Developmental Core

发展核心

• 批准号: 10669172
• 负责人: Andrew Ddungu Kambugu
• 金额: $ 22.1万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-13 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10669172
• 关键词: AIDS related cancer; Address; Africa; Africa South of the Sahara; African; Age; Area; Award; Back; California; Caring; Clinical Research; Communicable Diseases; Country; Development; Doctor of Philosophy; Early Diagnosis; Environment; Funding; Future; Generations; Grant; HIV; Health Sciences; Home; Individual; Institution; International; Junior Physician; K-Series Research Career Programs; Leadership; Learning; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentors; Mentorship; Methodology; Modeling; Molds; Pattern; Phase; Pilot Projects; Prevention; Principal Investigator; Process; Productivity; Research; Research Methodology; Research Personnel; Research Project Grants; Research Support; Resources; San Francisco; Scientist; Stream; Time; Training; Translational Research; Uganda; United States; United States National Institutes of Health; Universities; Wages; Writing; anticancer research; career; career development; cohort; college; epidemiology study; experience; improved; interest; knowledge base; programs; prospective; response; skills; virus related cancer

Creating an independent scientist requires extensive training within an enriching academic environment as well as adequate salary and research support for the trainee. The period that follows didactic graduate training is particularly vulnerable in East Africa, which is also true in sub-Saharan Africa as a whole. While funding streams exist for graduate training, the region lacks comprehensive mechanisms to support junior investigators as they transition towards research independence. In the U.S., post-graduate training is often facilitated by NIH "K Award" programs at both the individual and institutional level. NIH K Awards had been unavailable to African scientists but this recently changed with the creation of the K43 Emerging Global Leader Award. Yet, there still remains a substantial challenge preparing both trainees and their home institutions to compete for a K43 Award or other career development awards. To address the need for career development in the post-graduate period, the Developmental Core of the USEAHAMRC will: Aim 1. Bolster the overall environment for career development in clinical, epidemiologic and translational research at the East African institutions of our United States-East Africa HIV- Associated Malignancy Research Center (USEAHAMRC). Aim 2. Mentor and provide protected time for our emerging African and U.S. junior scientists working in the field of HIV-associated malignancies as they develop their academic and leadership portfolio and mature towards independence. Aim 3. Award funding for pilot research projects to be conducted by emerging African or U.S scientists. Modeled on institutional K Award programs in the U.S., we will create a semi-monthly Career Development Seminar featuring emphasis on scientific writing, mentorship skills, and foundational methodologic training for all interested scholars at our participating institutions (Aim 1). By drawing upon lessons learned from K Award funding in the U.S., four emerging Ugandan principal investigators will have a substantial portion of their time supported for the conduct of research in area of HIV-associated malignancies and will be mentored to compete for funding that will propel them to the next stage of their careers (Aim 2). With the assistance from substantial institutional commitment from UCSF, we will award two or three Pilot Project Awards annually over the 5-year funding cycle for research related to the USEAHAMRC research themes, which will help us identify and mentor the next cohort of junior investigators.

培养一名独立的科学家需要在丰富的学术环境中进行广泛的培训， 并为受训者提供足够的工资和研究支持。接下来的一段时间， 培训在东非尤其脆弱，整个撒哈拉以南非洲也是如此。而 研究生培训存在资金流，但该区域缺乏支持初级教育的综合机制， 研究人员向研究独立过渡。在美国，研究生培训往往是 在个人和机构层面上，由NIH“K奖”计划提供便利。NIH K奖已经 非洲科学家无法获得，但最近随着K43新兴全球的创建， 领袖奖。然而，仍然存在着一个巨大的挑战，准备学员和他们的家 机构竞争K43奖或其他职业发展奖项。为了满足 在研究生阶段的职业发展，USEAHAMRC的发展核心将： 目标1.支持职业发展的整体环境，在临床，流行病学和 在我们美国东非艾滋病毒研究所进行的转化研究， 美国联合研究中心（USEAHAMRC）。 目标二。为我们新兴的非洲和美国年轻科学家提供指导和保护时间 在艾滋病毒相关的恶性肿瘤领域工作，因为他们发展自己的学术和 领导组合和走向独立的成熟。 目标3.为新兴非洲国家或美国进行的试点研究项目提供奖励资金 科学家 仿照美国的K奖项目，我们将创建一个半月的职业发展 研讨会强调科学写作，指导技能和基础方法训练 为所有有兴趣的学者在我们的参与机构（目标1）。通过吸取K 在美国，四名新出现的乌干达主要调查人员将有相当大的一部分， 他们的时间支持在艾滋病毒相关恶性肿瘤领域进行研究，并将 指导他们竞争资金，这将推动他们进入职业生涯的下一个阶段（目标2）。与 在加州大学旧金山分校的大量机构承诺的帮助下，我们将授予两个或三个试点项目 在5年的资助周期内，每年为与USEAHAMRC研究主题相关的研究颁发奖项， 这将帮助我们识别和指导下一批初级调查员。