Prevention And Control of Cancer: Training for Change in Individuals and Systems

摘要 此申请是NCI资助的实施科学培训计划的竞争性续签，由 马萨诸塞大学医学院，题为“PRACCTIS”(预防和控制癌症： 针对个人和系统中的变化的培训)。最初于2014年通过R25T机制提供资金，我们 寻求将这一成功的计划扩展为NCI资助的T32培训计划。有了新的资金，我们的 使命，培训下一代研究人员进行研究，以解决 将循证癌症预防和控制转化为马萨诸塞州和全国的实践，将 继续。我们通过努力实现三个总体规划目标来完成这一使命：1)促进 通过教育培养独立的癌症预防和控制实施科学家 为每个学员提供个性化的课程、充实机会和指导研究经验 并与不同的临床和社区合作伙伴合作进行；2)确定有效的 通过持续的计划监控和实施计划组件和实施计划改进 评估；以及3)通过方案广泛推进实施科学领域的培训 评估和传播创新的方案组成部分和最佳做法。建议的T32 该方案利用并扩大了在上一个供资周期中开发的现有培训基础设施， 包括实施科学、充实机会、以团队科学为导向的结构化课程 指导，以及严格的项目监测和评估计划。我们还将继续强调 利益相关者参与的研究与当地临床和社区环境合作进行 癌症防治治疗和干预措施。在我们严格的计划评估的推动下，我们的 该计划将在这次竞争续签中得到重要的加强。首先，我们将创建个性化的 实施研究的关键领域的培训途径被我们的学员确定为优先事项 上一个周期以及整个实地都是如此。这些途径是在健康信息学、健康 在资源匮乏的环境中进行沟通和干预。第二，引入更多的教师专业知识 在这些领域，我们已经扩大了我们的导师库，包括来自当地机构的专家，这些专家成功地 合作历史，包括波士顿大学、伍斯特理工学院、马萨诸塞州大学贝州分校和 退伍军人健康管理局贝德福德和波士顿校区。与这些导师的关系 校园是在我们之前的资助周期中启动的，将在这次竞争性续签中正式启动。我们 将进一步扩展PRACCTIS，以包括博士后和博士后实习生。PRACCTIS将 在接下来的五年资助期内招聘10名博士后和3名博士后实习生，从而产生 解决循证癌症预防翻译中的空白的独立调查人员队伍 并将控制治疗和干预措施付诸实践。

ABSTRACT This application is a competitive renewal of the NCI-funded Implementation Science training program led by the University of Massachusetts Medical School, entitled “PRACCTIS” (Prevention and Control of Cancer: Training for change in Individuals and Systems). Initially funded in 2014, through the R25t mechanism, we seek to extend this successful program as an NCI-funded T32 training program. With renewed funding, our mission, to train the next generation of researchers in the conduct of research that addresses gaps in the translation of evidence-based cancer prevention and control into practice in Massachusetts and nationally, will continue. We accomplish this mission by working toward three overarching programmatic goals: 1) To promote the development of independent cancer prevention and control implementation scientists through educational curricula, enrichment opportunities, and mentored research experiences that are personalized to each trainee and conducted in collaboration with a diverse range of clinical and community partners; 2) To identify effective program components and implement program improvements through a continuous program monitoring and evaluation; and 3) To broadly advance training in the field of implementation science through program evaluation and dissemination of innovative program components and best practices. The proposed T32 program leverages and expands the existing training infrastructure developed in the previous funding cycle, including structured courses in implementation science, enrichment opportunities, team science-oriented mentoring, and a rigorous program monitoring and evaluation plan. We will also continue to emphasize stakeholder-engaged research conducted in collaboration with local clinical and community settings that deliver cancer prevention and control treatments and interventions. Driven by our rigorous program evaluation, our program will be enhanced in this competitive renewal in important ways. First we will create personalized training pathways in areas critical areas of implementation research identified as priorities by trainees in our previous cycle as well as in the field at-large. These pathways are in the areas of health informatics, health communications and interventions in low resource settings. Second, to bring additional faculty expertise in these areas, we have extended our pool of mentors to include experts from local institutions with successful histories of collaboration, including UMass Boston, Worcester Polytechnic Institute, UMass-Baystate and the Bedford and Boston campuses of the Veterans Health Administration. Relationships with mentors from these campuses were initiated in our previous funding cycle and will be formalized in this competitive renewal. We will additionally extend PRACCTIS to include both pre-doctoral and post-doctoral trainees. PRACCTIS will recruit 10 post-doctoral and 3 pre-doctoral trainees over the next five year funding period, thus producing a cadre of independent investigators who address gaps in the translation of evidence-based cancer prevention and control treatments and interventions into practice.