Enhancing Blood Donation at Schools and Beyond: An Implementation Science Study

加强学校及其他场所的献血：一项实施科学研究

• 批准号: 10683391
• 负责人: MINA CHRISTINE HOSSEINIPOUR
• 金额: $ 57.91万
• 依托单位: MALAWI BLOOD TRANSFUSION SERVICE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683391
• 关键词: Age; Anemia; Area; Behavioral Sciences; Blood; Blood Banks; Blood Donations; Blood Transfusion; Cessation of life; Characteristics; Clinical Trials; Collection; Communication; Communities; Consolidated Framework for Implementation Research; Country; Data; Data Reporting; Databases; Discipline of obstetrics; Eligibility Determination; Ensure; Epidemiologic Monitoring; Epidemiology; Evaluation; Event; Familiarity; Focus Groups; Geographic Locations; Geography; Gifts; Goals; Grant; HIV; Health; Hemorrhage; High School Student; Hospitals; Hotlines; Hybrids; Implementation readiness; Infant; Infection; Interdisciplinary Study; Intervention; Interview; Malaria; Malawi; Maternal Mortality; Measures; Mission; Modeling; Modification; Monitor; Motivation; Performance; Phase; Policies; Qualitative Evaluations; Qualitative Methods; Qualitative Research; Randomized; Research; Research Personnel; Risk; Role; Schools; Secondary Schools; Services; Site; Students; System; Telephone; Text Messaging; Time; Transfusion; Update; Vascular blood supply; Youth; community engagement; cost effectiveness; data quality; design; effectiveness evaluation; effectiveness outcome; expectation; experimental study; health data; implementation science; implementation strategy; improved; incentive program; information gathering; meetings; mortality; preference; prevent; preventable death; programs; randomized, clinical trials; recruit; research study; retention rate; service programs; social media; transfusion medicine; transmission process; trial design; uptake; volunteer

Enhancing blood Donation at Schools and Beyond: An implementation Science study Project Summary Over the past decade, Malawi has made substantial progress in improving critical health measures including reducing infant, under-5 years mortality, maternal mortality rate, and HIV associated deaths. Despite this progress, preventable deaths from malaria-associated anemia and obstetric hemorrhage still occur due to blood shortage in the country. Over the last 15 years, the Malawi Blood Transfusion Services (MBTS) has dramatically increased its capacity for blood collection and distribution, but the goal of 100% collection by MBTS has not been achieved and there remains a 27% deficit of the nation’s need. Current MBTS program data suggest secondary student donations programs yield the highest uptake of blood donations but many of these student donors are not retained long term, particularly after graduation. As regular donors provide the lowest risk of transmitted transfusion infections, identifying effective strategies for increasing regular donors is critical in ensuring sustainable supply of safe blood. The application’s emphasis is on identifying sustainable and efficient donor recruitment and retention strategies that would increase safe blood donations in Malawi, taking advantage of the apparent enthusiasm of youth to donate blood and their relatively low risk of transmitted transfusion infections. Specifically, three aims will be implemented: Phase 1 (UG3), Aim 1: Conduct spatial, epidemiological and Hemovigilance analysis of existing MBTS and Ministry of Health (MOH) data from current blood collections systems to identify optimal functioning districts for replication, data quality improvement and potential inclusion for implementation science trial; Aim 2: Conduct evaluation of facilitators and barriers to blood collection and repeat donations according to high and low performing districts/programs/schools in order to inform and refine implementation science strategy; and Phase 2 (UH3), Aim 3: Determine the effectiveness of an enhanced Malawian-tailored school-based donation club program to promote first time donation and engage donor retention post-secondary school. Informed by a Consolidated Framework for Implementation Research, we expect this proposed trial will yield culturally sensitive, age appropriate incentive programs, donor messaging and communication strategies to maximize enthusiasm for donation. The consortium brings together a multi-disciplinary research team with expertise in blood transfusion medicine, epidemiology, behavioral science, implementation science and familiarity with the Malawian culture and context to achieve the objectives. Implementation science capacity building for young Malawian investigators is embedded within the grant’s activities to ensure continued research in blood transfusion medicine long term.

加强学校及其他地区的献血：一项实施科学研究 项目摘要 在过去十年中，马拉维在改善关键健康方面取得了重大进展， 采取措施，包括降低婴儿、5岁以下儿童死亡率、孕产妇死亡率和艾滋病毒 相关死亡。尽管取得了这一进展， 由于血液短缺，产科出血仍时有发生。在过去的15年里， 马拉维输血服务中心（MBTS）大大提高了血液供应能力， 收集和分发，但MBTS 100%收集的目标尚未实现， 仍有27%的赤字。目前的MBTS项目数据表明， 学生捐赠计划产生的献血率最高，但许多这些学生 捐助者不能长期留用，特别是在毕业后。由于经常捐助者提供 输血传播感染的风险最低，确定有效的策略， 定期献血对确保安全血液的可持续供应至关重要。 该应用程序的重点是确定可持续和有效的捐助者征聘， 保留战略，这将增加马拉维的安全献血，利用 青年献血热情明显， 输血感染具体而言，将实现三个目标：第1阶段（UG 3），目标1： 对现有MBTS和卫生部进行空间、流行病学和血液警戒分析 卫生部（MOH）从目前的血液采集系统的数据，以确定最佳的功能 复制、数据质量改进和可能纳入执行工作的地区 科学试验;目标2：对采血的促进因素和障碍进行评价， 根据表现优异和较差的地区/项目/学校重复捐款，以便 第二阶段（UH 3），目标3： 增强马拉维量身定制的学校捐赠俱乐部计划的有效性， 促进首次捐赠，并让捐赠者留在中学后学校。依托简明扼要 实施研究的综合框架，我们预计这项拟议的试验将产生 具有文化敏感性、适合年龄的激励计划、捐助者信息传递和沟通 最大限度地提高捐赠热情的策略。 该联盟汇集了一支具有血液专业知识的多学科研究团队 输血医学、流行病学、行为科学、实施科学和熟悉 马拉维的文化和背景，以实现这些目标。执行科学能力 为年轻的马拉维调查人员建立的建筑是赠款活动的一部分，以确保 长期从事输血医学研究。