An Implementation-Effectiveness Study of an Evidence-Based Intervention to Improve Head Impact Safety in Youth Football

改善青少年足球头部碰撞安全的循证干预措施的实施效果研究

• 批准号: 10679431
• 负责人: Madison Evelyn Marks
• 金额: $ 4.77万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-09 至 2025-03-08
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10679431
• 关键词: Active Learning; Age; Award; Biomechanics; Biometry; Brain; Brain Concussion; Brain Diseases; Brain Injuries; Certification; Clinical; Clinical Trials Design; Communities; Custom; Data; Data Collection; Development; Effectiveness; Effectiveness of Interventions; Elements; Enrollment; Environment; Evaluation; Evidence based intervention; Exposure to; Fellowship; Frequencies; Funding; Future; Goals; Injury; Intervention; Lead; Life; Manufactured football; Measures; Mentors; Mentorship; Methods; Minor; Monitor; Musculoskeletal Equilibrium; National Institute of Child Health and Human Development; Nerve Degeneration; Nervous System Physiology; Neurocognition; Neurocognitive; Neurologic Deficit; Neuropsychology; Outcome; Parents; Pathology; Pilot Projects; Positioning Attribute; Prevention strategy; Process; Productivity; Public Health; Research; Research Personnel; Safety; Scientist; Seasons; Severities; Sports; Sports Medicine; Structure; Testing; Time; Training; Traumatic Brain Injury; Work; Youth; acceptability and feasibility; clinical outcome assessment; clinical outcome measures; cognitive change; college; comparative; contact sports; data management; effectiveness evaluation; effectiveness/implementation study; experience; head impact; high school; human subject; implementation process; implementation science; implementation strategy; improved; inferential statistics; injury prevention; insight; instrument; intervention program; junior high school; meetings; motor symptom; neurocognitive test; novel; oculomotor; pre-doctoral; prevent; rate of change; recruit; sensor; skills; success; youth sports

PROJECT SUMMARY Repetitive head impacts in contact sports are a significant public health concern due to their potential association with short- and long-term neurological deficits. There is debate amongst researchers as to the amount of exposure that may lead to neurocognitive changes; some researchers have demonstrated that these alterations could occur over the span of one season. Youth football players represent 70% of all athletes participating in the sport and experience over half of their head impacts during practice - an environment amendable to intervention. A current study (1K25HD101686-01A1) will develop an evidence-based intervention aimed to reduce head impact exposure in practices, using a community-engaged approach. This proposal enhances this parent study by incorporating clinical outcome assessments and engaging football athletes in the evaluation of the intervention program. The objective of this implementation-effectiveness study is to evaluate the effectiveness of the intervention program on reducing exposure in practices and its effect on mitigating changes in clinical outcomes, while monitoring the implementation process. In Aim 1, measures of neurocognition, postural control, and vestibular/ocular motor symptoms will be evaluated from athletes participating on control and intervention youth football teams as well as non-contact sports teams at pre- and post-season time points. Biomechanical data informing the frequency and severity of hits during the season will be measured using a custom instrumented mouthpiece. The effectiveness of the intervention at reducing head impact exposure and mitigating changes in clinical outcomes will be evaluated. In Aim 2, the feasibility and potential utility of the implementation strategy of the intervention program will be assessed to inform intervention program outcomes. Former youth football players participating at the high school and collegiate level will be engaged to evaluate the feasibility and acceptability of the intervention program. The results of this study will provide important pilot data on the effect of reducing exposure on clinical outcomes, while informing how the intervention program works and providing valuable insight into future large-scale testing of the intervention. The predoctoral Candidate will achieve the study aims through cross-disciplinary mentorship in injury biomechanics, public health, implementation science, neuropsychology, and sports medicine. This fellowship opportunity will also provide robust didactic training and experiential learning in traumatic brain injury, methods of biomechanical data collection and implementation science, biostatistics, clinical trials design, neurocognitive test administration and interpretation, and professional development. The research and training plan of this Predoctoral Fellowship will position the Candidate for success as a productive independent research scientist with a skillset to combine injury biomechanics and public health to assess injury prevention strategies.

项目摘要 接触性运动中的重复头部撞击是一个重要的公共卫生问题，因为它们之间存在潜在的关联 有短期和长期的神经缺陷研究人员之间存在争议， 暴露可能导致神经认知变化;一些研究人员已经证明，这些变化 可能发生在一个季节的跨度。青年足球运动员占所有参加世界杯的运动员的70%。 运动和经验，超过一半的头部撞击在实践中-一个环境，可干预。 目前的一项研究（1 K25 HD 101686 - 01 A1）将开发一种循证干预措施，旨在降低头部 使用社区参与的方法，在实践中暴露影响。本建议加强了这一父研究 通过纳入临床结果评估和让足球运动员参与干预评估， 程序.这项执行效果研究的目的是评估 减少实践中暴露的干预计划及其对缓解临床变化的影响 成果，同时监测执行进程。在目标1中，测量神经认知、姿势 对照组和前庭/眼运动症状将从参加对照组的运动员中进行评价， 在赛季前和赛季后的时间点，干预青年足球队以及非接触性运动队。 生物力学数据通知的频率和严重性的命中在本赛季将测量使用 定制的仪器接口。干预措施在减少头部撞击暴露方面的有效性， 将评价临床结局的缓解变化。在目标2中， 将评估干预方案的实施战略，以了解干预方案的成果。 参加高中和大学一级的前青年足球运动员将参与评估 干预方案的可行性和可接受性。这项研究的结果将提供重要的试点数据 减少暴露对临床结果的影响，同时告知干预计划如何运作， 为未来大规模的干预测试提供了有价值的见解。博士候选人将 通过在损伤生物力学，公共卫生， 执行科学、神经心理学和运动医学。这一奖学金机会还将提供 创伤性脑损伤的强化教学训练和经验学习，生物力学数据方法 收集和实施科学，生物统计学，临床试验设计，神经认知测试管理和 口译和专业发展。该博士前奖学金的研究和培训计划将 将成功的候选人定位为一名富有成效的独立研究科学家，具有联合收割机的技能 伤害生物力学和公共卫生评估伤害预防策略。