San Diego Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Program

圣地亚哥领导推动代表性不足的神经科学家变革（LAUNCH）计划

• 批准号: 10674057
• 负责人: VIVIAN REZNIK
• 金额: $ 26.13万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674057
• 关键词: Academic skills; Acceleration; Adult; Advanced Development; Affect; African American; Alzheimer' s disease related dementia; American; Area; Award; Biomedical Research; California; Career Mobility; Categories; Censuses; Child; Client satisfaction; Clinical Research; Collaborations; Communication; Development; Diagnosis; Disabled Persons; Disease; Disparity; Diverse Workforce; Doctor of Philosophy; Ethnic Origin; Extramural Activities; Faculty; Fellowship Program; Fostering; Funding; General Population; Goals; Grant; Hispanic Populations; Home; Immersion; Individual; Institution; K-Series Research Career Programs; Knowledge; Mentors; Mentorship; Minority Groups; Minority Women; Modeling; Molecular; National Institute of Neurological Disorders and Stroke; Neurosciences; Neurosciences Research; Participant; Patients; Physicians; Population; Postdoctoral Fellow; Prevalence; Professional Competence; Program Development; Publications; Race; Recording of previous events; Reduce health disparities; Research; Research Personnel; Research Project Grants; Research Training; Scholars Program; Scientist; Self Efficacy; Stroke; Structure; System; Training; Training Programs; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Universities; Woman; Writing; base; black men; career; career development; cohort; disability; ethnic minority; ethnic minority population; evidence base; experience; faculty research; graduate student; improved; medical schools; member; men; minority trainee; nervous system disorder; post-doctoral training; programs; racial minority; racial minority population; recruit; research and development; skill acquisition; skills; stroke therapy; success; tenure track; visiting scholar

The overall goal of the NINDS-proposed UC San Diego Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) program is to effectively mentor and train individuals underrepresented in neurosciences in critical career development skills and research to enhance the development of competitive neuroscience research programs and success in obtaining independent extramural research funding in a visiting scholars program. LAUNCH will utilize asset models and evidence-based strategies to enhance effective mentoring, career skill development, and research training. LAUNCH is directed by five PIs with a history of mentoring and training junior faculty and postdoctoral fellows and success in creating and implementing career development and mentoring programs specifically for underrepresented minority (URM) trainees and women. All PIs have successfully led extramurally funded training programs; four of the five PIs are actively engaged in NIH-sponsored biomedical research, 3 PIs are women, and two PIs are from URM backgrounds. The overall goal of the NINDS-proposed UC San Diego Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) program is to effectively mentor and train underrepresented early career neuroscientists in critical career development and research skills to enhance the development of research programs and success and in obtaining independent extramural research funding. The specific objectives of the UCSD LAUNCH program are to increase the representation of scientists from backgrounds underrepresented in neurosciences in obtaining effective mentorship, critical career development skills, research training and grant funding. Three specific aims are proposed. Aim 1 is to recruit underrepresented junior faculty and transitioning postdoctoral fellows who have neuroscience scientific expertise aligned with those of our research mentors in the areas of Alzheimer's disease and related dementias, cellular, developmental and molecular neurosciences and computational and systems neurosciences, particular strengths of UC San Diego. Aim 2 is to use asset models and evidence-based strategies to enhance career skill development and effective mentorship of participants using a Faculty Research and Career Advancement Plan to identify short- and long-term career and research goals, engage in effective mentorship with a 3-membered mentoring team, and extend knowledge and skills in specific career development areas. Aim 3 is to promote research training and research self-efficacy of participants by extending research knowledge, skills and strategies through direct training with a UCSD faculty research mentor and immersion in activities that will enhance research progress, collaborations and networking, grant writing skills, and as well as publication strategies that will accelerate successful research program development and submission of an NIH or equivalent grant. LAUNCH includes PIs with extensive experience in program and career development and neuroscience research, a strong cohort of UC San Diego faculty neuroscience researchers and career mentors from underrepresented backgrounds.

NINDS提议的加州大学圣地亚哥分校领导代表性不足的神经科学家促进变革（LAUNCH）计划的总体目标是有效地指导和培训神经科学中代表性不足的个人，以提高关键的职业发展技能和研究，以加强竞争性神经科学研究计划的发展，并成功获得独立的校外研究资金访问学者计划。启动方案将利用资产模型和循证战略，加强有效的辅导、职业技能发展和研究培训。LAUNCH由五名PI指导，他们有指导和培训初级教师和博士后研究员的历史，并成功地为代表性不足的少数民族（URM）学员和妇女创建和实施职业发展和指导计划。所有的PI都成功地领导了校外资助的培训计划;五个PI中有四个积极参与NIH赞助的生物医学研究，三个PI是女性，两个PI来自URM背景。NINDS提议的加州大学圣地亚哥分校领导代表性不足的神经科学家促进变革（LAUNCH）计划的总体目标是有效地指导和培训代表性不足的早期职业神经科学家的关键职业发展和研究技能，以加强研究计划的发展和成功，并获得独立的校外研究资金。UCSD LAUNCH计划的具体目标是增加来自神经科学背景的科学家在获得有效指导，关键职业发展技能，研究培训和赠款资金方面的代表性。提出了三个具体目标。目标1是招募代表性不足的初级教师和过渡博士后研究员，他们具有与我们的研究导师在阿尔茨海默病和相关痴呆症，细胞，发育和分子神经科学以及计算和系统神经科学领域的神经科学科学专业知识，特别是UC San Diego的优势。目标2是使用资产模型和循证战略，以提高职业技能发展和有效的指导参与者使用教师研究和职业发展计划，以确定短期和长期的职业和研究目标，从事有效的指导与3元指导团队，并扩展知识和技能在特定的职业发展领域。目标3是通过与加州大学圣地亚哥分校教师研究导师的直接培训和沉浸在能够增强研究进展、合作和网络、资助写作技能的活动中，扩展研究知识、技能和策略，促进参与者的研究培训和研究自我效能。以及将加速成功研究项目开发和提交NIH或同等资助的出版策略。LAUNCH包括在计划和职业发展以及神经科学研究方面拥有丰富经验的PI，一群来自代表性不足背景的UC San Diego教师神经科学研究人员和职业导师。

项目成果

Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model.

• DOI: 10.1038/s41467-022-34679-7
• 发表时间: 2022-11-23
• 期刊: NATURE COMMUNICATIONS
• 影响因子: 16.6
• 作者: Lorden, Gema;Wozniak, Jacob M.;Dore, Kim;Dozier, Lara E.;Cates-Gatto, Chelsea;Patrick, Gentry N.;Gonzalez, David J.;Roberts, Amanda J.;Tanzi, Rudolph E.;Newton, Alexandra C.
• 通讯作者: Newton, Alexandra C.

Sex differences in Alzheimer's disease: do differences in tau explain the verbal memory gap?

• DOI: 10.1016/j.neurobiolaging.2021.05.013
• 发表时间: 2021-11
• 期刊: Neurobiology of aging
• 影响因子: 4.2
• 作者: Banks SJ;Andrews MJ;Digma L;Madsen J;Reas ET;Caldwell JZK;McEvoy LK;Fan CC;Dale AM;Brewer JB;Alzheimer's Disease Neuroimaging Initiative
• 通讯作者: Alzheimer's Disease Neuroimaging Initiative

Elucidating factors contributing to disparities in pain-related experiences among adults with or at risk for knee osteoarthritis.

• DOI: 10.3389/fpain.2023.1058476
• 发表时间: 2023
• 期刊: Frontiers in pain research (Lausanne, Switzerland)

Pain catastrophizing: A patient-centered approach to assessment.

• DOI: 10.1097/01.nurse.0000823252.50782.45
• 发表时间: 2022-04-01
• 期刊: Nursing

Care utilization in eating disorders: for whom are multiple episodes of care more likely?

• DOI: 10.1007/s40519-022-01491-7
• 发表时间: 2022-12
• 期刊: EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
• 影响因子: 2.9
• 作者: Gorrell, Sasha;Le Grange, Daniel;Blalock, Dan, V;Hutchinson, Valerie;Johnson, Madelyn;Duffy, Alan;Mehler, Philip S.;Johnson, Craig;Manwaring, Jamie;McClanahan, Susan;Rienecke, Renee D.
• 通讯作者: Rienecke, Renee D.