Global Cardiometabolic Disease Training

全球心脏代谢疾病培训

• 批准号: 10663800
• 负责人: Linda S Adair
• 金额: $ 23.92万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10663800
• 关键词: Cardiometabolic Disease; Training

Abstract We propose to renew our global cardiometabolic disease (GCMD) predoctoral training program. This cross- disciplinary nutrition-focused program provides specialized training to develop a cadre of researchers who can bridge basic, translational, and population science to reduce the growing burden and disparities in GCMD. There is critical need to reduce this burden in low- and middle-income countries that are disproportionately affected and where more specialized skills and global leadership are most needed. The training program is administered in the Department of Nutrition in the Gillings School of Global Public Health and in the UNC School of Medicine, a logical and well-placed home for a GCMD training grant. Nutrition science integrates “omics” (e.g., genomics, proteomics, metabolomics), behavioral, and population approaches and data to understand complex pathobiological processes and underlying causes of population health differences in GCMD, thus providing a strong platform for training translational global researchers in this field. Our program is co-directed by two senior faculty with strong mentoring records and extensive global experience and leadership in GCMD research. The program is guided by an internal training committee and an external advisory board. Our 22 UNC training faculty are scientists with substantial research support, excellent publication records across a wide range of disciplines, and strong mentoring experience. We request support for 5 predoctoral trainees per year. Trainees complete the PhD in nutrition and GCMD program-specific requirements, including specialized courses in global health and cardiovascular disease and options for in-depth training in (1) specialized methods important for GCMD, (2) translational medicine, or (3) implementation science. All trainees participate in a seminar led by the program directors, mentored research practicums, training in the responsible conduct of research, and mentoring for professional development, including submitting an NIH-style predoctoral and/or F award or similar application for extramural funding, and unique global internships with 15 global mentors who are exceptional CMD researchers working at 13 top universities or research centers in 11 countries. Our training program stands out because of its: (1) focus on nutrition, a major etiologic factor in the global disease burden; (2) life course approach to addressing GCMD; (3) interdisciplinary focus on causes ranging from cellular and molecular to whole organism and accounting for underlying social, economic, political, and environmental determinants; (4) emphasis on integration and translation of basic knowledge and discoveries from nutrition biochemistry, physiology, genetics, and epidemiology, to behavioral and environmental approaches and policies; and (5) outstanding faculty mentors who serve as role models for excellence in GCMD research and leaders working with countries to implement and evaluate large-scale regulatory efforts to prevent cardiometabolic disease. The program is training future leaders in GCMD research.

摘要 我们建议更新我们的全球心脏代谢疾病（GCMD）博士前培训计划。这个十字架- 一个以营养为重点的学科计划提供专门的培训，以培养一支研究人员队伍， 可以弥合基础，转化和人口科学，以减少日益增长的负担和差距， GCMD。低收入和中等收入国家迫切需要减轻这一负担，因为 这些国家受到的影响尤其严重，最需要更专业的技能和全球领导力。的 该培训项目由Gillings全球公共卫生学院营养系管理 在芝加哥医学院，一个合乎逻辑和良好的安置家庭为GCMD培训补助金。营养 科学整合了“组学”（例如，基因组学、蛋白质组学、代谢组学）、行为学和人口学 方法和数据，以了解复杂的病理生物学过程和根本原因的人口 GCMD中的健康差异，从而为培训翻译全球研究人员提供了一个强大的平台， 该领域我们的计划是由两名资深教师共同指导，具有强大的指导记录和广泛的 在GCMD研究方面的全球经验和领导地位。该计划由内部培训指导 委员会和外部咨询委员会。我们的22名培训教师都是科学家， 研究支持，跨学科的优秀出版记录，以及强有力的指导 体验.我们要求每年为5名博士前培训生提供支持。学员完成营养学博士学位 和GCMD计划的具体要求，包括全球卫生和 心血管疾病和选择深入培训（1）专业方法重要的GCMD，（2） 转化医学，或（3）实施科学。所有学员参加由该计划领导的研讨会 主任，指导研究实习，在负责任的研究行为的培训，并指导 专业发展，包括提交NIH风格的博士预科和/或F奖或类似的 申请校外资助，以及与15位杰出的全球导师一起进行独特的全球实习 CMD研究人员在11个国家的13所顶尖大学或研究中心工作。我们的培训计划 突出的原因是：（1）关注营养，这是全球疾病负担的一个主要病因;（2）生命 课程方法来解决GCMD;（3）跨学科的重点，从细胞和 从分子到整个有机体，并解释潜在的社会、经济、政治和环境 决定因素;（4）强调营养学基础知识和发现的整合和转化 生物化学，生理学，遗传学和流行病学，行为和环境方法， 政策;和（5）优秀的教师导师谁作为榜样，卓越的GCMD研究 领导人与各国合作，实施和评估大规模的监管工作， 心脏代谢疾病该计划正在培养GCMD研究的未来领导者。

项目成果

Snacking patterns among Chilean children and adolescents: is there potential for improvement?

• DOI: 10.1017/s1368980019000971
• 发表时间: 2019-10-01
• 期刊: PUBLIC HEALTH NUTRITION
• 影响因子: 3.2
• 作者: Jensen, Melissa L.;Corvalan, Camila;Taillie, Lindsey Smith
• 通讯作者: Taillie, Lindsey Smith

Food Vendors and the Obesogenic Food Environment of an Informal Settlement in Nairobi, Kenya: a Descriptive and Spatial Analysis.

肯尼亚内罗毕非正式定居点的食品供应商和致肥胖食品环境：描述性和空间分析。

• DOI: 10.1007/s11524-022-00687-7
• 发表时间: 2023
• 期刊: Journal of urban health : bulletin of the New York Academy of Medicine
• 作者: Busse,KyleR;Logendran,Rasheca;Owuor,Mercy;Omala,Hillary;Nandoya,Erick;Ammerman,AliceS;Martin,StephanieL
• 通讯作者: Martin,StephanieL

Community-Engaged Bidirectional Crisis and Emergency Risk Communication With Immigrant and Refugee Populations During the COVID-19 Pandemic.

• DOI: 10.1177/00333549211065514
• 发表时间: 2022-03
• 期刊: Public health reports (Washington, D.C. : 1974)
• 作者: Wieland ML;Asiedu GB;Njeru JW;Weis JA;Lantz K;Abbenyi A;Molina L;Ahmed Y;Osman A;Goodson M;Torres-Herbeck G;Nur O;Porraz Capetillo G;Mohamed AA;Sia IG
• 通讯作者: Sia IG

Prevention Research Centers and COVID-19: Models of a Community-Engaged Response to a Public Health Emergency.

• DOI: 10.1177/00333549211059491
• 发表时间: 2022-03
• 期刊: Public health reports (Washington, D.C. : 1974)
• 作者: Busse KR;Lemon SC;Comerford BP;Islam NS;Ulin BF;Eriksen MP;Ammerman AS
• 通讯作者: Ammerman AS