Institutional Career Development Core

机构职业发展核心

• 批准号: 10398853
• 负责人: Miriam Antoinette Bredella
• 金额: $ 136.37万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10398853
• 关键词: Academy; Address; Advisory Committees; Appointment; Award; Budgets; Clinical; Clinical Investigator; Clinical Research; Communities; Competence; Complex; Custom; Development; Disease; Diverse Workforce; Enrollment; Ensure; Environment; Faculty; Fellowship; Financial Support; Foundations; Funding; Future; Grant; Health; Individual; Industry; Institutes; K-Series Research Career Programs; Learning; Link; Longevity; Medical; Mentored Clinical Scientist Development Program; Mentors; Mentorship; Mission; Modeling; National Center for Advancing Translational Sciences; Peer Review; Performance; Positioning Attribute; Process; Program Development; Research; Research Methodology; Research Personnel; Resources; Risk; SECTM1 gene; Science; Special Population; Training; Training Support; Translational Research; United States National Institutes of Health; Universities; Work; base; career; career development; catalyst; community building; education research; faculty mentor; faculty support; human disease; improved; innovation; medical schools; next generation; programs; spelling; success; translational scientist

I. INSTITUTIONAL CAREER DEVELOPMENT CORE – KL2 PROGRAM: ABSTRACT The Harvard Catalyst (HC) KL2 Program is the cornerstone across Harvard University (HU) and its affiliated academic health centers (AHCs) to train the future leaders in clinical and translational research. The KL2 program admits, by a highly competitive process, CT investigators who are within the first 3 years of their initial faculty appointment at HU. Over the period of this award, to meet CTSA requirements and budget reductions, the HC KL2 program will admit 14 awardees in year 1, 13 awardees in year 2, 10 awardees in year 3, and will reach the 9 allowable slots by year 4. Each KL2 awardee will be enrolled for a period of two years to allow him/her to acquire by the end of the award period: 1) Subsequent peer-reviewed funding from the NIH or disease-specific foundation grants, and 2) Further support and acknowledgement at their AHCs as CT investigators who are critical to the institutional mission as documented by financial support and a clear track for promotion. These are the two key metrics of success of the HC KL2 program. To accomplish this, the KL2 program will create a community for junior CT investigators to enhance their transition to independence. The KL2 Program proposes four specific aims: (Aim 1) Select, mentor, and train HC KL2 trainees, and provide a supportive Harvard-wide environment that ensures their success, and develops and sustains a robust community of junior CT research investigators; (Aim 2) Optimize and individually tailor a customized educational program that supports the training of KL2 trainees so that they become independent, collaborative, and team science-based investigators committed to combating the most complex human diseases and health problems; (Aim 3) Evaluate and continuously improve individual and team mentorship models that support successful development and career progression of diverse HC KL2 trainees; and (Aim 4) Ensure that metrics of success are continually used to identify and improve components of the program that most effectively support career progression and transition of KL2 awardees to independence. These aims will be completed with the contributions of outstanding faculty mentors, HC Cores that enhance education and research methodology, and innovative HC programs that encourage team science and ensure a diverse workforce. KL2 graduates will become fully independent CT investigators capable of addressing unmet medical needs, and in turn, training the next generation of CT investigators.

I.机构职业发展核心-KL 2课程：摘要 哈佛催化剂（HC）KL 2计划是哈佛大学（HU）及其附属机构的基石。 学术健康中心（AHCs），培养未来的临床和转化研究的领导者。KL2 该计划承认，通过一个高度竞争的过程，CT调查人员谁是在第一个3年内，他们的初步 在胡教授的任命。在此期间，为了满足CTSA的要求和预算削减， HC KL 2计划将在第一年录取14名获奖者，第二年录取13名获奖者，第三年录取10名获奖者，并将 到第4年达到9个允许的插槽。 每名KL 2获奖者将注册两年，以便他/她在奖项结束时获得 期间：1）随后来自NIH或疾病特定基金会赠款的同行评审资金，以及2） 作为对机构至关重要的CT调查员，他们的AHC进一步支持和认可 使命，由财政支持和明确的晋升轨道记录。这是两个关键指标， HC KL 2计划的成功。为了实现这一目标，KL 2计划将为初级CT创建一个社区 调查人员加强向独立性的过渡。 KL 2计划提出了四个具体目标：（目标1）选择，指导和培训HC KL 2学员，并提供 一个支持性的哈佛全环境，确保他们的成功，发展和维持一个强大的 初级CT研究者社区;（目标2）优化和个性化定制 支持KL 2学员培训的教育计划，使他们成为独立，协作， 和团队科学为基础的研究人员致力于打击最复杂的人类疾病和健康 （目标3）评估并持续改进个人和团队指导模式， 不同HC KL 2学员的成功发展和职业发展;以及（目标4）确保 持续地使用成功的评估来识别和改进计划中最有效的组件， 支持职业发展和KL 2获奖者向独立过渡。这些目标将得以实现 与杰出的教师导师的贡献，HC核心，提高教育和研究 方法和创新的人力资源计划，鼓励团队科学和确保多元化的劳动力。KL2 毕业生将成为完全独立的CT调查员，能够解决未满足的医疗需求， 反过来，培训下一代CT研究人员。

项目成果

Association of Teaching Status and Mortality After Cancer Surgery.

• DOI: 10.1097/as9.0000000000000073
• 发表时间: 2021-09
• 期刊: Annals of surgery open : perspectives of surgical history, education, and clinical approaches
• 作者: Lam MB;Riley K;Mehtsun W;Phelan J;Orav EJ;Jha AK;Burke LG
• 通讯作者: Burke LG

Patterns of Recording Epileptic Spasms in an Electronic Seizure Diary Compared With Video-EEG and Historical Cohorts.

• DOI: 10.1016/j.pediatrneurol.2021.04.008
• 发表时间: 2021-09
• 期刊: PEDIATRIC NEUROLOGY
• 影响因子: 3.8
• 作者: LaGrant, Brian;Goldenholz, Daniel M.;Braun, Marvin;Moss, Robert E.;Grinspan, Zachary M.
• 通讯作者: Grinspan, Zachary M.

Focal Cooling for Drug-Resistant Epilepsy: A Review.

• DOI: 10.1001/jamaneurol.2022.1936
• 发表时间: 2022-09-01
• 期刊: JAMA NEUROLOGY
• 影响因子: 29
• 作者: Niesvizky-Kogan, Itamar;Bass, Michelle;Goldenholz, Shira R.;Goldenholz, Daniel M.
• 通讯作者: Goldenholz, Daniel M.

Prolonged fasting drives a program of metabolic inflammation in human adipose tissue.

• DOI: 10.1016/j.molmet.2020.101082
• 发表时间: 2020-12
• 期刊: Molecular metabolism
• 影响因子: 8.1
• 作者: Fazeli PK;Zhang Y;O'Keefe J;Pesaresi T;Lun M;Lawney B;Steinhauser ML
• 通讯作者: Steinhauser ML

Health Care Provider Perceptions of Caring for Individuals with Inherited Pancreatic Cancer Risk.

医疗保健提供者对照顾患有遗传性胰腺癌风险的个体的看法。

• DOI: 10.1007/s13187-019-01623-1
• 发表时间: 2020
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education
• 作者: Underhill,MeghanL;Pozzar,Rachel;Chung,Daniel;Sawhney,Mandeep;Yurgelun,Mathew
• 通讯作者: Yurgelun,Mathew