Multidisciplinary Training Program in Basic Diabetes Research

摘要 糖尿病及其并发症的负担强调了继续需要培训下一代 一代合格的科学家为治疗开发新的想法和新的疗法， 糖尿病的防治。这项培训基金的主要目标是准备博士基础 糖尿病研究领域的科学家。培训内容包括多学科和综合性。 学习经验，以及所需的指导和实验室研究经验 对糖尿病的分子方面有深入的了解。该培训计划已嵌入 在密歇根大学丰富的研究环境中，包括一个高度合作的， 跨学科糖尿病研究社区，拥有支持生物医学的杰出核心资源 研究。该培训计划建立在导师独特的专业知识基础上，这些专家分为六大类 兴趣小组-胰岛生物学、自身免疫性糖尿病、脂肪细胞生物学、下丘脑调节 代谢、胰岛素抵抗的机制和代谢控制(肝脏、脂肪细胞和肌肉 组)和糖尿病并发症。该计划包括在个人内部进行的培训 研究实验室，但辅之以核心课程--关于分子的讲座 糖尿病的发病机制，细胞和发育生物学，负责任的研究行为，以及 研究方法。此外，学员还参加了各种跨学科的研讨会、活动 参与赠款撰写、职业战略研讨会，并与来访的演讲者会面。该署署长指导 参加个人和小组会议的受训人员。本培训旨在提供必要的工具 为了过渡到独立。该项目包括27名导师，他们处于高度协作的环境中， 所有这些都有稳定的外部资金。导师在他们的专业领域是不同的，有任命 在运动学、文学科学和艺术学院，以及 医学院。这一计划将为密歇根的使命提供一个重要的补充 支持研究的糖尿病研究中心和营养与肥胖研究中心 基础设施，但不为博士后实习生提供支持。这一培训计划将受到监督 由首席调查员和联席主任组成的执行委员会，以及三名成员 他们都是资深调查人员，有很好的指导记录。

Abstract The burden of diabetes and its complications underscores the continued need to train the next generation of well-qualified scientists to develop new ideas and novel therapies for the treatment, prevention and cure of diabetes. The primary goal of this training grant is to prepare PhD basic scientists for careers in diabetes research. The training includes multidisciplinary and comprehensive learning experiences, as well as the mentorship and laboratory research experiences required to develop a deep understanding of the molecular aspects of diabetes. This training program is embedded within the rich research environment of the University of Michigan, which includes a highly collegial, interdisciplinary diabetes research community with outstanding core resources to support biomedical research. The training program builds on the unique expertise of preceptors, which fall into six major interest groups – islet biology, autoimmune diabetes, adipocyte biology, hypothalamic regulation of metabolism, mechanisms of insulin resistance and metabolic control (liver, adipocyte and muscle groups), and diabetes complications. The program includes training that occurs within individual research laboratories, but is supplemented by a core curriculum - with lectures on molecular pathogenesis of diabetes, cell and developmental biology, responsible conduct of research, and research methodologies. In addition, the trainees attend a variety of interdisciplinary seminars, activities in grant writing, career strategy workshops, and meet with visiting speakers. The Director mentors the trainees in individual and small group sessions. This training is designed to provide the necessary tools for transition to independence. This program includes 27 mentors in a highly collaborative environment, all with stable extramural funding. The mentors are diverse in their area of specialty, with appointments in Schools of Kinesiology, Literature Sciences & Arts, and many departments and divisions within the School of Medicine. This program will provide a significant complement for the missions of the Michigan Diabetes Research Center and the Nutrition and Obesity Research Center, which support research infrastructure but provide no support for postdoctoral trainees. This training program will be overseen by an executive committee comprising the Principal Investigator and co-director, plus three members all of whom are senior investigators with strong mentoring track records.