Caring for Bebe: Early Childhood Obesity Prevention Intervention for Hispanic Families

关爱贝贝：西班牙裔家庭的儿童早期肥胖预防干预

• 批准号: 10673954
• 负责人: Cynthia Nicole Lebron
• 金额: $ 15.55万
• 依托单位: UNIVERSITY OF MIAMI CORAL GABLES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10673954
• 关键词: 5 year old; Acculturation; Address; Adult; Affect; Age; Asian population; Attitude; Award; Behavior; Behavioral; Birth; Black Populations; Black race; Breast Feeding; Cardiovascular Diseases; Caring; Child; Childhood; Chronic Disease; Clinic; Clinical Research; Clip; Communication; Data; Daughter; Development; Diabetes Mellitus; Discipline of obstetrics; Disease; Education; Educational Intervention; Family; Family member; Feasibility Studies; Feedback; Female; Focus Groups; Food; Funding; Generations; Goals; Growth; Health; Health Care Costs; Health Promotion; Health behavior; Heart Diseases; Hematological Disease; High Prevalence; Hispanic; Hispanic Populations; Individual; Infant; Infant Care; Internet; Intervention; Intervention Trial; Knowledge; Latino Population; Length; Life; Link; Literature; Longevity; Lung diseases; Maternal and Child Health; Measures; Mediator; Medical; Methods; Minority; Mission; Modality; Modeling; Mothers; National Heart, Lung, and Blood Institute; Needs Assessment; Non-Insulin-Dependent Diabetes Mellitus; Not Hispanic or Latino; Nursery Schools; Obesity; Outcome; Overweight; Parents; Pregnancy; Pregnant Women; Prevalence; Primary Care; Process; Public Health; Randomized; Recommendation; Recording of previous events; Reporting; Research; Risk; Risk Factors; Sampling; School-Age Population; Science; Self Efficacy; Sleep; Sleep Disorders; Social Network; Social support; Solid; Source; Testing; United States; Weight; Woman; Work; acceptability and feasibility; behavior test; bilingualism; clinical care; comorbidity; design; early childhood; efficacy trial; ethnic disparity; feasibility testing; feasibility trial; feeding; health data; high risk; implementation research; improved; infancy; infant adiposity; minority health; novel diagnostics; novel therapeutic intervention; obesity in children; obesity prevention; obesity risk; pilot test; pregnant; prenatal; prevent; preventive intervention; programs; protective factors; prototype; racial disparity; recruit; research and development; secondary outcome; sleep quality; social cognitive theory; social media; sociodemographics; therapy development; treatment as usual; usability

PROJECT SUMMARY Children who are overweight during early childhood are at least 5 times more likely than normal weight children to be overweight/obese as adults. Yet, for 2 to 5-year-olds, the obesity prevalence is 16.7% for Hispanic children, 12.4% for non-Hispanic Black (NHB) children, 9.3% for non-Hispanic white (NHW) children, and 9.1% for Asians. Once established, obesity and its comorbid medical conditions, many of which disproportionally affect Hispanics, are difficult to treat and usually persist throughout adulthood. Thus, preventing its development as early as possible in life is critical to reduce the health care costs associated with obesity-related chronic diseases such as type 2 diabetes and cardiovascular disease. Hispanic children have a higher prevalence of behaviors and determinants that put them at a high risk of obesity including suboptimal breastfeeding, early introduction of solid foods, and poor infant sleep quality and duration. Current evidence suggests that successful obesity prevention interventions occur in infancy/early childhood and are family- based. However, few studies meet that criteria and even fewer studies target at-risk minorities. The goal of this application is to develop and pilot the feasibility of a social media-based, bilingual, multigenerational entertainment education (EE) intervention for primiparous Hispanic pregnant women and their mothers to prevent the onset of obesity in infants. The aims of this study are to conduct formative research for the development and pilot testing of an early childhood obesity preventive intervention for Hispanic pregnant women and their mothers to establish healthy infant weight, increase breastfeeding, infant sleep, and delay solid food introduction. In Aim 1a, qualitative data will be gathered on mother/grandmother dyads attitudes towards content and user engagement. The results will inform the development of EE video clips and accompanying activities. In Aim1b, we will examine mother/grandmother dyads’ acceptability of developed EE video clips, feasibility of activities, and overall approach to dissemination. A sample of 50 Hispanic pregnant mother-grandmother will be randomly assigned to either the experimental or control condition and followed for 6 months, with assessment at baseline (birth), 3- and 6-months. The control condition will proceed with care as usual. This iterative process will culminate in a pilot test randomizing 50 Hispanic mother-grandmother in a 12 week intervention versus care as usual. Additionally, changes in mother and grandmother health will be assessed as secondary outcomes and changes in social support will be examined as a potential mediators of the effect of condition on outcomes. Covariates include sociodemographic information, health history, measures on breastfeeding self-efficacy, and acculturation. In addition to feasibility and acceptability measures, preliminary effect estimates will be calculated to inform a subsequent R01 trial. This proposed study would help advance science of early childhood obesity prevention interventions by harnessing the power of social media and EE to promote health behaviors among Hispanic families.

在儿童早期超重的儿童， 比正常体重的儿童成年后超重/肥胖。然而，对于2至5岁的儿童， 西班牙裔儿童为16.7%，非西班牙裔黑人儿童为12.4%，非西班牙裔白色儿童为9.3%。 (NHW)9.1%为亚洲人。一旦确定，肥胖及其共病的医疗条件，许多 这些疾病影响西班牙裔人，很难治疗，并且通常持续整个成年期。因此，在本发明中， 在生命中尽早预防其发展对于减少与疾病相关的医疗保健费用至关重要。 肥胖相关的慢性疾病，如2型糖尿病和心血管疾病。西班牙裔儿童有一个 使他们处于肥胖高风险的行为和决定因素的流行率较高，包括次优 母乳喂养、过早摄入固体食物以及婴儿睡眠质量差和持续时间短。目前的证据 表明，成功的肥胖预防干预发生在婴儿期/幼儿期，是家庭- 基于.然而，很少有研究符合这一标准，针对高危少数群体的研究就更少了。这个目标 应用是开发和试点的可行性，社会媒体为基础的，双语，多代 娱乐教育（EE）的干预，为产妇西班牙裔孕妇和他们的母亲， 预防婴儿肥胖症的发生。本研究的目的是进行形成性研究， 西班牙裔孕妇早期儿童肥胖预防干预的开发和试点测试 妇女及其母亲建立健康的婴儿体重，增加母乳喂养，婴儿睡眠，并推迟 固体食物介绍在目标1a中，将收集关于母亲/祖母对态度的定性数据 内容和用户参与度。结果将告知EE视频剪辑的开发， 伴随活动。在Aim 1b中，我们将检查母亲/祖母对发达EE的可接受性 视频剪辑、活动的可行性和传播的总体方法。50名西班牙裔孕妇的样本 母亲-祖母将被随机分配到实验或对照条件下，并随访 6个月，在基线（出生）、3个月和6个月时进行评估。控制条件将谨慎进行， 往常这个反复的过程将最终在一个试点测试随机50西班牙裔母亲，祖母在12个 周干预与常规护理。此外，母亲和祖母健康状况的变化将是 评估为次要结果，社会支持的变化将作为潜在的中介进行检查， 条件对结果的影响。协变量包括社会人口统计学信息、健康史、 母乳喂养自我效能和文化适应措施。除了可行性和可接受性 在采取措施后，将计算初步效应估计值，以便为后续R 01试验提供信息。这项拟议的研究 将有助于促进儿童早期肥胖预防干预的科学， 社交媒体和EE促进西班牙裔家庭的健康行为。