South Carolina Cancer Disparities Research Center (SC CaDRe)

SC干部1U54CA210963-01A1 过桥资金 摘要这项为期五年的U54提案是一个协作的、机构间的伙伴关系 在南卡罗来纳州立大学(SCSU)、历史上的黑人大学(HBCU)和 南卡罗来纳医科大学霍林斯癌症中心(MUSC-HCC)，国家 癌症研究所-指定的癌症中心。这一合作伙伴关系始于2011年，由 NCI P20 CPACHE赠款，并已发展到产生U54南卡罗来纳州癌症差异 研究中心(SC干部)申请。在他们的联合社区合作伙伴的帮助下， 奥兰治堡马布里癌症中心区域医学中心(RMC-MCC)，两家机构的研究人员 各机构合作设计了SC干部。高级公务员干部的首要目标是 提高华南理工大学进行跨学科癌症研究的能力，并进一步加强 并延伸纵向研究教育管道，将催化新一代多样化的 生物医学研究人员将重点放在癌症差异上。SC干部有三大主题。 第一个重点是评估肥胖与前列腺癌和乳腺癌的关系。 差距。第二个主题强调对晚期糖基化终末产物(AGEs)的评估 作为一种与癌症、癌症差异和肥胖相关的新生物标志物。第三个主题亮点 包括美国东南沿海地区独有的人口--海岛 (西语)/古拉族人口。在五年内，SC干部的目标是：1)进一步阐明 导致癌症差异的分子机制；2)增强的不同 癌症研究人员；3)由南加州大学教职员工领导的NIH研究提案增加，如 独立的调查人员；以及4)社区更多地参与癌症研究。由于 SCSU/MUSC-HCC长期的学术伙伴关系和每个实体的研究和 教育优势和社区关系，SC干部准备改变癌症 南卡罗来纳州人的健康后果

SC CADRE 1U54CA210963-01A1 Bridge Funding SUMMARY This five-year U54 proposal is a collaborative, inter-institutional partnership between South Carolina State University (SCSU), an Historically Black University (HBCU), and the Medical University of South Carolina Hollings Cancer Center (MUSC-HCC), a National Cancer Institute-designated cancer center. The partnership began in 2011 under the auspices of an NCI P20 CPACHE grant and has grown to produce this U54 South Carolina Cancer Disparities Research Center (SC CADRE) application. With input from their joint community partner, the Regional Medical Center of Orangeburg Mabry Cancer Center (RMC-MCC), investigators at both institutions collaborated to design the SC CADRE. The overarching goals of the SC CADRE are to increase SCSU’s capacity to conduct transdisciplinary cancer research and to further strengthen and extend a longitudinal research education pipeline that will catalyze a new diverse generation of biomedical researchers focused on cancer disparities. The SC CADRE has three major themes. The first focuses on evaluating the relationship between obesity and prostate and breast cancer disparities. The second theme emphasizes evaluation of advanced glycation endproducts (AGEs) as a novel biomarker related to cancer, cancer disparities, and obesity. The third theme highlights the inclusion of a population unique to the US southeastern coastal region, the Sea Island (SI)/Gullah population. Within five years, the SC CADRE aims for: 1) further elucidation of molecular mechanisms contributing to cancer disparities; 2) an enhanced pipeline of diverse cancer researchers; 3) an increased number of NIH research proposals led by SCSU faculty as independent investigators; and 4) greater community engagement in cancer research. Due to the longstanding SCSU /MUSC-HCC academic partnership and each entity’s research and educational strengths and community relationships, the SC CADRE is poised to transform cancer health outcomes for South Carolinians