Core A - Administrative Core

核心 A - 行政核心

• 批准号: 10300067
• 负责人: JOSEPH G GLEESON
• 金额: $ 13.6万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10300067
• 关键词: Administrator; Animal Model; Animals; Applications Grants; Bioinformatics; Budgets; Businesses; Child; Clinical; Collaborations; Colorado; Core Grant; Data Analytics; Development; Diagnosis; Epigenetic Process; Faculty; Genetic; Genetic Screening; Genomics; Goals; Grant; Group Meetings; Hour; Human; Human Genome Project; Individual; Institution; Knowledge; Meningomyelocele; Modeling; Molecular Diagnosis; Mus; Nature; Neural Tube Defects; Prevention; Rana; Research; Research Personnel; Resources; Sampling; Scientist; Structural Congenital Anomalies; Structural defect; Techniques; Technology; Time; Training; Translations; Travel; Universities; Videoconferencing; Work; design; educational atmosphere; epigenomics; functional genomics; gene environment interaction; genetic approach; genome sequencing; improved; innovation; insight; meetings; member; multidisciplinary; programs; response; reverse genetics; single cell sequencing; symposium; technological innovation; whole genome

PROJECT SUMMARY – Core A: Administrative Core This Administrative Core (Core A) will have two major functions. First, it will provide administrative support and intellectual enrichment for the investigators in this Program. Due to the fact that the Program includes five senior investigators from three institutions (UCSD, Salk, U Colorado), each in a different department, Core A will be essential to integrate the disparate administrative hierarchies. Additionally three different vertebrate species will be used for this work (human, mouse, frog), with the need to move animals between institutions. Because of this, and because of the multi-disciplinary nature of the Program, a central Administrative Core is essential. The Core will work closely with the administration of the three partner institutions, as well as administrators, business managers, and scientists in each department involved. The Administrative Core will: 1] Provide and encourage intellectual collaboration between members of the Program Project, Internal and External Advisory Panels, university faculty who are not members of the Project, and outside consultants. 2] Assist individual PIs in budgeting as well as coordinating travel, purchasing, meetings, and seminars. The Core will achieve these objectives in several ways: 1] We will support a Slack instant messaging/video portal for routine programmatic issues. 2] We will have monthly two-hour seminars for all Program members in this program via video conference. 3] We will have semiannual review by the Internal Advisory Group, and biennial Retreats by the External Advisory Group, with presentation by each PI. We will also have the Directors of Core B and C present new data, analytical techniques, and technological innovations, especially in the rapidly moving fields of genomics, epigenomics, and bioinformatics. Seminars will average 10-12 per year, with each Project or Core presenting 2-3 times per year. Internal and External Advisors are selected to advise each project specifically and will work directly with his/her PI regarding their progress, to suggest possible new directions for both the individual Projects, and potentially the overall Program. In addition, we propose to have two whole day symposia during Year 2 and Year 4, overlapping with the External Advisory Group meetings, in which will invite scientists whose work is on the same aspect of the research of each project. During these symposia, each of the PI’s will present their progress over the preceding two years in the outside experts will be asked to critically evaluate progress of each Project.

项目摘要 - 核心A：行政核心 该管理核心（核心A）将具有两个主要功能。首先，它将提供行政支持 和该计划中的调查人员的智能丰富。由于该程序包括 来自三个机构（UCSD，SALK，UCORODO）的五名高级调查员，每个部门都在另一个部门 核心A对于整合不同的管理层次结构至关重要。另外三个不同 脊椎动物物种将用于这项工作（人，老鼠，青蛙），需要在之间移动动物 机构。因此，由于该计划的多学科性质，是一个中心 行政核心是必不可少的。核心将与三个合作伙伴的管理紧密合作 机构以及每个部门的管理人员，业务经理和科学家。 行政核心将：1]提供并鼓励成员之间的智力合作 计划项目，内部和外部咨询小组，大学教职员工 项目和外部顾问。 2]协助单个PI进行预算和协调旅行， 采购，会议和下水道。核心将通过几种方式实现这些目标：1]我们将 支持Slack Instant消息传递/视频门户，以解决常规的程序化问题。 2]我们将每月举行 该计划中的所有计划成员通过视频会议为两个小时的下水道。 3]我们将有 内部咨询小组的半年度审查，以及外部咨询小组双年展的务虚会， 每个pi的介绍。我们还将有Core B和C的董事呈现新数据，分析性 技术和技术创新，尤其是在基因组学快速移动的领域中， 表观基因组学和生物信息学。每个项目或核心的研讨会平均每年为10-12 每年呈现2-3次。选择内部和外部顾问来为每个项目提供建议 具体并将直接与他/她的PI有关他们的进度，建议可能的新方向 对于各个项目，也可能是整体计划。此外，我们建议有两个 在第2年和第4年期间的一整天研讨会，与外部咨询小组会议重叠， 这将邀请其工作在每个项目研究的相同方面的科学家。在这些期间 座谈会，每个PI都会在前两年的外部专家中展示他们的进度 将要求批判性地评估每个项目的进度。