Integrative Molecular Epidemiology Workshop

项目摘要 美国癌症研究协会(AACR)寻求NCI重新支持 为期一周的创新、独特和密集的教育体验(集成分子 流行病学研讨会)。研讨会的前提是快速将大数据从 不断发展的改善癌症预防和患者预后的“组学”技术不能仅仅 可通过随机对照临床试验实现。因此，研讨会的重点是 在流行病学框架内应用这些技术。特别的 重要的是需要教育癌症研究人员灵活地整合不同的高水平的 维度分子数据，在这样做的时候要意识到风险和陷阱，并有技能 以及对结果进行适当解释和应用的能力。因此，所有的车间 讲座和实验室认识到诸如可行性、可扩展性、质量控制、 研究设计，以及实践的局限性。 该研讨会主要面向分子流行病学家，但材料是 设计也适用于遗传学家、统计学家、生物信息学家、分子 生物学家、内科科学家和其他在 流行病学。聚集在一起教授这次研讨会的高素质教职员工拥有 跨越这些学科，确保所有材料都是最高质量的。基于我们的 经验，我们预计申请过程将非常有竞争力，数量是 申请可供选择的空位。预计50名与会者中的大多数将是 博士后研究员和初级教员，但高级研究生和中高级/高级 教职员工将有资格参加。 讲座采用互动教学和合作小组学习的方式， 补充了专注于方法的实际应用的实验室和 动手使用网上可用的工具和资源。车间里点缀着应用软件。 来自该领域领导者的研究研讨会，他们展示了使用 课程中介绍的方法。工作午餐辅导课程涵盖职业发展 主题。为了提供团队科学的真实体验，我们将参与者组织成 五人跨学科小组，并指导他们进行合作小组学习。最后，我们 使用每个演示文稿、每天、整体的可测量结果评估学习 车间在完工后立即完成，并随时间推移。AACR拥有经验丰富的员工和 在管理教育研讨会方面有出色的记录。

Project Summary The American Association for Cancer Research (AACR) seeks a renewal of NCI support for an innovative, unique, and intensive one-week educational experience (Integrative Molecular Epidemiology Workshop). The workshop’s premise is that the translation of big data from rapidly evolving “omics” technologies to improve cancer prevention and patient outcomes cannot solely be achieved through randomized controlled clinical trials. As such, the focus of the workshop is the application of these technologies within an epidemiologic framework. Of particular importance is the need to educate cancer researchers to be facile in integrating diverse high- dimensional molecular data, be aware of the risks and pitfalls when doing so, and have the skills and competence for proper interpretation and application of the results. Thus, all workshop lectures and laboratories are cognizant of issues such as feasibility, scalability, quality control, study design, and practical limitations. The workshop is primarily targeted toward molecular epidemiologists, but the materials are designed to also be appropriate for geneticists, statisticians, bioinformaticians, molecular biologists, physician-scientists, and others who have completed basic coursework in epidemiology. The highly qualified faculty assembled to teach this workshop have expertise that spans these disciplines ensuring that all materials are of the highest quality. Based on our experience, we expect the application process to be highly competitive, with twice the number of applications for the slots available. It is expected that the majority of the 50 attendees will be postdoctoral fellows and junior faculty, but advanced graduate students and mid-level/senior faculty will be eligible to participate. The lectures, which use interactive teaching and cooperative group learning approaches, are supplemented with laboratories that focus on practical application of the methods and hands-on use of tools and resources available online. The workshop is interspersed with applied research seminars from leaders in the field who showcase cutting-edge science using the methods introduced in the course. Working lunch mentoring sessions cover career development topics. To provide real-life experience in team science, we organize the participants into interdisciplinary groups of five, and instruct them on cooperative group learning. Finally, we evaluate learning with measurable outcomes for each presentation, each day, the overall workshop immediately after completion, and over time. AACR has experienced staff and an excellent track record for administering educational workshops.