Perovskite Based Foldable and Sensitive X-ray Imaging Detectors for Trauma Care
Perovskite Based Foldable and Sensitive X-ray Imaging Detectors for Trauma Care
批准号:
10650838
负责人:
Jinsong Huang
金额:
$33.89万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-07-01 至 2026-03-31
关键词:
AddressAdhesivesAreaCancer EtiologyCancer PatientCeramicsCeriumCharacteristicsChargeDNA DamageData CollectionDetectionDevelopmentDevicesDiagnosisDiagnostic EquipmentDoseElectrodesElectronicsElectronsEnvironmentExposure toFilmGenerationsGluesHospitalsImageImaging DeviceImaging TechniquesIndividualInjuryIonizing radiationLeadMammographyMechanicsMedical ImagingMembraneMetalsNatureNoiseNylonsPaste substancePatient imagingPatientsPatternPlayPolymersPositioning AttributeProcessRadiation-Induced CancerResearchResolutionRoentgen RaysRoleSemiconductorsSignal TransductionSilverSolventsSpeedStrontiumStructureTechniquesTechnologyX-Ray Computed TomographyX-Ray Medical ImagingYogaautomobile accidentcancer riskclinical diagnosticscostdesigndetectorfabricationflexibilityimagerimaging detectorimaging facilitiesimaging modalityimprovedlight emissionlight weightparticleperovskitepoint of careportabilitypractical applicationradiation riskresponsescreeningsimulationtomosynthesistrauma care
中文摘要
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英文摘要
Perovskite Based Foldable and Sensitive X-ray Imaging Detectors for Trauma Care
Project Summary/Abstract
X-ray imaging techniques including plain x-ray, tomosynthesis and computed tomography are the most
common and indispensable imaging modalities for screening and diagnosis. Trauma care needs the rapid
deployment of medical diagnostic devices and data collection to examine the injury of patient in complicated
environments, such as outside the hospitals or imaging-centers. Portable medical imaging devices such as X-
ray imaging devices are notably critical to address these needs. Since almost all present X-ray detectors are
made of the combination of scintillators with photodetector arrays, the portability of X-ray detectors is limited by
the rigid ceramic scintillators. Exposure to ionizing radiation is known to increase the risk of cancer due to the
damaging of DNA by X-ray. The current detectors are not sensitive enough so that a large dose is need to
achieve enough signal to noise ratio in imaging. The overall objective of this project is to yield a new generation
of X-ray detectors that are foldable, sensitive by overcoming the limitation of state-of-the-art detectors using
metal halide perovskites to directly convert X-ray into electrical signal. Direct conversion detectors have better
resolution than indirection ones, because it doesnot have the issue of nondirectional light emission in scintillators.
Perovskites are promising X-ray detection material by combining the strong stopping to X-ray and excellent
charge extraction capability. These detectors will be made to be like Yoga mats so that they can be folded for
easy carrying and quickly rolling-out or wrapping the point of care for inspection. A perovskite filled membrane
(PFM) structure will be used for multiple layer structure construction which have been demonstrated to have the
high sensitivity and easy to upscaled to large area for practical applications. Our specific objectives are: (Aim1)
establishing perovskite compositions, stacking structure and material fabrication process to develop sensitive
PFMs with large mobility-lifetime product, low noise, and excellent uniformity over a practical X-ray imaging
device area; (Aim2) developing a material design and process to integrate the X-ray detection perovskite films
into readout electronics with a robust mechanical connection and uniform electronic connection using several
soft materials based bonding techniques, The proposed technology has the potential to offer: (1) a factor of 10-
100 X patient imaging dose reduction; (2) increased imaging resolution; and (3) a flexibility and light weight
detector. The project leverages a recently discovered application of lead halide perovskites for ionization
radiation detection with demonstrated significantly higher sensitivity compared to the current mammography
detectors; Reducing the imaging dose will decrease the risk of radiation-induced cancer for patients, making the
screening process safer. Increasing the resolution will potentially lead to improved detection and analysis of
features in injury or sickness. The light-weight foldable detectors enable new applications in field for trauma care.
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Perovskite Based Foldable and Sensitive X-ray Imaging Detectors for Trauma Care
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批准号:10502805
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项目类别:
-
资助金额:$33.89万
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财政年份:2022
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负责人:Jinsong Huang
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依托单位:
海外基金