Integrated Health Sciences Core

摘要(综合健康科学核心) 密歇根生命、环境暴露和疾病中心(M-LEEAD)的任务是 加快研究确定脆弱生命期间环境暴露的影响 分阶段并促进研究成果的转化，以改进临床和公共卫生干预措施 用于减轻人类疾病的影响。为了支持这项任务，M-Leead的综合健康科学 (IHS)Core促进环境健康科学家、临床研究人员之间的多方向互动 和从业者、定量研究科学家和环境健康实践专业人员，导致 加强将研究成果转化为公共卫生实践。在这场竞争性的更新中，我们在 在加强研究与社区和实践需求之间的联系方面取得了成功， 与社区参与核心(CEC)建立伙伴关系。IHS的核心目标是：确定和 便利获取人类和动物生物库，促进多方向翻译研究，以 确保研究设计的质量，提供统计支持，并将调查人员与服务联系起来 由M-Leead内核和其他UM资源提供。IHS核心提供尖端的统计数据 促进环境健康研究并促进将其转化为实践和政策的方法。 IHS核心提供了关键的联系功能，促进了翻译学术和多学科的合作 通过与CEC的密切协调，建立定向的利益攸关方伙伴关系。具体地说，IHS核心 旨在1)为中心研究人员提供高质量的研究设计、实验室和资料库 促进环境健康研究的方案和统计支持；2)教育和培训 研究设计、社区参与研究的中心调查人员、工作人员、学生和从业者， 实验室实践、生物信息库的管理以及通过研讨会和 研讨会；3)促进跨学科合作，促进翻译研究；4)维护 并更新可搜索的、基于网络的Kiosk，以提供有关人类和动物研究的信息以及 M-Leead中心的核心服务；以及5)协调促进多方向伙伴关系 与CEC、从业者和社区成员联系环境风险研究 在人们生活、工作和娱乐的整个过程中，这些因素都会影响到这些地点。IHS的核心 为中心成员提供基础/常规统计支持和前沿统计 促进环境健康的方法。IHS核心促进了M-LEEAD的翻译 通过主办环境统计和环境健康实践研讨会实现研究愿景 系列片。讲习班的传播是通过M-Leead网站进行的，IHS核心已经实现了 在解决密歇根州环境健康问题方面的具体影响(例如，全氟化碳/多溴联苯) 科学家、从业者和社区成员参加的演讲、网络研讨会和研讨会。

ABSTRACT (Integrated Health Sciences Core) The mission of the Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) is to accelerate research that defines the impact of environmental exposures during vulnerable life stages and promote translation of research findings to improve clinical and public health interventions for the mitigation of human disease. In support of this mission, M-LEEaD’s Integrated Health Sciences (IHS) Core facilitates multi-directional interaction among environmental health scientists, clinical researchers and practitioners, quantitative research scientists, and environmental health practice professionals, leading to enhanced translation of research findings into public health practice. In this competing renewal, we build on successes in strengthening connections between research and community and practice needs, in partnership with the Community Engagement Core (CEC). The IHS Core goals are: to identify and facilitate access to human and animal biobanks, to promote multi-directional translational research, to ensure quality of research designs, to provide statistical support, and to link investigators with services provided by M-LEEaD cores and other UM resources. The IHS Core offers cutting-edge statistical methods to advance environmental health research and facilitates translation to practice and policy. The IHS Core provides a critical linkage function promoting translational scholarship and multi- directional stakeholder partnerships, through close coordination with CEC. Specifically, the IHS Core aims to 1) provide Center investigators with high-quality study design, laboratory, and repository protocols, and statistical support for advancing environmental health research; 2) educate and train Center investigators, staff, students and practitioners in study design, community-engaged research, laboratory practice, curation of bio-repositories, and statistical methods through seminars and workshops; 3) promote interdisciplinary collaborations that foster translational research; 4) maintain and update the searchable, web-based Kiosk to provide information on human and animal studies and core services of the M-LEEaD Center; and 5) catalyze multi-directional partnerships, in coordination with CEC, with practitioners and community members to connect research on environmental risk factors to locations where people live, work, and play through-out the life-course. The IHS Core provides center members with both basic/routine statistical support and cutting-edge statistical methods to advance environmental health. The IHS Core facilitates the M-LEEaD translational research vision by hosting an environmental statistics and an environmental health practice workshop series. Dissemination of workshops occurs via the M-LEEaD website, and the IHS Core has achieved specific impact in addressing environmental health concerns in Michigan (e.g., PFAS/PBB) by offering presentations, webinars and symposia attended by scientists, practitioners, and community members.