Developmental and Mentoring Core

摘要：企业核心 UNC-Malawi-South Africa Cancer Consortium（USSACC）致力于培养下一代癌症患者。 从业者和领导者进行高影响力的研究艾滋病毒相关的恶性肿瘤在低和中等， 收入国家（LMIC）的设置。我们建议的发展和指导核心（发展核心）将 嵌入现有的，非常成功的，NIH支持的研究培训基础设施， 在过去的二十年里，与马拉维和南非的LMIC合作伙伴建立了合作关系。尽管我们的许多 培训的成功，调查人员在LMIC设置的一个中心问题是缺乏专门的职业生涯 发展支持和保护的时间进行研究和争取独立的资金。我们 建议通过对职业生涯早期的培训和辅导采取综合办法来解决这一问题 癌症研究者首先，我们将创建一个强大的导师计划，以支持至少 九名非洲和美国的调查员导师制将侧重于设计和实施假设驱动的 研究，手稿写作和赠款的发展。第二，我们将发挥持续的领导作用， 马拉维和南非的发展计划，以培养强大的研究主管/导师库 为医疗和公共卫生受训人员提供培训。第三，我们将提供至少15项研究赠款， 非洲和美国调查人员支持假设驱动的研究项目和/或获取初步数据 与艾滋病毒相关的恶性肿瘤相关的较大赠款申请。

ABSTRACT: DEVELOPMENTAL CORE The UNC-Malawi-South Africa Cancer Consortium (UMSACC) seeks to train the next generation of practitioners and leaders to conduct high-impact research on HIV-Associated malignancies in low- and middle- income country (LMIC) settings. Our proposed Developmental and Mentoring Core (Developmental Core) will be embedded within the existing, highly successful, NIH-supported research training infrastructure that UNC has established with LMIC partners in Malawi and South Africa over the past two decades. Despite our many training successes, a central problem for investigators in LMIC settings is the lack of dedicated career development support and protected time to conduct research and compete for independent funding. We propose to address this problem through a comprehensive approach to training and mentoring early-career cancer researchers. First, we will create a strong mentorship program to support the development of at least nine African and U.S. investigators. Mentorship will focus on design and implementation of hypothesis-driven research, manuscript writing, and development of grants. Second, we will leverage ongoing leadership development programs in Malawi and South Africa to develop a strong pool of research supervisors/mentors for medical and public health trainees. Third, we will provide at least 15 mentored research grants to promising African and U.S. investigators to support hypothesis-driven research projects and/or obtain preliminary data for larger grant applications related to HIV-associated malignancies.