Physiology of bacterial metabolism in the human gut microbiome

人类肠道微生物群中细菌代谢的生理学

• 批准号: 10686712
• 负责人: Dylan Dodd
• 金额: $ 4.8万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-02 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10686712
• 关键词: Administrative Supplement; Animals; Bacterial Physiology; Biochemistry; Biological; Career Choice; Chemistry; Compensation; Development Plans; Funding; Genus Mycobacterium; Goals; Grant; Health; Human; Institution; Laboratories; Latina; Mentorship; Metabolism; Mission; Parents; Pathway interactions; Physiology; Polymers; Postdoctoral Fellow; Research; Research Training; Training; United States National Institutes of Health; Urate Oxidase; Uric Acid; bacterial metabolism; career development; design; experience; gut bacteria; gut microbiome; gut microbiota; parent grant

Summary: This application is for an administrative supplement to enhance diversity in health-related research under the aims of the parent grant, “Physiology of bacterial metabolism in the human gut microbiome” (GM142873). The supplemental funds will provide support for Dr. Michelle Miranda-Velez, a post-doctoral scholar in the PI’s laboratory. Dr. Miranda-Velez has extensive expertise in chemistry, synthesizing polymers with biological activity against Mycobacteria. The current supplement will provide a rigorous research training experience for Dr. Miranda-Velez in the biochemistry and physiology of the human gut microbiota. In addition, it will provide an individualized mentorship and career development plan designed to support Dr. Miranda-Velez as she follows her chosen career path to start her own independent research group at a US academic institution. While advancing the NIH mission for enhancing diversity, the proposed supplement will also enhance the goals of the parent grant.

概括： 本申请是行政补充，旨在增强健康相关研究的多样性 母基金的目标是“人类肠道微生物组细菌代谢的生理学”(GM142873)。这 补充资金将为 PI 的博士后学者 Michelle Miranda-Velez 博士提供支持 实验室。 Miranda-Velez 博士在化学、生物合成聚合物方面拥有丰富的专业知识 对抗分枝杆菌的活性。当前的补充将为以下人员提供严格的研究培训经验 Miranda-Velez 博士研究人类肠道微生物群的生物化学和生理学。此外，还将提供 旨在支持 Miranda-Velez 博士的个性化指导和职业发展计划 遵循她选择的职业道路，在美国学术机构创办了自己的独立研究小组。 在推进 NIH 增强多样性使命的同时，拟议的补充也将增强目标 的父母补助金。

项目成果

Tutorial: Microbiome studies in drug metabolism.

• DOI: 10.1111/cts.13416
• 发表时间: 2022-12
• 期刊: CTS-CLINICAL AND TRANSLATIONAL SCIENCE
• 影响因子: 3.9
• 作者: Dodd, Dylan;Cann, Isaac
• 通讯作者: Cann, Isaac