NEI UCI Center Core Grant for Vision Research

NEI UCI 中心视觉研究核心资助

基本信息

项目摘要

ABSTRACT This P30 application seeks support for the Cores of Vision Research within the University of California Irvine (UCI) that will strengthen and enhance NEI R01-funded research. The project also aims to support the major expansion of vision research currently under way at UCI. It will broaden and optimize research capabilities, support and expand existing research projects, and help establish new studies, ultimately boosting productivity and strengthening vision research at UCI. Three research Core modules have been identified that would provide substantial benefit to current and future NEI R01-funded projects at UCI: (i). Ocular Microanatomy; (ii) Visual Function and Non-invasive Ocular Imaging; and (iii) Ocular Mass Spectrometry, Lipidomics, and Proteomics. In addition, an Administrative Group will be established to facilitate and support the function of these research Cores. The three research Cores were selected by majority votes of all current NEI R01-funded investigators, and other investigators who are directly or indirectly involved in ophthalmic research at UCI. The most requested services were developed into the Cores described in this P30 application. The vision research community at UCI has grown significantly over the past several years with the recruitment of 4 senior and 2 junior investigators and the formation of the Center for Translational Vision Research (CTVR), with at least two more mid-career faculty recruitments in the works. This expansion has been made possible by the exceptional institutional support from the Department of Ophthalmology and the School of Medicine, who have committed significant financial and infrastructure resources to bolster the vision research community at UCI. The services provided by the Cores for Vision Research will meet the scientific needs of the NEI R01-funded researchers as well as of early-stage investigators, and will increase efficiency, accelerate progress, and encourage new research directions and scientific collaborations at UCI. The Cores will also provide training and access to state-of-the-art experimental tools for students and postdoctoral scholars and will help prepare them for successful careers in ocular research.
摘要

项目成果

期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A novel quantification method for retinal pigment epithelium phagocytosis using a very-long-chain polyunsaturated fatty acids-based strategy.
一种新型的定量方法,用于使用非常长的链多不饱和脂肪酸的策略,用于视网膜色素上皮细胞增多症。
  • DOI:
    10.3389/fnmol.2023.1279457
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    4.8
  • 作者:
    Gao, Fangyuan;Tom, Emily;Lieffrig, Stephanie A.;Finnemann, Silvia C.;Skowronska-Krawczyk, Dorota
  • 通讯作者:
    Skowronska-Krawczyk, Dorota
Saving eyesight, one gene at a time.
  • DOI:
    10.1016/j.molmed.2023.04.008
  • 发表时间:
    2023-07
  • 期刊:
  • 影响因子:
    13.6
  • 作者:
    Holubowicz, Rafal;Palczewski, Krzysztof
  • 通讯作者:
    Palczewski, Krzysztof
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Vladimir Jivkov Kefalov其他文献

Vladimir Jivkov Kefalov的其他文献

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{{ truncateString('Vladimir Jivkov Kefalov', 18)}}的其他基金

Administrative core
行政核心
  • 批准号:
    10676927
  • 财政年份:
    2022
  • 资助金额:
    $ 62.43万
  • 项目类别:
Core 2. Visual Function and Non-invasive Ocular Imaging Core (VFNOIC)
核心 2. 视觉功能和非侵入性眼部成像核心 (VFNOIC)
  • 批准号:
    10676931
  • 财政年份:
    2022
  • 资助金额:
    $ 62.43万
  • 项目类别:
AMD Mitochondria Modulate Expression of microRNA 135b-5p and 148a-3p in RPE Cybrids: Implications for Age-related Macular Degeneration
AMD 线粒体调节 RPE Cybrids 中 microRNA 135b-5p 和 148a-3p 的表达:对年龄相关性黄斑变性的影响
  • 批准号:
    10597239
  • 财政年份:
    2022
  • 资助金额:
    $ 62.43万
  • 项目类别:
Opsin signaling in mammalian rod photoreceptors
哺乳动物视杆光感受器中的视蛋白信号传导
  • 批准号:
    10475531
  • 财政年份:
    2020
  • 资助金额:
    $ 62.43万
  • 项目类别:
Opsin signaling in mammalian rod photoreceptors
哺乳动物视杆光感受器中的视蛋白信号传导
  • 批准号:
    10624391
  • 财政年份:
    2020
  • 资助金额:
    $ 62.43万
  • 项目类别:
PIGMENT DEPHOSPHORYLATION IN MAMMALIAN ROD AND CONE PHOTORECEPTORS
哺乳动物视杆细胞和视锥细胞光感受器中的色素脱磷酸化
  • 批准号:
    9756392
  • 财政年份:
    2016
  • 资助金额:
    $ 62.43万
  • 项目类别:
FASEB SRC on Biology and Chemistry of Vision
FASEB SRC 视觉生物学和化学
  • 批准号:
    8526007
  • 财政年份:
    2013
  • 资助金额:
    $ 62.43万
  • 项目类别:
CALCIUM AND ADAPTATION IN MAMMALIAN CONE PHOTORECEPTORS
钙与哺乳动物视锥光感受器的适应
  • 批准号:
    7990053
  • 财政年份:
    2009
  • 资助金额:
    $ 62.43万
  • 项目类别:
CALCIUM AND ADAPTATION IN MAMMALIAN CONE PHOTORECEPTORS
钙与哺乳动物视锥光感受器的适应
  • 批准号:
    7638095
  • 财政年份:
    2009
  • 资助金额:
    $ 62.43万
  • 项目类别:
CALCIUM AND ADAPTATION IN MAMMALIAN CONE PHOTORECEPTORS
哺乳动物视锥细胞中的钙和适应
  • 批准号:
    7924088
  • 财政年份:
    2009
  • 资助金额:
    $ 62.43万
  • 项目类别:

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