:
19K03381 - 财政年份:2019
- 资助金额:
$ 14.37万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Defining the differential roles of Glutamatergic and GABAergic projections from the Lateral Preoptic Area to the Lateral Habenula in Reward, Aversion, and Drug-Seeking Behavior.
定义从外侧视前区到外侧缰核的谷氨酸能和 GABA 能投射在奖励、厌恶和药物寻求行为中的不同作用。
- 批准号:
9926602 - 财政年份:2019
- 资助金额:
$ 14.37万 - 项目类别:
Investigating the interplay between ventral tegmental area dopamine, medial orbitofrontal cortex, and ventromedial striatum in compulsive-like behavior
研究强迫样行为中腹侧被盖区多巴胺、内侧眶额皮质和腹内侧纹状体之间的相互作用
- 批准号:
9393053 - 财政年份:2018
- 资助金额:
$ 14.37万 - 项目类别:
Role of Lateral Hypothalmic Area Perineuronal Nets in the Reinstatement of Cocaine-Seeking Behavior
外侧下丘脑区神经周围网络在恢复可卡因寻求行为中的作用
- 批准号:
9598308 - 财政年份:2018
- 资助金额:
$ 14.37万 - 项目类别: