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University of Pittsburgh Clinical and Translational Science Institute

匹兹堡大学临床与转化科学研究所

基本信息

批准号：
9339795
负责人：
STEVEN E REIS
金额：
$ 320.31万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-12 至 2021-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9339795
关键词：
Achievement Adopted Businesses Clinic Clinical Clinical Data Clinical Sciences Clinical Trials Network Collaborations Communities Complex Databases Discipline Education Engineering Ensure Entrepreneurship Environment Family Goals Government Health Professional Home environment Individual Industry Informatics Institutes Institution Knowledge Leadership Life Cycle Stages Literature Longevity Manuscripts Medical center Methodology Methods Modeling Multi-Institutional Clinical Trial Patients Pennsylvania Population Process Publishing Research Research Infrastructure Research Methodology Research Personnel Research Support Research Training Science Scientist Secure Students TNFSF15 gene Time Training Training Programs Translating Translational Research Translations Universities Work Workforce Development advocacy organizations catalyst data sharing design forging innovation learning progression member named group novel strategies personalized approach programs research study skills tenure track tool

项目摘要

In 2006, we created the University of Pittsburgh Clinical and Translational Science Institute (CTSI) as the academic home for clinical and translational science in western Pennsylvania. We revolutionized the practice of translational research at Pitt and at our partnering institution, the University of Pittsburgh Medical Center (UPMC), by training 850 translational scientists, incorporating team science in the promotions and tenure process, supporting 2225 investigators and 4049 research studies, and forging a collaborative research environment. We created and led the SPIRiT Consortium (6 CTSA hubs) and the NCATS Accrual to Clinical Trials network (21 CTSA hubs). Published manuscripts from a broad range of translational research studies that directly benefitted from CTSI support have been cited >81,000 times in the literature. Over the next 5 years, we will apply our infrastructure, training programs, best practices, and novel approaches to support translational science and scientists and to advance each of the national CTSA goals through our Overall Aims: 1) Workforce Development: Enhance and expand our diverse and team-oriented translational science workforce by providing them with the specialized skills, knowledge, and core competencies required to advance translation of their discoveries through innovative education methods, experiential training, and continuous learning opportunities; 2) Collaboration and Engagement: Engage an inclusive group of stakeholders as partners in the full translational research process and enable their contributions as members of teams conducting collaborative research; 3) Integration: Integrate into research programs those populations that have been traditionally excluded or studied in isolation and support and enhance studies that span the lifespan and translational research spectrum; 4) Methods/Processes: Promote innovation, quality, and efficiency across the translational research spectrum by developing and disseminating new research methodologies; adopting best practices from CTSA hubs, industry, and sectors outside of translational science; facilitating project management; and streamlining institutional research processes, with an emphasis on multi-center clinical trials; and 5) Informatics: Infuse informatics tools and methodologies across the research life cycle and translational research spectrum, efficiently integrate research and clinical data in a secure research data repository, and enable secure data sharing locally and nationally. In addition to the 7 required Components and our rigorous KL2 and TL1 training programs, we will expand our range and breadth of accomplishments through two Optional Components that leverage great strengths and opportunities in Innovation as a Discipline and Biomedical Modeling. Thus, the impact of CTSI, with its exceptional institutional support and committed and enthusiastic team, will continue to be significant, locally, regionally, and nationally.

2006年，我们创建了匹兹堡大学临床与转化科学研究所（CTSI）