Core A - Administrative Core

核心 A - 行政核心

• 批准号: 10300067
• 负责人: JOSEPH G GLEESON
• 金额: $ 13.6万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10300067
• 关键词: Administrator; Animal Model; Animals; Applications Grants; Bioinformatics; Budgets; Businesses; Child; Clinical; Collaborations; Colorado; Core Grant; Data Analytics; Development; Diagnosis; Epigenetic Process; Faculty; Genetic; Genetic Screening; Genomics; Goals; Grant; Group Meetings; Hour; Human; Human Genome Project; Individual; Institution; Knowledge; Meningomyelocele; Modeling; Molecular Diagnosis; Mus; Nature; Neural Tube Defects; Prevention; Rana; Research; Research Personnel; Resources; Sampling; Scientist; Structural Congenital Anomalies; Structural defect; Techniques; Technology; Time; Training; Translations; Travel; Universities; Videoconferencing; Work; design; educational atmosphere; epigenomics; functional genomics; gene environment interaction; genetic approach; genome sequencing; improved; innovation; insight; meetings; member; multidisciplinary; programs; response; reverse genetics; single cell sequencing; symposium; technological innovation; whole genome

PROJECT SUMMARY – Core A: Administrative Core This Administrative Core (Core A) will have two major functions. First, it will provide administrative support and intellectual enrichment for the investigators in this Program. Due to the fact that the Program includes five senior investigators from three institutions (UCSD, Salk, U Colorado), each in a different department, Core A will be essential to integrate the disparate administrative hierarchies. Additionally three different vertebrate species will be used for this work (human, mouse, frog), with the need to move animals between institutions. Because of this, and because of the multi-disciplinary nature of the Program, a central Administrative Core is essential. The Core will work closely with the administration of the three partner institutions, as well as administrators, business managers, and scientists in each department involved. The Administrative Core will: 1] Provide and encourage intellectual collaboration between members of the Program Project, Internal and External Advisory Panels, university faculty who are not members of the Project, and outside consultants. 2] Assist individual PIs in budgeting as well as coordinating travel, purchasing, meetings, and seminars. The Core will achieve these objectives in several ways: 1] We will support a Slack instant messaging/video portal for routine programmatic issues. 2] We will have monthly two-hour seminars for all Program members in this program via video conference. 3] We will have semiannual review by the Internal Advisory Group, and biennial Retreats by the External Advisory Group, with presentation by each PI. We will also have the Directors of Core B and C present new data, analytical techniques, and technological innovations, especially in the rapidly moving fields of genomics, epigenomics, and bioinformatics. Seminars will average 10-12 per year, with each Project or Core presenting 2-3 times per year. Internal and External Advisors are selected to advise each project specifically and will work directly with his/her PI regarding their progress, to suggest possible new directions for both the individual Projects, and potentially the overall Program. In addition, we propose to have two whole day symposia during Year 2 and Year 4, overlapping with the External Advisory Group meetings, in which will invite scientists whose work is on the same aspect of the research of each project. During these symposia, each of the PI’s will present their progress over the preceding two years in the outside experts will be asked to critically evaluate progress of each Project.

项目摘要 – 核心 A：行政核心 该行政核心（核心 A）将具有两个主要职能。首先，它将提供行政支持 以及本项目研究人员的知识丰富。由于该计划包括 来自三个机构（加州大学圣地亚哥分校、索尔克大学、科罗拉多大学）的五名高级研究人员，每个机构都在不同的部门， 核心 A 对于整合不同的管理层级至关重要。另外还有三种不同的 这项工作将使用脊椎动物物种（人类、小鼠、青蛙），需要在不同物种之间移动动物 机构。正因为如此，并且由于该计划的多学科性质，一个中央 行政核心至关重要。核心将与三个合作伙伴的管理部门密切合作 机构以及各相关部门的管理人员、业务经理和科学家。这 行政核心将： 1] 提供并鼓励成员之间的智力合作 计划项目、内部和外部顾问小组、非委员会成员的大学教员 项目和外部顾问。 2] 协助个人 PI 制定预算并协调差旅， 采购、会议和研讨会。核心将通过多种方式实现这些目标： 1] 我们将 支持 Slack 即时消息/视频门户解决常规编程问题。 2]我们每月都会有 通过视频会议为该计划的所有计划成员举办两小时的研讨会。 3]我们将有 内部咨询小组每半年进行一次审查，外部咨询小组每两年进行一次务虚会， 每个 PI 的演示。我们还将请核心 B 和 C 的董事提供新数据、分析 技术和技术创新，特别是在快速发展的基因组学领域， 表观基因组学和生物信息学。研讨会平均每年 10-12 场，每个项目或核心 每年呈现2-3次。选择内部和外部顾问为每个项目提供建议 具体而言，将直接与他/她的 PI 合作了解他们的进展，以提出可能的新方向 对于单个项目，以及可能的整个计划。此外，我们建议设立两个 第二年和第四年全天的研讨会与外部顾问小组会议重叠， 这将邀请与每个项目研究相同方面的科学家。在这些期间 研讨会上，每位 PI 都会向外部专家介绍他们过去两年的进展 将被要求严格评估每个项目的进展。