Enhancing Precision of Estimates of Sexual Orientation and Gender Identity Disparities in Tobacco and Cannabis use in Young People

提高年轻人烟草和大麻使用中性取向和性别认同差异的估计精度

• 批准号: 10831803
• 负责人: Jessica Louise Barrington-Trimis
• 金额: $ 9.6万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-20 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10831803
• 关键词: Address; Administrative Supplement; Adolescent; Adolescent and Young Adult; Adverse effects; Age; Age Months; Anxiety Disorders; Attention deficit hyperactivity disorder; Behavioral; California; Cannabinoids; Cannabis; Characteristics; Chronic; Chronology; Cigarette; Data; Data Analyses; Data Sources; Dependence; Development; Devices; Disease; Disparity; Drug abuse; Drug usage; Emotional; Ethnic Origin; Expectancy; Flavoring; Frequencies; Friends; Funding; Future; Gender; Gender Identity; Goals; Health; High School Student; Impulsivity; Individual; Inequity; Intervention; JUUL; Left; Link; Longitudinal cohort study; Low Prevalence; Malignant Neoplasms; Manuscripts; Marijuana Smoking; Measurement; Measures; Modeling; Mood Disorders; Nicotine; Oils; Outcome; Parents; Participant; Persons; Pharmaceutical Preparations; Plants; Play; Policies; Policy Maker; Population; Preparation; Prevention; Prevention strategy; Problem behavior; Proliferating; Public Health; Race; Research; Research Personnel; Rewards; Risk; Risk Factors; Role; Sampling; Schools; Science; Scientist; Self Administration; Sex Orientation; Sexuality; Students; Surveys; THC concentration; Technology; Testing; Time; Tobacco; Tobacco use; Variant; Vulnerable Populations; Wages; Waxes; Youth; aged; asexual; biopsychosocial; cancer health disparity; catalyst; cohort; combustible tobacco; design; deviant; digital; distress tolerance; electronic cigarette use; experience; experimental study; flexibility; follow-up; habituation; health equity promotion; heated tobacco products; high risk; high school; interest; marijuana use; marijuana vaping; multiple drug use; nicotine exposure; nicotine use; ninth grade; nonbinary; novel; pansexual; parent project; prevent; programs; public health priorities; recruit; response; risk prediction; secondary analysis; sexual identity; sexual minority; social; stem; tobacco products; trait; uptake; vaping; vaping nicotine; young adult

PROJECT SUMMARY FOR ADMINISTRATIVE SUPPLEMENT PROJECT This application is being submitted in response to the Notice of Special Interest (NOSI) identified as “NOT-CA- 23-032. Obtaining estimates of disparities in tobacco product and cannabis use associated with sexual orientation and gender identity (SOGI) among adolescents and young adults (AYAs) is vital for informing strategies to reverse cancer inequities. Existing estimates of SOGI disparities use measures that are insufficiently inclusive, leaving unclear whether disparities extend to specific SOGIs that are often overlooked (e.g., asexual, pansexual, gender non-binary). To address this gap, this administrative supplement will conduct a new secondary analysis of the association of 8 different sexual orientation identities and 5 different gender identities with the use and poly-use of 8 different tobacco and cannabis products. We leverage a NCI-funded R01 parent project (R01-CA0229617) including longitudinal cohort studies of 3,915 adolescents and 2,526 young adults that examines risk factors and consequences of nicotine and cannabis vaping. At each of 5 (semi)annual survey waves conducted 2019-2023, detailed data on tobacco and cannabis product use are being collected for the parent R01’s primary aims, and detailed SOGI data are being collected for descriptive information about the cohorts. This supplement requests funding to cover salary effort for investigators and statisticians to conduct data analysis and manuscript preparation for this new secondary analysis. The primary goal of the supplement project is to determine the concurrent association of various SOGIs with past-30-day tobacco and cannabis product use frequency and poly-use statuses in an adolescent cohort and in a young adult cohort. The secondary goals are to examine whether these associations vary across individuals with changing vs. static SOGIs, chronological time, and race/ethnicity. Because we have repeated measures of SOGI and tobacco/cannabis use, we will have up to 14,843 and 9103 data points for adolescent and young adult cohorts, respectively, which will provide unprecedented power to examine lower prevalence SOGIs (e.g., asexual, pansexual, questioning sexuality, gender non-binary). At the end of this Administrative Supplement project, we will have some of the most contemporary, inclusive, and detailed estimates of SOGI disparities in tobacco and cannabis product use in the vulnerable population of AYAs. This will inform: (a) precise public health measures to reduce SOGI cancer disparities; and (b) if more inclusive measurement of SOGI is needed in national tobacco/cannabis use surveys of AYAs in order to avoid overlooking disparities and, in turn, groups in need of intervention.

行政管理项目的项目摘要 本申请是为了响应被标识为“NOT-CA-”的特别利益通知（NOSI）而提交的。 23-032.获得与性行为有关的烟草制品和大麻使用差异的估计数 青少年和年轻人（AYAs）的取向和性别认同（SOGI）对于提供信息至关重要 扭转癌症不平等的战略。对SOGI差异的现有估计使用的是 包容性不足，不清楚差异是否延伸到经常被忽视的特定SOGI (e.g.,无性恋、泛性恋、性别非二元）。为了弥补这一差距，本行政补充文件将 对8种不同性取向身份和5种不同性别之间的关联进行了新的二次分析 使用和多种使用8种不同的烟草和大麻产品。我们利用国家癌症研究所资助的 R 01母项目（R 01-CA 0229617），包括3,915例青少年和2,526例年轻人的纵向队列研究 成人检查尼古丁和大麻vaping的风险因素和后果。每年5次（半年） 2019-2023年进行的调查波，正在收集烟草和大麻产品使用的详细数据， 正在收集母公司R 01的主要目标和详细的SOGI数据，以获取有关 同伙本补编要求提供资金，以支付调查员和统计员的薪金， 为新的二次分析进行数据分析和手稿准备。补充的主要目的 一个项目是确定过去30天的烟草和大麻与各种SOGI的同时关联 青少年队列和年轻成人队列中的产品使用频率和多种用途状态。次级 目标是检查这些关联是否因个体而异， 时间顺序和种族/民族。因为我们反复测量了SOGI和烟草/大麻 使用，我们将分别为青少年和年轻成人队列提供多达14，843和9103个数据点， 将提供前所未有的力量来检查较低流行率的SOGI（例如，无性恋，泛性恋，质疑 性，性别非二进制）。在这个行政补充项目结束时，我们将有一些 对烟草和大麻产品使用中SOGI差异的最新、最具包容性和最详细的估计 在弱势群体AYA中。这将为以下方面提供信息：（a）减少SOGI癌症的精确公共卫生措施 差异;以及（B）国家烟草/大麻使用调查中是否需要对SOGI进行更具包容性的测量 因此，我们需要对“青年援助”项目进行评估，以避免忽视差异，从而忽视需要干预的群体。