Research Education Core

研究教育部分摘要 哥伦比亚跨学科研究中心研究教育部分的目标 阿尔茨海默病差异（CIRAD）是提供指导和职业发展的机会， 试点研究和跨学科合作，以早期研究人员从代表性不足的背景 有兴趣在CIRAD的专题重点研究生涯，在阿尔茨海默病的差异研究 城市西班牙裔和非西班牙裔黑人中的痴呆和相关痴呆（ADRD），包括生物学， 行为，社会文化，环境风险和恢复力因素，生物标志物，和生物标志物。所述REC 将支持：（a）试点研究计划;（B）ADRD研究指导计划;（c）指导计划 在健康差异和少数民族老龄化研究方面。广泛需要培养熟练的劳动力 用于研究ADRD中的差异。由于美国人口老龄化，ADRD患者人数 正在增加。少数民族中ADRD患者人数的指数增长更大， 特别是西班牙裔和非西班牙裔黑人，与非西班牙裔白人相比。健康研究 与ADRD相关的差异需要跨学科的方法，包括对社会决定因素的研究 健康（SDOH），行为科学，心理健康，流行病学，ADRD生物标志物，神经心理学， 测量、生物统计学、生物信息学、临床试验和验证。为此，REC将利用 CIRAD教师的专业知识，阿尔茨海默病研究中心（ADRC）的专业知识和资源， 哥伦比亚大学医学中心（CDC）和纽约市地区的其他杰出合作者。的 REC将由CIRAD首席研究员（PI）Luchsinger和Manly领导，他们在以下方面有着良好的记录： 指导ADRD和健康差异的早期研究者。区域经济委员会将通过以下方式实现其目标： 具体目标：具体目标1：支持一个试点项目计划，该计划将在早期阶段征求申请 调查人员来自代表性不足的背景下，在纽约市和纽约市大都市区， 该中心的主题重点，并资助至少3个项目，每年至少35,000美元的奖励，12- 2、具体目标;为支持试点项目供资调查员的职业发展， 谁将被命名为RCMAR科学家，通过一个持续的指导计划;具体目标3。支持 继国家之后，指导RCMAR科学家在ADRD的健康差异和少数族裔老龄化研究方面的工作 老龄化研究所（NIA）的差距研究框架;具体目标4。要衡量目标1至 3.通过与行政核心协调的总结和形成过程。

RESEARCH EDUCATION COMPONENT SUMMARY The goal of the Research Education Component (REC) of the Columbia Center for Interdisciplinary Research on Alzheimer’s Disease Disparities (CIRAD) is to provide opportunities for mentoring and career development, pilot studies, and interdisciplinary collaboration to early investigators from under-represented backgrounds interested in a research career in the thematic focus of the CIRAD, research in disparities in Alzheimer’s disease and related dementias (ADRD) among Urban Hispanic and Non-Hispanic Blacks, including biological, behavioral, sociocultural, and environmental risk and resilience factors, biomarkers, and caregiving. The REC will support: (a) a pilot studies program; (b) a mentoring program in ADRD research; and (c) a mentoring program in health disparities and minority aging research. There is extensive need for development of a skilled workforce for the study of disparities in ADRD. Due to the aging of the US population, the numbers of persons with ADRD are increasing. The exponential rise of numbers of people with ADRD is greater among ethnic minorities, particularly Hispanics and non-Hispanic Blacks, compared with Non-Hispanic Whites. The study of health disparities related to ADRD requires a transdisciplinary approach that includes research in social determinants of health (SDOH), behavioral science, mental health, epidemiology, ADRD biomarkers, neuropsychology, measurement, biostatistics, bioinformatics, clinical trials, and caregiving. To this end, the REC will leverage the expertise of CIRAD faculty, the expertise and resources of the Alzheimer’s Disease Research Center (ADRC) at Columbia University Medical Center (CUMC), and other prominent collaborators in the New York City area. The REC will be led by CIRAD principal investigators (PI) Luchsinger and Manly, who have a strong track record of mentoring early investigators in ADRD and health disparities. The REC will achieve its goals through the following specific aims: Specific aim 1: To support a pilot project program that will solicit applications from early stage investigators from under-represented backgrounds at CUMC and the New York City metropolitan area in the thematic focus of the center, and to fund at least 3 projects annually with awards of at least $35,000 each, of 12- months duration; Specific aim 2. To support the career development of investigators funded for pilot projects, who will be named RCMAR Scientists, through a continuing mentoring program; Specific aim 3. To support mentoring of RCMAR Scientists in health disparities and minority aging research in ADRD, following the National Institute on Aging (NIA) disparities research framework; Specific aim 4. To measure success in aims 1 through 3 through summative and formative processes in coordination with the administrative core.