University of Pittsburgh Clinical and Translational Science Institute

匹兹堡大学临床与转化科学研究所

基本信息

批准号：
10642831
负责人：
STEVEN E REIS
金额：
$ 1014.75万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-12 至 2026-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10642831
关键词：
Acceleration Address Age Articulation Belief Caring Clinical Clinical Research Clinical Sciences Clinical Trials Network Collaborations Communities Community Networks Competence Devices Discipline Dissemination and Implementation Ecosystem Elderly Environment Foundations Healthcare Systems Heterogeneity Individual Informatics Infrastructure Institution Lead Methods Mission Multi-Institutional Clinical Trial Newborn Infant Participant Patients Pennsylvania Policy Maker Population Pragmatic clinical trial Preventive Process Provider Public Health Registries Research Research Design Research Methodology Research Personnel Research Training Resources Scientist Services Societies Therapeutic Training Translational Research Translations Trust Universities Vision Voice Work Workforce Development advanced analytics catalyst cohort community engagement community organizations comparative effectiveness cultural values design effectiveness clinical trial experience health practice informatics tool member novel diagnostics operation peer precision medicine clinical trials programs research study tool workforce needs

项目摘要

Since 2006, the Clinical and Translational Science Institute (CTSI) has fundamentally transformed the University of Pittsburgh (Pitt) and its approach to training scientists (2,419), its conduct of research (6,551 studies), and its community engagement (>200 community partners) and the integration of research in health practice across western Pennsylvania (>250K research participants in Pitt+Me Registry). We established clinical and translational science as a new academic discipline across Pitt and its affiliated healthcare system, UPMC, and created the infrastructure and workforce needed to sustain it. We are now poised to pivot from successfully enabling the sequential translation of individual studies to systematically accelerating the real- world impact of research. We define “research impact” as changing standards of care through the dissemination and sustained implementation of best practices supported by translational research evidence. Over the next 5 years, we will provide the training, resources, and expertise necessary for CTSI-supported studies to develop a “path to impact” and thus support progress toward achieving our mission: CTSI will accelerate the dissemination and implementation, and hence the impact, of translational research. Each CTSI program has new activities specifically designed to support specific steps on the path from idea to impact: Team Assembly, Study Design, Study Conduct, Dissemination & Implementation. We will create translational research teams who envision the impact of their work on the communities that they seek to benefit (patients, providers, policymakers, etc.) at each step of the research process, from conceptualizing questions through implementing findings. Every CTSI-supported study will be “designed for impact”.

自2006年以来，临床和转化科学研究所（CTSI）从根本上改变了匹兹堡大学（皮特）及其培训科学家的方法（2,419），其研究的行为（6,551 研究）及其社区参与（> 200个社区伙伴）及其健康研究的整合整个宾夕法尼亚州西部的练习（> 250k Pitt+ME注册表的研究参与者）。我们建立了临床和翻译科学是皮特及其会员医疗系统的新学科， UPMC，并创建了维持它所需的基础设施和劳动力。我们现在被中毒从成功地实现了单个研究的顺序翻译，以系统地加速实现世界研究的影响。我们将“研究影响”定义为通过不断变化的护理标准转化研究证据支持的最佳实践的传播和持续实施。在接下来的5年中，我们将提供CTSI支持的培训，资源和专业知识研究发展“影响途径”，从而支持实现我们的使命的进步：CTSI将加速转化研究的传播和实施，从而加速转化研究的影响。每个CTSI 计划具有专门设计的新活动，以支持从想法到影响的路径上的特定步骤：团队组装，研究设计，研究行为，传播和实施。我们将创建翻译设想工作对他们寻求受益社区的影响的研究团队（患者，在研究过程的每个步骤中，提供者，政策制定者等实施发现。每项CTSI支持的研究都将“为撞击设计”。