Geriatric Oncology Research Infrastructure to Improve Clinical Care

改善临床护理的老年肿瘤学研究基础设施

基本信息

  • 批准号:
    10667860
  • 负责人:
  • 金额:
    $ 66.96万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-04-01 至 2028-06-30
  • 项目状态:
    未结题

项目摘要

ABSTRACT The overall goal of this five year R33 grant proposal, “Geriatric Oncology Research Infrastructure to Improve Clinical Care,” submitted on behalf of the Cancer and Aging Research Group (CARG; mycarg.org), is to further expand CARG’s national research infrastructure to support innovative investigators, leaders, and projects to answer significant interdisciplinary research questions at the aging and cancer interface. This proposal, in response to PAR 20-071, supports “advanced-stage development and utilization of novel research infrastructure to advance the science of aging in specific areas requiring interdisciplinary partnerships or collaborations.” Even after creating a robust aging and cancer research infrastructure over the last five years through the R21/33 mechanism, there remains substantial unmet need to expand this infrastructure to develop high-impact research at the aging and cancer interface. The overall goal remains to significantly and rapidly improve the lives of older adults with cancer through scholarship and leadership by expanding CARG’s impact. With the support of the R21/33 mechanism, the multiple Principal Investigators (MPI: Dale, Mohile, Hurria/Klepin) completed a coordinated, broad-based strategy to infuse aging principles into oncology research. Through the original grant’s Aims, CARG has become a recognized international leader for mentorship and scholarship in aging and cancer. CARG is a coalition of aging and cancer scholars dedicated to: 1) connecting interdisciplinary investigators together; 2) designing, implementing, and disseminating aging and cancer research; 3) mentoring new interdisciplinary investigators in the field; and 4) disseminating and advocating for equitable research and care for older adults. In exceeding the aims of the R21/R33 award, CARG successfully transitioned from infrastructure development (R21) to establishment (R33), centering around six Cores and a Leadership Team. This R33 renewal is sought to expand CARG’s impact through the following Aims: 1) Expand the reach of the infrastructure, using the Cores, to facilitate the design and rigor of CARG’s aging and cancer research; 2) Facilitate high-priority, impactful research at the interface of aging and cancer through pilot awards and the conduct of large, competitive multi-site studies; 3) Identify, cultivate, and mentor CARG investigators for leadership in aging and cancer research to develop the next generation of leaders in the field; 4) Build greater capacity for engagement with older patients with cancer and caregivers through CARG’s patient advocacy group (SCOREboard) to further grow patient-centered aging and cancer research; and 5) Develop and disseminate geriatric oncology-specific content including best clinical practices, research findings, and opportunities for collaboration and advocacy through a robust communication strategy. Ultimately, the proposed activities will substantially expand CARG’s infrastructure to advance high-impact research aimed at improving the care of older adults with cancer globally.
摘要 这项为期五年的R33拨款提案的总体目标是,改善老年肿瘤学研究基础设施 代表癌症和老龄化研究小组(Carg;mycarg.org)提交的《临床护理》是 进一步扩大CAG的国家研究基础设施,以支持创新的调查人员、领导者、 和项目,以回答老龄化和癌症方面的重大跨学科研究问题 界面。根据标准杆20-071的要求,这项建议支持“高级阶段的开发和利用 在需要跨学科的特定领域推进老龄化科学的新型研究基础设施 合作伙伴关系或合作关系。即使在创建了强大的老龄化和癌症研究基础设施之后 在过去五年中,通过R21/33机制,仍有大量需求未得到满足 扩大这一基础设施,以发展在老龄化和癌症界面上的高影响力研究。这个 总体目标仍然是通过以下方式显著和迅速改善患有癌症的老年人的生活 通过扩大CAG的影响力而获得学术和领导力。在R21/33机制的支持下, 多名首席调查员(MPI:Dale、Mohile、Hurria/Klepin)完成了一项协调、基础广泛的 将衰老原理注入肿瘤学研究的策略。通过最初拨款的目标,Carg已经 成为在老龄化和癌症领域的导师和奖学金方面公认的国际领导者。卡格是一个 老龄化和癌症学者联盟致力于:1)将跨学科研究人员联系在一起;2) 设计、实施和传播衰老和癌症研究;3)指导新的跨学科 4)传播和倡导对老年人的公平研究和照顾。 在超过R21/R33奖项的目标的过程中,CAG成功地从基础设施开发过渡到 (R21)到建立(R33),以六个核心和一个领导团队为中心。此次R33续订是 寻求通过以下目标扩大CAG的影响:1)扩大基础设施的覆盖范围, 使用核心,以促进CAG的衰老和癌症研究的设计和严谨;2)促进高优先级, 通过试点奖项和开展大型竞争性研究,在老龄化和癌症的界面上进行有影响力的研究 多点研究;3)确定、培养和指导CAG研究人员在衰老和癌症研究方面的领导作用 培养该领域的下一代领导者;4)增强与老年患者接触的能力 通过Carg的患者权益倡导小组(记分板)与癌症和护理人员合作,进一步发展以患者为中心 老龄化和癌症研究;5)开发和传播针对老年肿瘤学的内容,包括BEST 临床实践、研究结果以及通过强大的 沟通策略。最终,拟议的活动将大幅扩展CAG的基础设施,以 推进高影响力研究,旨在改善全球癌症老年患者的护理。

项目成果

期刊论文数量(8)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Risk Factors for Hospitalizations Among Older Adults with Gastrointestinal Cancers.
患有胃肠癌的老年人住院的危险因素。
  • DOI:
    10.1093/oncolo/oyab016
  • 发表时间:
    2022-02-03
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Li D;Sun CL;Allen R;Crook CJ;Levi A;Ballena R;Klepin HD;Elias R;Mohile SG;Tew WP;Owusu C;Muss HB;Lichtman SM;Gross CP;Chapman AE;Gajra A;Cohen HJ;Katheria V;Hurria A;Dale W
  • 通讯作者:
    Dale W
Visitation policies at NCI-designated comprehensive cancer centers during the COVID-19 pandemic.
Improving personalized treatment decision-making for older adults with cancer: The necessity of eliciting patient preferences.
  • DOI:
    10.1016/j.jgo.2021.06.001
  • 发表时间:
    2022-01
  • 期刊:
  • 影响因子:
    3
  • 作者:
    Richardson DR;Loh KP
  • 通讯作者:
    Loh KP
Adaptation of Serious Illness Care Program to be delivered via telehealth for older patients with hematologic malignancy.
  • DOI:
    10.1182/bloodadvances.2022008996
  • 发表时间:
    2023-05-09
  • 期刊:
  • 影响因子:
    7.5
  • 作者:
    LoCastro, Marissa;Sanapala, Chandrika;Mendler, Jason H.;Norton, Sally;Bernacki, Rachelle;Carroll, Thomas;Klepin, Heidi D.;Watson, Erin;Liesveld, Jane;Huselton, Eric;O'Dwyer, Kristen;Baran, Andrea;Flannery, Marie;Kluger, Benzi;Loh, Kah Poh
  • 通讯作者:
    Loh, Kah Poh
Study design and methods for the using exercise to relieve joint pain and improve AI adherence in older breast cancer survivors (REJOIN) trial.
  • DOI:
    10.1016/j.jgo.2021.05.011
  • 发表时间:
    2021-09
  • 期刊:
  • 影响因子:
    3
  • 作者:
    Bluethmann SM;Truica C;Klepin HD;Olsen N;Sciamanna C;Chinchilli VM;Schmitz KH
  • 通讯作者:
    Schmitz KH
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WILLIAM DALE其他文献

WILLIAM DALE的其他文献

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{{ truncateString('WILLIAM DALE', 18)}}的其他基金

Geriatric Oncology Research Infrastructure to Improve Clinical Care
改善临床护理的老年肿瘤学研究基础设施
  • 批准号:
    10180832
  • 财政年份:
    2020
  • 资助金额:
    $ 66.96万
  • 项目类别:
Geriatric Oncology Research Infrastructure to Improve Clinical Care
改善临床护理的老年肿瘤学研究基础设施
  • 批准号:
    10385859
  • 财政年份:
    2020
  • 资助金额:
    $ 66.96万
  • 项目类别:
Geriatric Oncology Research Infrastructure to Improve Clinical Care
改善临床护理的老年肿瘤学研究基础设施
  • 批准号:
    10079691
  • 财政年份:
    2020
  • 资助金额:
    $ 66.96万
  • 项目类别:
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with Cancer
指导下一代老年肿瘤学研究人员进行以患者为导向的研究,以改善患有癌症的老年人的护理
  • 批准号:
    10300434
  • 财政年份:
    2017
  • 资助金额:
    $ 66.96万
  • 项目类别:
Mentoring the Next Generation of Geriatric Oncology Researchers in Patient-Oriented Research to Improve the Care of Older Adults with Cancer
指导下一代老年肿瘤学研究人员进行以患者为导向的研究,以改善患有癌症的老年人的护理
  • 批准号:
    10066298
  • 财政年份:
    2017
  • 资助金额:
    $ 66.96万
  • 项目类别:
Mentoring the Next Generation of Geriatric Oncology and Supportive Care Researchers in Patient-Oriented Research to Improve the Care of Older Adults with Cancer
指导下一代老年肿瘤学和支持性护理研究人员进行以患者为导向的研究,以改善患有癌症的老年人的护理
  • 批准号:
    10807909
  • 财政年份:
    2017
  • 资助金额:
    $ 66.96万
  • 项目类别:
Geriatric Oncology: Educating nurses to improve quality care
老年肿瘤学:教育护士提高护理质量
  • 批准号:
    9751790
  • 财政年份:
    2015
  • 资助金额:
    $ 66.96万
  • 项目类别:
Utility-Assessment for Co-Morbidities in Prostate Cancer
前列腺癌合并症的效用评估
  • 批准号:
    7896345
  • 财政年份:
    2010
  • 资助金额:
    $ 66.96万
  • 项目类别:
Utility-Assessment for Co-Morbidities in Prostate Cancer
前列腺癌合并症的效用评估
  • 批准号:
    8103892
  • 财政年份:
    2010
  • 资助金额:
    $ 66.96万
  • 项目类别:
Emotions in Medical Decision Making in Older Adults
老年人医疗决策中的情绪
  • 批准号:
    6838109
  • 财政年份:
    2004
  • 资助金额:
    $ 66.96万
  • 项目类别:

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