An Informatics Platform for Objectively Quantifying Electric Power Wheelchair Usage for those with Alzheimer's Disease, Alzheimer's Disease Related Dementias, and Cognitive Impairments

项目概要/摘要 建议是一个信息化平台的照顾者轮椅操作员或风险的发展 阿尔茨海默病（AD）、阿尔茨海默病相关痴呆（AD/ADRD）和认知障碍。 重要性：许多老年人有慢性健康状况，限制了行动能力，因此，轮椅的使用是 这是保持独立性的必要条件。然而，当老年轮椅使用者表现出认知障碍的迹象时， 与发展中的痴呆症相关的衰退，照顾者必须做出艰难的，主观的选择， 独立的流动性。目前还没有一个系统可以监测和量化微妙减少驾驶 能力.假设：我们假设直接观察轮椅使用者的驾驶行为可以 定量区分正常和受损的操作。这样的系统可以告知护理人员 在事件发生之前，干预可能是必要的，应该审查轮椅的使用情况， 停职了相反，它可以让许多患者继续使用轮椅，提供照顾者， 对患者能力的一致的、社区内的测量，反映他们当前的认知状态。具体目标： 在第二阶段，IDL和它的合作者将：（1）开发一个生产就绪的系统，（2）执行一个监控， 对电动轮椅使用者的研究（非临床试验），以及（3）评估系统和算法性能 量化驾驶习惯和认知变化。

Project Summary/Abstract Proposed is an informatics platform for caregivers of wheelchair operators with or at risk of developing Alzheimer’s disease (AD), Alzheimer's Disease Related Dementias (AD/ADRD), and cognitive impairments. Significance: Many older adults have chronic health conditions that limit mobility and, thus, wheelchair use is essential for maintaining independence. However, when an older wheelchair user exhibits signs of cognitive decline related to developing dementia, caregivers must make hard, subjective choices trading safety with independent mobility. Currently there is no system that can monitor and quantify subtly diminishing driving abilities. Hypothesis: We hypothesize that direct observation of a wheelchair user’s driving behavior can quantitatively distinguish between normal and impaired operation. Such a system could inform caregivers before an incident that intervention may be necessary and wheelchair use should be reviewed and possibly suspended. Conversely, it may allow many patients to continue wheelchair use by providing caregivers a consistent, in-community measure of a patient’s abilities reflecting their current cognitive state. Specific Aims: In Phase II, IDL and its collaborators will: (1) Develop a production-ready system, (2) Perform a monitoring study with powered wheelchair users (non-clinical trial), and (3) Evaluate system and algorithm performance quantifying driving habits and cognitive changes.