Integrative Molecular Epidemiology Workshop

项目摘要 美国癌症研究协会（AACR）寻求更新NCI对以下方面的支持： 一个创新的，独特的，和密集的一周的教育经验（整合分子 流行病学研讨会）。研讨会的前提是，大数据的翻译从迅速 不断发展的“组学”技术，以改善癌症预防和患者的结果，不能仅仅 通过随机对照临床试验实现。因此，研讨会的重点是 这些技术在流行病学框架内的应用。特别 重要的是需要教育癌症研究人员，使他们能够轻松地整合各种高水平的 三维分子数据，在这样做时要意识到风险和陷阱，并拥有技能 以及正确解释和应用结果的能力。因此，所有车间 讲座和实验室认识到的问题，如可行性，可扩展性，质量控制， 研究设计和实际限制。 该研讨会主要针对分子流行病学家，但材料是 也适用于遗传学家、统计学家、生物信息学家、分子生物学家、 生物学家，物理学家，科学家和其他已经完成基础课程的人， 流行病学高素质的教师聚集在一起教这个讲习班有专业知识， 跨越这些学科，确保所有材料的最高质量。基于我们 经验，我们预计申请过程将具有高度竞争力， 应用程序的插槽可用。预计50名与会者中的大多数将是 博士后研究员和初级教师，但高级研究生和中级/高级 教师将有资格参加。 讲座采用互动教学和合作小组学习方法， 补充实验室，侧重于实际应用的方法， 动手使用在线工具和资源。研讨会穿插着应用 来自该领域领导者的研究研讨会，他们使用 在课程中介绍的方法。工作午餐辅导课程涵盖职业发展 话题为了提供团队科学的真实体验，我们将参与者组织成 跨学科的五个小组，并指导他们合作小组学习。最后我们 评估学习与可衡量的成果，为每个演示，每一天，整体 车间完工后立即，并随着时间的推移。AACR拥有经验丰富的员工和 管理教育工作坊的良好记录。

Project Summary The American Association for Cancer Research (AACR) seeks a renewal of NCI support for an innovative, unique, and intensive one-week educational experience (Integrative Molecular Epidemiology Workshop). The workshop’s premise is that the translation of big data from rapidly evolving “omics” technologies to improve cancer prevention and patient outcomes cannot solely be achieved through randomized controlled clinical trials. As such, the focus of the workshop is the application of these technologies within an epidemiologic framework. Of particular importance is the need to educate cancer researchers to be facile in integrating diverse high- dimensional molecular data, be aware of the risks and pitfalls when doing so, and have the skills and competence for proper interpretation and application of the results. Thus, all workshop lectures and laboratories are cognizant of issues such as feasibility, scalability, quality control, study design, and practical limitations. The workshop is primarily targeted toward molecular epidemiologists, but the materials are designed to also be appropriate for geneticists, statisticians, bioinformaticians, molecular biologists, physician-scientists, and others who have completed basic coursework in epidemiology. The highly qualified faculty assembled to teach this workshop have expertise that spans these disciplines ensuring that all materials are of the highest quality. Based on our experience, we expect the application process to be highly competitive, with twice the number of applications for the slots available. It is expected that the majority of the 50 attendees will be postdoctoral fellows and junior faculty, but advanced graduate students and mid-level/senior faculty will be eligible to participate. The lectures, which use interactive teaching and cooperative group learning approaches, are supplemented with laboratories that focus on practical application of the methods and hands-on use of tools and resources available online. The workshop is interspersed with applied research seminars from leaders in the field who showcase cutting-edge science using the methods introduced in the course. Working lunch mentoring sessions cover career development topics. To provide real-life experience in team science, we organize the participants into interdisciplinary groups of five, and instruct them on cooperative group learning. Finally, we evaluate learning with measurable outcomes for each presentation, each day, the overall workshop immediately after completion, and over time. AACR has experienced staff and an excellent track record for administering educational workshops.