Administrative Core: Biomolecular Structure and Dynamics

行政核心：生物分子结构和动力学

• 批准号: 10684913
• 负责人: BRUCE E BOWLER
• 金额: $ 23.95万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-10 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10684913
• 关键词: Advisory Committees; Applications Grants; Area; Award; Biomedical Research; Budgets; Centers of Research Excellence; Charge; Collaborations; Communication; Communities; Core Facility; Counseling; Coupled; Data; Educational workshop; Ensure; Environment; Evaluation; Evolution; Feedback; Funding; Future; Goals; Grant; Grant Review; Growth; Income; Leadership; Mentors; Mission; Molecular; Monitor; Montana; Occupational activity of managing finances; Phase; Pilot Projects; Progress Reports; Regulation; Research; Research Personnel; Resources; Role; Science; Series; Services; Structural Biologist; Structure; United States National Institutes of Health; Universities; Water; Writing; base; career; improved; informal atmosphere; instrumentation; meetings; member; operation; outreach; peer; programs; recruit; success; synergism; voucher

The defining role of the Administrative (Admin) Core of the Center for Biomolecular Structure and Dynamics (CBSD) during phase III COBRE funding is to provide the framework that guides efficient and strategic operation of the CBSD so that it becomes a self-sustaining research center at the University of Montana (UM). This task will be led by PD Bruce E. Bowler with assistance from Assistant Director for Budget and Finance Heidi Boggs and her staff. The focus of phase III funding will be on affording guidance and resources to the four research cores supported by the CBSD so that they can grow their user bases and maintain state-of-the- art facilities that will be necessary to give their users a competitive edge for research funding. The Admin Core will build upon the successful programs administered during phases I and II of COBRE funding, which led to 58 grant awards to CBSD investigators that brought in more than $27 million in funding to support their research and use of the four research cores that are critical for maintaining their research programs at the forefront of their research areas. During phase III, the goal of achieving long term sustainability for the CBSD will be achieved by optimizing core recharge structures (specific aim 2) and promoting further growth of research core user bases by 1) ensuring that they continue to offer state-of-the-art facilities (specific aim 1), 2) by facilitating strategic use of Pilot Project grants and 3) by partnering with other COBRE centers at UM and in nearby IDeA states with overlapping needs (specific aim 2). Closely coupled to these core-centric strategies are mentoring programs that keep the research of CBSD researchers at the vanguard of their science (specific aim 3). These programs include 1) the Hot Water grant writing workshop that provides panel-style review of grants before submission that help CBSD researchers at all career stages improve both the clarity and quality of their grant applications and 2) the monthly CBSD Research Meeting that provides a forum for CBSD investigators to present their research in an informal environment meant to stimulate new ideas and promote collaboration with their peers. The Admin Core will also focus the weekly Molecular and Biomedical Sciences Seminar series on prominent outside speakers whose research highlights the leading edge science made possible by our research cores (specific aim 4). This integrated approach will create synergies between the cutting-edge capabilities of our research cores and a scientifically stimulating environment that will grow the research enterprise of the CBSD ensuring its long-term sustainability. Oversight and guidance for this evolution will be provided by our Internal Advisory Committee, which includes representative members of the CBSD community, and an External Advisory Committee comprised of eminent biophysicists and structural biologists.

生物分子结构和动力学中心行政核心的定义作用 在COBRE第三阶段期间，CBSD（CBSD）的资助是提供指导有效和战略性的框架， CBSD的运作，使其成为蒙大拿大学（UM）的自我维持的研究中心。 该任务将由PD布鲁斯E领导。鲍勒在预算和财务助理主任的协助下 海蒂·博格斯和她的员工第三阶段供资的重点将是为下列机构提供指导和资源： CBSD支持的四个研究核心，以便他们能够扩大用户群并保持最佳状态。 艺术设施，这将是必要的，让他们的用户在研究资金的竞争优势。管理核心 将在COBRE资助第一和第二阶段管理的成功项目的基础上再接再厉，该阶段已完成58个项目 向CBSD调查人员提供奖励，为他们的研究带来了超过2700万美元的资金支持 并使用四个研究核心，这对于保持他们的研究计划处于最前沿至关重要， 他们的研究领域。在第三阶段，实现CBSD长期可持续性的目标将是 通过优化核心补给结构（具体目标2）和促进研究的进一步发展来实现 核心用户群：1）确保他们继续提供最先进的设施（具体目标1），2） 促进试点项目赠款的战略使用和3）通过与其他COBRE中心在UM和 有重叠需求的附近IDEA州（具体目标2）。与这些以核心为中心的战略紧密结合 是指导计划，保持CBSD研究人员的研究在他们的科学前沿 （具体目标3）。这些方案包括1）热水赠款写作讲习班，提供小组式 在提交之前审查赠款，帮助CBSD研究人员在所有职业阶段提高清晰度， 和质量的补助金申请和2）每月CBSD研究会议，提供了一个论坛， CBSD研究人员在非正式的环境中展示他们的研究，旨在激发新的想法， 促进与同行的合作。管理核心还将关注每周的分子和生物医学 科学研讨会系列突出的外部发言人，其研究突出了前沿科学 通过我们的研究核心（具体目标4）实现。这一综合办法将在以下方面产生协同增效作用： 我们的研究核心的尖端能力和科学刺激的环境，将增长 CBSD的研究企业，确保其长期可持续性。监督和指导这一演变 将由我们的内部咨询委员会提供，其中包括CBSD的代表成员 社区，以及由著名生物学家和结构生物学家组成的外部咨询委员会。