Investigating SARS-CoV-2 Vaccine Hesitancy in Houston

摘要 拟议的RCMI成瘾研究和癌症预防健康中心旨在建立一个 社区参与研究如何加快科学突破的国家典范 由训练有素的非专业人员直接向目标社区传播和实施 职业辅导员。这将通过成功完成五个具体目标来实现：目标1.执行 集中式研究基础设施核心，将增强科学严谨性、工作效率和影响 通过五项主要服务：(1)研究方法；(2)实验室技术和 设施；(3)数据管理和生物统计；(4)健康信息学；和(5)负责任的行为 健康差异研究中的研究、伦理和遵从性；目标2.在 为任职人数不足的人员提供数据驱动的职业提升活动的管理核心 少数群体(URM)博士后研究员和助理教授追求健康-公平科学的职业；目标3。 战略性地增加研究人员的应用和成功--在健康科学中代表性不足 -通过试点拨款计划和创新研究获得有竞争力的NIH研究拨款 由调查员发展核心管理的讲座；目标4.利用社区参与核心 为促进与社区成员建立公平、协作和可持续的伙伴关系， 组织和利益相关者实现双向的信息交换，以促进潜在的 研究结果对实现健康公平的影响；和目标5.促进关于少数群体健康和 健康差距，通过公开的同行评议出版物传播RCMI成果， 演示文稿、白皮书、政策简报以及传播到 社区。这一变革性基础设施-与UH管理员、社区合作 成员、利益相关者、组织和民选官员-提供可持续的数据驱动方法 挽救生命，防止成瘾和癌症不成比例地折磨边缘化和 休斯敦大都市及更远地区服务不足的社区。

ABSTRACT The proposed RCMI HEALTH Center for Addictions Research and Cancer Prevention is designed to establish a national exemplar for how community-engaged research can accelerate scientific breakthroughs that can be rapidly disseminated and implemented directly into the targeted community by trained laypersons or paraprofessionals. This will be achieved by the successful completion of five specific aims: Aim 1. Execute a centralized Research Infrastructure Core that will enhance scientific rigor, productivity, and impact of health-equity science through five primary services: (1) Research Methodology; (2) Laboratory Techniques and Facilities; (3) Data Management and Biostatistics; (4) Health Informatics; and (5) Responsible Conduct of Research, Ethics, and Compliance in health-disparities research; Aim 2. Execute a group mentoring program in the Administrative Core that provides data-driven career enhancement activities for underrepresented minority (URM) postdoctoral fellows and assistant professors pursuing careers in health-equity science; Aim 3. Strategically increase the application and success of investigators – underrepresented in the health sciences – securing competitive NIH research grants through the Pilot Grant Program and Innovation Research Talks administered by the Investigator Development Core; Aim 4. Leverage the Community Engagement Core to facilitate equitable, collaborative, and sustainable partnerships with community members, organizations, and stakeholders to enable a bidirectional “exchange of information” that advances the potential impact of research findings for achieving health equity; and Aim 5. Promote research on minority health and health disparities by disseminating RCMI outcomes through publicly available peer-reviewed publications, presentations, white papers, policy briefs, and other materials, activities, or services disseminated into the community. This transformative infrastructure – in partnership with UH administrators, community members, stakeholders, organizations, and elected officials – provides a sustainable data-driven approach for saving lives and preventing addictions and cancer from disproportionally afflicting marginalized and underserved communities in metropolitan Houston and beyond.