Administrative Core

项目摘要--核心A 管理核心对无墙路易体痴呆中心(LBD)的运营至关重要 哇)。它提供对所有核心和项目的行政、财政和科学监督。它负责 维护中心科技成果报道网页，建立一个公开的- 由该中心鉴定的α-突触核蛋白和淀粉样β蛋白所有亚种的可用文库。在……里面 与LBD CWow的其他组件相结合，Core A确保教育材料、数据、 研究资源可用于与其他CWOW和非CWOW LBD调查人员共享。 核心A确保LBD CWow将与NINDS计划充分合作，并拥有专门的中心 具有大型跨机构财务和行政管理经验的行政人员 助学金以及在梅奥诊所脑库中导航的专业知识。为了实现这些目标，核心A有 以下具体目标：具体目标1：提供行政结构和财政监督 哇哦。具体目标2：承担中心活动的质量控制责任，确保 负责任地进行研究以及研究实践的严密性和可重复性。具体目标3：促进 通过组织定期执行指导来科学指导和整合中心组件 委员会会议和监督支持中心核心和项目的外部合作。 具体目标4：建立一个外部咨询委员会，并向国家卫生研究院报告进展情况。具体目标5： 建立和维护一个公开可用的所有α-SYN和Aβ亚种文库，该亚种的特征是 LBD CWow网站的形式。具体目标6：推广LBD教育，鼓励CWW 调查人员参加病人和照顾者支持小组。

PROJECT SUMMARY – CORE A The Administrative Core is crucial to the operation of the Lewy body dementia Center without Walls (LBD CWOW). It provides administrative, fiscal, and scientific oversight of all cores and projects. It is responsible for maintaining a webpage for reporting on scientific achievements of the Center and establishing a publicly- available library of all subspecies of alpha-synuclein and amyloid-beta characterized by the Center. In conjunction with the other components of the LBD CWOW, Core A assures that educational materials, data, and research resources are available for sharing with other CWOWs and with non-CWOW LBD investigators. Core A assures that the LBD CWOW will cooperate fully with NINDS initiatives and has a dedicated Center Administrator who has experience with fiscal and administrative management of large multi-institutional grants as well as expertise in navigating the Mayo Clinic Brain Bank. To accomplish these goals, Core A has the following specific aims: Specific Aim 1: Provide administrative structure and fiscal oversight for the CWOW. Specific Aim 2: Assume responsibility for the quality control of the Center’s activities by ensuring responsible conduct of research and rigor and reproducibility of research practices. Specific Aim 3: Promote the scientific direction and integration of the Center components by organizing regular Executive Steering Committee meetings and overseeing external collaborations that support the Center cores and projects. Specific Aim 4: Establish an External Advisory Committee and report progress to the NIH. Specific Aim 5: Establish and maintain a publicly-available library of all α-syn and Aβ subspecies characterized by the center in the form of a LBD CWOW website. Specific Aim 6: Promote education on LBD and encourage CWOW investigators to participate in patient and caregiver support groups.