Investigating SARS-CoV-2 Vaccine Hesitancy in Houston

摘要 拟议中的RCMI健康成瘾研究和癌症预防中心旨在建立一个 社区参与研究如何加速科学突破的国家典范， 由受过培训的外行人直接在目标社区迅速传播和实施， 辅助专业人员。这将通过成功完成五个具体目标来实现：目标1。执行 集中的研究基础设施核心，将提高科学的严谨性，生产力和影响力， 健康公平科学通过五个主要服务：（1）研究方法;（2）实验室技术和 设施;（3）数据管理和生物统计学;（4）健康信息学;以及（5）负责任的行为 研究，伦理学，在健康差距研究的合规性;目标2。执行小组辅导计划， 行政核心，为任职人数不足的人提供数据驱动的职业发展活动 少数民族（URM）博士后研究员和助理教授追求健康公平科学的职业生涯;目标3。 战略性地增加研究人员的应用和成功-在健康科学领域代表性不足 - 通过试点资助计划和创新研究，确保具有竞争力的NIH研究赠款 由研究者发展核心管理的会谈;目标4。利用社区参与核心 促进与社区成员的公平、协作和可持续的伙伴关系， 组织和利益相关者，以实现双向“信息交换”， 研究结果对实现卫生公平的影响;目标5。促进对少数群体健康的研究， 通过公开的同行评审出版物传播区域协调机制的成果， 演讲，白色文件，政策简报，以及其他材料，活动，或服务传播到 社区这种变革性的基础设施-与UH管理员，社区 成员、利益相关者、组织和民选官员-提供了一种可持续的数据驱动方法， 拯救生命，防止成瘾和癌症对边缘化群体和 在休斯顿大都市及其他地区服务不足的社区。

ABSTRACT The proposed RCMI HEALTH Center for Addictions Research and Cancer Prevention is designed to establish a national exemplar for how community-engaged research can accelerate scientific breakthroughs that can be rapidly disseminated and implemented directly into the targeted community by trained laypersons or paraprofessionals. This will be achieved by the successful completion of five specific aims: Aim 1. Execute a centralized Research Infrastructure Core that will enhance scientific rigor, productivity, and impact of health-equity science through five primary services: (1) Research Methodology; (2) Laboratory Techniques and Facilities; (3) Data Management and Biostatistics; (4) Health Informatics; and (5) Responsible Conduct of Research, Ethics, and Compliance in health-disparities research; Aim 2. Execute a group mentoring program in the Administrative Core that provides data-driven career enhancement activities for underrepresented minority (URM) postdoctoral fellows and assistant professors pursuing careers in health-equity science; Aim 3. Strategically increase the application and success of investigators – underrepresented in the health sciences – securing competitive NIH research grants through the Pilot Grant Program and Innovation Research Talks administered by the Investigator Development Core; Aim 4. Leverage the Community Engagement Core to facilitate equitable, collaborative, and sustainable partnerships with community members, organizations, and stakeholders to enable a bidirectional “exchange of information” that advances the potential impact of research findings for achieving health equity; and Aim 5. Promote research on minority health and health disparities by disseminating RCMI outcomes through publicly available peer-reviewed publications, presentations, white papers, policy briefs, and other materials, activities, or services disseminated into the community. This transformative infrastructure – in partnership with UH administrators, community members, stakeholders, organizations, and elected officials – provides a sustainable data-driven approach for saving lives and preventing addictions and cancer from disproportionally afflicting marginalized and underserved communities in metropolitan Houston and beyond.