Advanced-Stage Development of a Geriatric Palliative Care Research Infrastructure

老年姑息治疗研究基础设施的高级开发

• 批准号: 10227194
• 负责人: MELISSA Diane ALDRIDGE
• 金额: $ 68.72万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10227194
• 关键词: Academy; Address; Aging; Alzheimer' s disease related dementia; Area; Caregivers; Caring; Categories; Cause of Death; Cessation of life; Chronic; Chronic Disease; Clinical; Collaborations; Communication; Communities; Community Networks; Complex; Consent; Data; Data Set; Dementia; Dependence; Development; Disease; Distress; Educational workshop; Elderly; Enrollment; Family; Family Caregiver; Fostering; Foundations; Funding; Generations; Grant; Grant Review; Health Services Research; Healthcare; Heart Diseases; High Prevalence; Improve Access; Infrastructure; Institution; Investments; K-Series Research Career Programs; Knowledge; Lead; Leadership; Longevity; Measures; Medical Education; Medicine; Mentorship; Morbidity - disease rate; National Institute on Aging; Network Infrastructure; Palliative Care; Patients; Persons; Philanthropic Fund; Physicians; Population; Population Growth; Population Research; Postdoctoral Fellow; Program Reviews; Public Health; Quality of life; Recommendation; Recording of previous events; Reporting; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Research Support; Research Training; Resources; Science; Scientist; Societies; Support System; Surveys; Talents; United States; United States National Institutes of Health; Work; Writing; age group; base; behavioral health; cancer risk; care systems; evidence base; experience; family support; frailty; human old age (65+); improved; interest; meetings; multiple chronic conditions; novel; physical symptom; population based; programs; psychological symptom; psychosocial; senior faculty; skills; support network; virtual; webinar

PROJECT SUMMARY Society is facing one of the largest public health challenges in its history - the growth of the population of older adults and increasing morbidity due to chronic serious illness. Over the next decades, most physicians will be caring for seriously ill older adults with physical and psychological symptom distress; progressive functional dependence and frailty; high family support needs; and escalating health care resource use. Indeed, the number of older adults with multiple chronic conditions is expected to increase by more than a third between 2000 and 2030 and those with dementia will nearly double. Abundant evidence suggests that the advanced stages of disease for most are characterized by inadequately treated physical distress; fragmented care systems; poor communication between doctors, patients, and families; and strains on family caregivers. The philanthropically funded National Palliative Care Research Center (NPCRC) has served as a collaborative mechanism for promoting interdisciplinary geriatric palliative care research since 2006. NPCRC was established to promote and develop palliative care research across the U.S. It addressed the National Academy of Medicine's recommendations to support a “cadre of experts whose numbers and talents are sufficient to: a) supply leadership for scientifically-based and practically useful medical education; and b) organize and conduct clinical, behavioral, and health services research for patients with serious and chronic illness.” The NPCRC, in collaboration with NIA, has established priorities for palliative care research, enhanced its evidence base, developed a new generation of researchers in palliative care, and created a national community of scientists. NPCRC has funded 100 interdisciplinary investigators (54 in aging research) from 46 institutions and 21 states along the continuum from junior to senior faculty and engaged in a broad spectrum of research dedicated to improving quality of life for persons living with serious illness. Our novel, research platform now forms the basis of our current R33 proposal to expand and enhance this research infrastructure. We will establish a new network of geriatric palliative care research trainees through collaboration across the palliative care focused post-doctoral programs in the U.S. For early-stage investigators, we will lead a research technical assistance program encompassing workshops and webinars on advanced statistical research methods, a grant writing (i.e., NIH K and R01 applications) skills workshop, and a grant review program. We will support new initiatives in dementia and population-based research and training. For experienced investigators, we will support the development and conduct of multisite collaborative geriatric palliative care research by supporting networking and project start-up meetings leading to multisite studies focusing on NIA research priorities in geriatric palliative care. Our proposal will advance research infrastructure that has successfully leveraged the NPCRC as the collaborative vehicle for interdisciplinary partnerships for geriatric palliative care research for trainees, junior, and experienced investigators across the U.S.

项目概要 社会正面临着历史上最大的公共卫生挑战之一——人口的增长 老年人和慢性严重疾病导致的发病率增加。在接下来的几十年里，大多数医生 将照顾患有身体和心理症状困扰的重病老年人；进步 功能依赖和虚弱；家庭支持需求高；并不断增加医疗保健资源的使用。的确， 患有多种慢性病的老年人数量预计将增加三分之一以上 2000 年至 2030 年间，痴呆症患者将增加近一倍。大量证据表明 对于大多数人来说，疾病晚期的特点是身体不适治疗不充分；支离破碎的 护理系统；医生、患者、家属之间沟通不畅；以及家庭照顾者的压力。 由慈善机构资助的国家姑息治疗研究中心 (NPCCRC) 已成为 自2006年起促进跨学科老年姑息治疗研究的协作机制。NPCRC 成立的目的是在美国范围内促进和发展姑息治疗研究。 医学科学院建议支持“数量和人才均符合要求的专家骨干队伍” 足以： a) 为基于科学且实用的医学教育提供领导；和 b) 为严重和慢性疾病患者组织和开展临床、行为和健康服务研究 疾病。” NPCCRC 与 NIA 合作，确定了姑息治疗研究的优先事项，加强了 其证据基础，培养了新一代姑息治疗研究人员，并创建了国家 科学家社区。 NPCCRC 资助了来自 46 个国家的 100 名跨学科研究人员（其中 54 名从事老龄化研究） 机构和 21 个州，从初级到高级教师，从事广泛的研究 致力于改善严重疾病患者的生活质量的研究。 我们新颖的研究平台现在构成了我们当前 R33 提案的基础，以扩展和增强这一点 研究基础设施。我们将通过以下方式建立一个新的老年姑息治疗研究实习生网络 美国以姑息治疗为重点的博士后项目之间的合作 调查人员，我们将领导一项研究技术援助计划，包括以下方面的研讨会和网络研讨会 先进的统计研究方法、资助写作（即 NIH K 和 R01 申请）技能研讨会以及 拨款审查计划。我们将支持痴呆症和基于人群的研究和培训方面的新举措。 对于经验丰富的研究人员，我们将支持多地点协作老年病学的开发和实施 通过支持网络和项目启动会议进行姑息治疗研究，从而进行多地点研究 重点关注 NIA 在老年姑息治疗方面的研究重点。我们的提案将推进研究基础设施 已成功利用 NPCRC 作为跨学科伙伴关系的协作工具 面向美国各地的实习生、初级和经验丰富的研究人员的老年姑息治疗研究