Postdoctoral Research Training in Anesthesiology and Critical Care Medicine

麻醉学和重症监护医学博士后研究培训

基本信息

  • 批准号:
    10651671
  • 负责人:
  • 金额:
    $ 61.49万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2006
  • 资助国家:
    美国
  • 起止时间:
    2006-07-01 至 2026-06-30
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY Although past advances in the field of Anesthesiology have made perioperative medicine remarkably safe for patients by comparison to historical standards, a myriad of important research questions that hold the keys to further progress in the allied fields of Anesthesia, Critical Care, and Pain Medicine remain unanswered. These questions exist in, but are not limited to, the following domains: (1) The mechanisms of action of anesthetic and sedative medications; (2) The systems biology of the perioperative state; (3) The mechanism and prevention of postoperative delirium and cognitive dysfunction; (4) Potential toxicity of anesthetic agents in the developing brain; (5) Maximization of safety related to human factors and communication throughout the perioperative period; (6) Development and testing of care pathways to improve long-term outcomes after surgery; (7) Sepsis and other causes of organ failure in intensive care; (8) Mechanisms and treatment of acute and chronic pain; and (9) Appropriate use of opioids and addiction prevention in the perioperative setting. To address these and other key questions that have the potential to improve public health, it is critically important to develop a core of well-trained and highly motivated physician-scientists within the Anesthesiology specialty who are dedicated to research and academics. The Department of Anesthesiology and Critical Care Medicine (ACCM) at the Johns Hopkins University (JHU) is submitting this renewal application for continued support of Postdoctoral Research Training in Anesthesiology (PRTA). In addition to providing an avenue for the support of Trainees, this program will continue to refine the approach whereby ACCM recruits talented and diverse young scientists engaged in Anesthesiology research and trains them via rigorous career development plans under the guidance of expert Faculty Mentors. Our principal aim is to develop the next generation of physician- scientists by endowing them with the tools and techniques best suited to their research while fostering innovation and the highest standards of scientific rigor. This aim is accomplished through a strong departmental research infrastructure that operates in conjunction with the incredible breadth and depth of the broader JHU scientific enterprise. Appointments are for two years, and key activities are mentored research and the potential for further education in the form of a relevant master's degree. As demonstrated in this application, ACCM has a long and productive history of clinical, translational, and basic research training in Anesthesiology, which the PRTA will continue to build upon and improve. Our previous success is highlighted by the career progression and scientific accomplishments of past Trainees, and our ongoing capacity to fulfill the mission of this Program is apparent in our outstanding pool of current and potential Trainees. We request continued funding for six Trainees per year for the so that we can continue to develop physician-scientists who will contribute to a secure scientific future in the field of Anesthesiology.
项目总结

项目成果

期刊论文数量(76)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons.
  • DOI:
    10.1097/ana.0000000000000360
  • 发表时间:
    2016-10
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Ryu YK;Mathena RP;Lim S;Kwak M;Xu M;Mintz CD
  • 通讯作者:
    Mintz CD
Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils.
  • DOI:
    10.1371/journal.pone.0071447
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Faraday N;Schunke K;Saleem S;Fu J;Wang B;Zhang J;Morrell C;Dore S
  • 通讯作者:
    Dore S
Cerebral Blood Flow Autoregulation in Sepsis for the Intensivist: Why Its Monitoring May Be the Future of Individualized Care.
  • DOI:
    10.1177/0885066616673973
  • 发表时间:
    2018-03
  • 期刊:
  • 影响因子:
    3.1
  • 作者:
    Goodson CM;Rosenblatt K;Rivera-Lara L;Nyquist P;Hogue CW
  • 通讯作者:
    Hogue CW
Why Aren't There More Female Pain Medicine Physicians?
  • DOI:
    10.1097/aap.0000000000000774
  • 发表时间:
    2018-07-01
  • 期刊:
  • 影响因子:
    5.1
  • 作者:
    Doshi, Tina L.;Bicket, Mark C.
  • 通讯作者:
    Bicket, Mark C.
Impact of Intensive Care Unit Nutrition on the Microbiome and Patient Outcomes.
重症监护病房营养对微生物组和患者预后的影响。
  • DOI:
    10.1016/j.anclin.2022.10.007
  • 发表时间:
    2023-03
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Serbanescu, Mara A;Da Silva, Monica;Zaky, Ahmet
  • 通讯作者:
    Zaky, Ahmet
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Cyrus David Mintz其他文献

Cyrus David Mintz的其他文献

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{{ truncateString('Cyrus David Mintz', 18)}}的其他基金

Toxic Effects of Anesthetics in Developing White Matter
麻醉药对白质发育的毒性作用
  • 批准号:
    10592303
  • 财政年份:
    2020
  • 资助金额:
    $ 61.49万
  • 项目类别:
Toxic Effects of Anesthetics in Developing White Matter
麻醉药对白质发育的毒性作用
  • 批准号:
    10372991
  • 财政年份:
    2020
  • 资助金额:
    $ 61.49万
  • 项目类别:
Mechanisms of Developmental Anesthesia Toxicity
发育麻醉毒性机制
  • 批准号:
    9159240
  • 财政年份:
    2016
  • 资助金额:
    $ 61.49万
  • 项目类别:
Mechanisms of Developmental Anesthesia Toxicity
发育麻醉毒性机制
  • 批准号:
    9335979
  • 财政年份:
    2016
  • 资助金额:
    $ 61.49万
  • 项目类别:
The effects of anesthetics on brain development
麻醉药对大脑发育的影响
  • 批准号:
    8424885
  • 财政年份:
    2013
  • 资助金额:
    $ 61.49万
  • 项目类别:
The effects of anesthetics on brain development
麻醉药对大脑发育的影响
  • 批准号:
    8788865
  • 财政年份:
    2013
  • 资助金额:
    $ 61.49万
  • 项目类别:
Postdoctoral Research Training in Anesthesiology and Critical Care Medicine
麻醉学和重症监护医学博士后研究培训
  • 批准号:
    10411889
  • 财政年份:
    2006
  • 资助金额:
    $ 61.49万
  • 项目类别:
The Role of ERM Proteins in Axonal Development
ERM 蛋白在轴突发育中的作用
  • 批准号:
    6927891
  • 财政年份:
    2003
  • 资助金额:
    $ 61.49万
  • 项目类别:

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麻醉学和重症监护医学博士后研究培训
  • 批准号:
    8487417
  • 财政年份:
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麻醉学和重症监护医学博士后研究培训
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麻醉学和重症监护医学博士后研究培训
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  • 财政年份:
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麻醉学和重症监护医学博士后研究培训
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    7250854
  • 财政年份:
    2006
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Postdoctoral Research Training in Anesthesiology and Critical Care Medicine
麻醉学和重症监护医学博士后研究培训
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  • 财政年份:
    2006
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    $ 61.49万
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麻醉学和重症监护医学博士后研究培训
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    7486259
  • 财政年份:
    2006
  • 资助金额:
    $ 61.49万
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Postdoctoral Research Training in Anesthesiology and Critical Care Medicine
麻醉学和重症监护医学博士后研究培训
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    2006
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麻醉学和重症监护医学博士后研究培训
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    2006
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    $ 61.49万
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麻醉学和重症监护医学博士后研究培训
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    8017816
  • 财政年份:
    2006
  • 资助金额:
    $ 61.49万
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