Administrative Core: Center for Diagnostic and Therapeutic Strategies in Pancreatic Cancer

行政核心：胰腺癌诊断和治疗策略中心

• 批准号: 10666692
• 负责人: Sanku Mallik
• 金额: $ 56.22万
• 依托单位: NORTH DAKOTA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10666692
• 关键词: Acceleration; Address; Advisory Committees; American Association of Cancer Research; American Cancer Society; Animal Model; Biomedical Research; Budgets; Cancer Biology; Cell model; Clinical; Collaborations; Core Facility; Dedications; Department of Defense; Diagnostic; Disease; Educational workshop; Ensure; Environment; Equilibrium; Equipment; Experimental Designs; Extramural Activities; Faculty; Family; Fostering; Foundations; Funding; Funding Mechanisms; Goals; Grant; Infrastructure; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Manuscripts; Mentors; Modeling; National Institute of General Medical Sciences; North Dakota; Organization and Administration; Peer Review; Personnel Management; Persons; Phase; Pilot Projects; Preparation; Process; Published Comment; R24; Recommendation; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Science; Scientist; Secure; Senior Scientist; Services; Strategic Planning; Structure; Technical Expertise; Therapeutic; Training; Translational Research; United States National Institutes of Health; Universities; Work; Writing; career; career development; competitive environment; improved; meetings; member; operation; organizational structure; peer; programs; recruit; skills; success; symposium; translational scientist; translational study; virtual

Project Summary: The administrative core will oversee the coordination of the "Center for Diagnostic and Therapeutic Strategies in Pancreatic Cancer" (CDTSPC). It will provide essential resources to administer the organizational structure and ensure the success of CDTSPC at North Dakota State University (NDSU). The Center will continue to develop research programs led by Junior Investigators, promote biomedical translational research, enhance the research infrastructure at NDSU, and provide enhanced mentoring to increase the number of NIH-funded research grants. The goals of this Center are to develop self-sustaining research programs by Junior Investigators, increase the number of NIH-funded researchers, and expand the University's research capability on a disease-specific program, particularly in pancreatic cancer. These goals will be accomplished through the following Specific Aims. Aim 1: Continue to provide efficient leadership and administrative structure for the successful operations of CDTSPC. The Administrative Core will ensure that the Junior Investigators are supported by all Core Facilities and equipment needed to ensure rapid research progress. The Center will conduct formative and summative assessments of all projects, Core Facilities, and the career development-mentoring plan. In addition, the Administrative Core will be responsible for budget management, External Advisory Committee (EAC) meetings, symposia, and yearly reports to NIGMS. Aim 2: Implement an enhanced, result-oriented, multi-tier mentoring strategy to accelerate the career development of the Junior Investigators. The Administrative Core will implement an enhanced mentoring model that identifies two external and one internal mentor and one peer advisor (mentoring team) for each Junior Investigator. The mentoring team will address future research directions, organization and presentation of manuscripts, strategies for writing competitive proposals, and proposal review before submission. Furthermore, Junior Investigators will engage with CDTSPC's Translational Science Liaison and receive mentoring on the translational aspects of their projects. Aim 3: Enhance biomedical research infrastructure at NDSU. The Administrative Core will competitively recruit a replacement once a Junior Investigator graduates as an independent investigator through a campus-wide proposal solicitation, external peer review, recommendation of the EAC, followed by NIH approval. Aim 4: Accomplish the self-sustaining status of CDTSPC. All investigators will compete for extramural research grants from federal and non-federal resources in the competitive field of cancer biology. In addition, the Administrative core will ensure timely completion of the CDTSPC milestones.

项目概要： 行政核心将监督协调“诊断和治疗战略中心， 胰腺癌（CDTSPC）。它将为管理组织结构提供必要的资源， 确保CDTSPC在北达科他州州立大学（NDSU）的成功。中心将继续发展 由初级研究员领导的研究项目，促进生物医学转化研究，加强研究 NDSU的基础设施，并提供加强的指导，以增加NIH资助的研究赠款的数量。 该中心的目标是通过初级研究人员开发自我维持的研究计划，增加 美国国立卫生研究院资助的研究人员的数量，并扩大大学的研究能力，对疾病的具体 特别是在胰腺癌方面。这些目标将通过以下具体措施实现： 目标。目标1：继续为成功的行动提供有效的领导和行政结构 关于CDTSPC行政核心将确保初级研究者得到所有核心设施的支持 以及确保快速研究进展所需的设备。该中心将进行形成性和总结性的 对所有项目、核心设施和职业发展辅导计划进行评估。此外该 行政核心将负责预算管理、外部咨询委员会会议， 专题讨论会和向NIGMS提交的年度报告。目标2：实施强化的、注重成果的多层次辅导 加速初级调查员职业发展的战略。行政核心将执行 一个增强的指导模式，确定两个外部和一个内部导师和一个同行顾问 （指导团队）。指导小组将讨论未来的研究方向， 组织和展示稿件，撰写竞争性提案的策略，以及提案审查 在提交之前。此外，初级研究者将参与CDTSPC的转化科学联络 并接受项目翻译方面的指导。目标3：加强生物医学研究 NDSU的基础设施。行政核心将竞争性地招聘一个替代者， 研究员通过全校范围内的外部提案征集毕业，成为独立研究员 同行评审，EAC推荐，然后NIH批准。目标4：实现自我维持 CDTSPC的现状。所有的研究人员都将从联邦和非联邦的校外研究赠款竞争 在竞争激烈的癌症生物学领域的资源。此外，行政核心将确保及时 完成CDTSPC里程碑。