Multidisciplinary Training Program in Basic Diabetes Research

摘要 糖尿病及其并发症的负担强调了继续培训下一个 一代合格的科学家开发新的想法和新的治疗方法， 预防和治疗糖尿病。这项培训补助金的主要目标是准备博士基本 科学家在糖尿病研究的职业生涯。培训内容包括多学科和全面的 学习经验，以及指导和实验室研究经验， 深入了解糖尿病的分子方面。这个培训项目是嵌入式的 在密歇根大学丰富的研究环境中，包括一个高度学院化的， 跨学科糖尿病研究社区，拥有优秀的核心资源，支持生物医学 research.该培训计划建立在导师的独特专业知识基础上，分为六个主要领域。 兴趣小组-胰岛生物学、自体免疫糖尿病、脂肪细胞生物学、下丘脑调节 代谢、胰岛素抵抗机制和代谢控制（肝脏、脂肪细胞和肌肉 组）和糖尿病并发症。该计划包括培训，发生在个人 研究实验室，但由核心课程补充-与分子讲座 糖尿病的发病机制，细胞和发育生物学，负责任的研究行为， 研究方法。此外，学员还参加各种跨学科研讨会、活动 在赠款写作，职业战略讲习班，并会见来访的发言人。主任指导 学员在个人和小组会议。本培训旨在提供必要的工具， 过渡到独立。该计划包括27名导师在一个高度协作的环境， 都有稳定的校外资助导师在他们的专业领域是多样化的， 在运动学，文学科学与艺术学院，以及许多部门和部门内的 医学院。该计划将为密歇根州的使命提供重要补充 支持研究的糖尿病研究中心和营养与肥胖研究中心 基础设施，但没有为博士后培训人员提供支持。这个训练项目将由 由一个执行委员会组成，该委员会由主要研究者和联席主任以及三名成员组成 他们都是资深调查员，有着良好的指导记录。

Abstract The burden of diabetes and its complications underscores the continued need to train the next generation of well-qualified scientists to develop new ideas and novel therapies for the treatment, prevention and cure of diabetes. The primary goal of this training grant is to prepare PhD basic scientists for careers in diabetes research. The training includes multidisciplinary and comprehensive learning experiences, as well as the mentorship and laboratory research experiences required to develop a deep understanding of the molecular aspects of diabetes. This training program is embedded within the rich research environment of the University of Michigan, which includes a highly collegial, interdisciplinary diabetes research community with outstanding core resources to support biomedical research. The training program builds on the unique expertise of preceptors, which fall into six major interest groups – islet biology, autoimmune diabetes, adipocyte biology, hypothalamic regulation of metabolism, mechanisms of insulin resistance and metabolic control (liver, adipocyte and muscle groups), and diabetes complications. The program includes training that occurs within individual research laboratories, but is supplemented by a core curriculum - with lectures on molecular pathogenesis of diabetes, cell and developmental biology, responsible conduct of research, and research methodologies. In addition, the trainees attend a variety of interdisciplinary seminars, activities in grant writing, career strategy workshops, and meet with visiting speakers. The Director mentors the trainees in individual and small group sessions. This training is designed to provide the necessary tools for transition to independence. This program includes 27 mentors in a highly collaborative environment, all with stable extramural funding. The mentors are diverse in their area of specialty, with appointments in Schools of Kinesiology, Literature Sciences & Arts, and many departments and divisions within the School of Medicine. This program will provide a significant complement for the missions of the Michigan Diabetes Research Center and the Nutrition and Obesity Research Center, which support research infrastructure but provide no support for postdoctoral trainees. This training program will be overseen by an executive committee comprising the Principal Investigator and co-director, plus three members all of whom are senior investigators with strong mentoring track records.