Eating, Activity, and Weight-Related Problems Across the Life Course in Diverse Populations

总结/摘要 肥胖和其他与体重有关的问题，包括饮食摄入不足，身体活动不足， 不满意和饮食失调的行为是主要的公共卫生问题，因为他们的高 流行和严重的健康后果。这些问题在年轻人中的高发病率， 低收入和少数民族/种族群体尤其令人关切。该研究计划旨在确定 多层次的因素影响着整个生命关键阶段的广泛的体重相关问题 课程，以指导发展高度创新的，文化上可接受的，有效的干预措施， 最需要的人群。重点将放在从青春期到成年的过渡， 研究不足，但重要的是，生活时期的发展体重问题。这项研究计划是 旨在实现首席研究员的愿景，使来自各种背景的年轻人都能 积极的体重相关的健康，从他们的家人，朋友，学校，工作场所和社区的支持。 这个杰出的研究者奖（R35-OIA）将支持一个高生产力和有效的研究人员 和她的团队的方式，将促进创造力，允许战略冒险，并有很大的影响， 与体重有关的问题。该研究计划结合了长期和明确的队列研究， 一个灵活的计划，以解决新出现的感兴趣的主题。该研究计划建立和扩展在 项目EAT（青少年和年轻人的饮食和活动）研究，最大和最全面的 一项纵向研究，检查了与体重相关的广泛问题的多层次预测因素， 年轻人研究方案将包括以下内容：1）12年纵向、多层次随访 从年轻人（N= 2，793）及其家庭的不同样本中收集有关体重相关问题的数据， 朋友、学校、工作场所和邻里环境; 2）中间和快速反应调查 捕捉短期变化并评估社会变化和新政策影响的机制 与体重相关结果的潜在相关性; 3）使用多种方法进行深入研究的创新子研究 探索多层次的病因学过程，以指导干预措施的制定;以及4）指导培训 该计划为新的研究人员谁将塑造年轻成人体重相关的健康领域的未来。 这OIA的研究综合方案将导致多层次的解释发展 青年人体重相关问题模型和高危人群干预措施。 一个强有力的培训计划的整合将确保下一代公共卫生专业人员 防止边缘化人群继续承受体重相关问题的负担的工具。 因此，这项研究计划建立在NHLBI战略愿景的基础上，特别是关于目标：1） 调查人口之间健康差异的因素; 2）发展，多样化， 维持一支能够完成NHLBI使命的科学队伍。

SUMMARY/ABSTRACT Obesity and other weight-related problems, including poor dietary intake, inadequate physical activity, body dissatisfaction, and disordered eating behaviors, are of major public health concern, given their high prevalence and serious health consequences. The high prevalence of these problems in young people from low-income and ethnic/racial minority groups is of particular concern. This program of research aims to identify multi-level factors influencing a broad range of weight-related problems throughout key stages of the life course to guide the development of highly innovative, culturally acceptable, and effective interventions for populations in greatest need. The focus will be on the transition from adolescence to adulthood, an understudied, but important, period of life for the development of weight problems. This program of research is aimed at achieving the Principal Investigator's vision whereby young people from all backgrounds will have positive weight-related health, with support from their family, friends, schools, worksites, and neighborhoods. This Outstanding Investigator Award (R35-OIA) will support a highly productive and effective researcher and her team in a manner that will promote creativity, allow strategic risk-taking, and have a great impact on weight-related problems. The program of research combines a longstanding and well-defined cohort study with a flexible plan to address emerging topics of interest. The research program builds and expands upon the Project EAT (Eating and Activity in Teens and Young Adults) studies, the largest and most comprehensive longitudinal body of research examining multi-level predictors of a broad range of weight-related problems in young people. The research program will include the following: 1) 12-year longitudinal, multi-level follow-up data collection on weight-related problems from a diverse sample of young people (N=2,793) and their family, friend, school, worksite, and neighborhood environments; 2) intermediate and rapid response survey mechanisms to capture short-term changes and assess the impact of societal changes and emerging policies of potential relevance to weight-related outcomes; 3) innovative substudies using multiple methods for in-depth explorations of multi-level etiological processes to guide intervention development; and 4) a mentored training program for new investigators who will shape the future of the field of young adult weight-related health. This OIA comprehensive program of research will lead to the development of multi-level explanatory models for weight-related problems in young people and interventions for populations at greatest risk. Integration of a strong training program will ensure that the next generation of public health professionals has the tools to prevent marginalized populations from continuing to carry the burden of weight-related problems. Thus, this program of research builds on the NHLBI Strategic Vision, particularly regarding the objectives: 1) to investigate factors that account for differences in health among populations; and 2) to develop, diversify, and sustain a scientific workforce capable of accomplishing NHLBI's mission.