Administrative Core: Biomolecular Structure and Dynamics

行政核心：生物分子结构和动力学

• 批准号: 10684913
• 负责人: BRUCE E BOWLER
• 金额: $ 23.95万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-10 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10684913
• 关键词: Advisory Committees; Applications Grants; Area; Award; Biomedical Research; Budgets; Centers of Research Excellence; Charge; Collaborations; Communication; Communities; Core Facility; Counseling; Coupled; Data; Educational workshop; Ensure; Environment; Evaluation; Evolution; Feedback; Funding; Future; Goals; Grant; Grant Review; Growth; Income; Leadership; Mentors; Mission; Molecular; Monitor; Montana; Occupational activity of managing finances; Phase; Pilot Projects; Progress Reports; Regulation; Research; Research Personnel; Resources; Role; Science; Series; Services; Structural Biologist; Structure; United States National Institutes of Health; Universities; Water; Writing; base; career; improved; informal atmosphere; instrumentation; meetings; member; operation; outreach; peer; programs; recruit; success; synergism; voucher

The defining role of the Administrative (Admin) Core of the Center for Biomolecular Structure and Dynamics (CBSD) during phase III COBRE funding is to provide the framework that guides efficient and strategic operation of the CBSD so that it becomes a self-sustaining research center at the University of Montana (UM). This task will be led by PD Bruce E. Bowler with assistance from Assistant Director for Budget and Finance Heidi Boggs and her staff. The focus of phase III funding will be on affording guidance and resources to the four research cores supported by the CBSD so that they can grow their user bases and maintain state-of-the- art facilities that will be necessary to give their users a competitive edge for research funding. The Admin Core will build upon the successful programs administered during phases I and II of COBRE funding, which led to 58 grant awards to CBSD investigators that brought in more than $27 million in funding to support their research and use of the four research cores that are critical for maintaining their research programs at the forefront of their research areas. During phase III, the goal of achieving long term sustainability for the CBSD will be achieved by optimizing core recharge structures (specific aim 2) and promoting further growth of research core user bases by 1) ensuring that they continue to offer state-of-the-art facilities (specific aim 1), 2) by facilitating strategic use of Pilot Project grants and 3) by partnering with other COBRE centers at UM and in nearby IDeA states with overlapping needs (specific aim 2). Closely coupled to these core-centric strategies are mentoring programs that keep the research of CBSD researchers at the vanguard of their science (specific aim 3). These programs include 1) the Hot Water grant writing workshop that provides panel-style review of grants before submission that help CBSD researchers at all career stages improve both the clarity and quality of their grant applications and 2) the monthly CBSD Research Meeting that provides a forum for CBSD investigators to present their research in an informal environment meant to stimulate new ideas and promote collaboration with their peers. The Admin Core will also focus the weekly Molecular and Biomedical Sciences Seminar series on prominent outside speakers whose research highlights the leading edge science made possible by our research cores (specific aim 4). This integrated approach will create synergies between the cutting-edge capabilities of our research cores and a scientifically stimulating environment that will grow the research enterprise of the CBSD ensuring its long-term sustainability. Oversight and guidance for this evolution will be provided by our Internal Advisory Committee, which includes representative members of the CBSD community, and an External Advisory Committee comprised of eminent biophysicists and structural biologists.

生物分子结构与动力学中心行政（Admin）核心的决定性作用 (CBSD) 在第三阶段 COBRE 资助期间，旨在提供指导高效和战略性框架 CBSD 的运营，使其成为蒙大拿大学 (UM) 的一个自我维持的研究中心。 这项任务将由 PD Bruce E. Bowler 领导，并由预算和财务助理总监协助 海蒂·博格斯和她的员工。第三阶段资金的重点将是为 CBSD 支持的四个研究核心，以便他们能够扩大用户群并保持最新状态 为用户提供研究经费竞争优势所必需的艺术设施。管理核心 将建立在 COBRE 资助第一阶段和第二阶段管理的成功计划的基础上，这些计划导致 58 向 CBSD 研究人员提供资助，为他们的研究带来了超过 2700 万美元的资金支持 并利用四个研究核心，这对于保持其研究项目处于前沿至关重要 他们的研究领域。在第三阶段，实现 CBSD 长期可持续性的目标将是 通过优化核心补给结构（具体目标2）和促进研究的进一步发展来实现 核心用户群： 1) 确保他们继续提供最先进的设施（具体目标 1), 2) 促进试点项目赠款的战略使用，以及 3) 与 UM 和其他州的其他 COBRE 中心合作 附近具有重叠需求的 IDeA 州（具体目标 2）。与这些以核心为中心的战略紧密结合 正在开展指导计划，使 CBSD 研究人员的研究始终处于科学前沿 （具体目标3）。这些计划包括 1) 热水拨款写作研讨会，提供小组式的 在提交之前对资助进行审查，帮助 CBSD 研究人员在各个职业阶段提高清晰度 以及他们的资助申请的质量和 2) 每月一次的 CBSD 研究会议，为 CBSD 研究人员在非正式的环境中展示他们的研究，旨在激发新的想法和 促进与同行的合作。管理核心还将关注每周的分子和生物医学 科学研讨会系列，由杰出的外部演讲者组成，其研究突出了前沿科学 我们的研究核心使之成为可能（具体目标 4）。这种综合方法将在以下方面产生协同效应： 我们的研究核心的尖端能力和科学刺激的环境将发展 CBSD 的研究企业确保其长期可持续性。对这一演变的监督和指导 将由我们的内部咨询委员会提供，其中包括 CBSD 的代表成员 社区，以及由著名生物物理学家和结构生物学家组成的外部咨询委员会。