CSUF and UCI-CFCCC Partnership for Cancer Health Disparities Research (1 of 2)

CSUF 和 UCI-CFCCC 癌症健康差异研究合作伙伴关系（1 of 2）

• 批准号: 10838835
• 负责人: Sora P Tanjasiri
• 金额: $ 52.52万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10838835
• 关键词: Acculturation; Address; Administrative Supplement; Adopted; Affect; Air; Air Pollutants; Air Pollution; American; Applications Grants; Area; Asian Americans; Asian ancestry; Behavior; Black race; California; Cambodian; Cancer Survivor; Cancer health equity; Cardiovascular system; Cessation of life; Characteristics; Chemicals; Child; Communities; Community Outreach; Comprehensive Cancer Center; Consumption; County; Diagnostic Services; Discrimination; Disparity; Eating Behavior; Educational Status; Elderly; Ethnic Origin; Ethnic Population; Exposure to; Family; Food; Food Chain; Frequencies; Funding; Future; Genetic Variation; Grant; Health; Health Disparities Research; Health Promotion; Health behavior; Health behavior and outcomes; Heat Exhaustion; Heat Stroke; Heat Waves; High temperature of physical object; Humidity; Hypertension; Immigrant; Income; Individual; Inequity; Infant; Infection; Infrastructure; Institution; Knowledge; Limited English Proficiency; Los Angeles; Malignant Neoplasms; Measures; Medical; Mental Health; Mentors; Meta-Analysis; Methods; Minority Groups; Morbidity - disease rate; Native Hawaiian or Other Pacific Islander; Neighborhoods; Non-Insulin-Dependent Diabetes Mellitus; Non-accidental; Oranges; Outcome; Ozone; Pacific Islander; Patient Self-Report; Perception; Persons; Pharmaceutical Preparations; Physical activity; Population; Populations at Risk; Poverty; Prevalence; Preventive care; Provider; Public Health; Race; Recommendation; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resources; Risk; Risk Behaviors; Scientist; Screening for cancer; Smoke; Smoking; Social isolation; Stress; Students; System; Talents; Temperature; Testing; Training Activity; Training and Education; Ultraviolet Rays; Unhealthy Diet; United States National Institutes of Health; Universities; Vietnamese; Vulnerable Populations; Wildfire; anticancer research; cancer diagnosis; cancer health disparity; cancer risk; cigarette smoking; climate change; climate-related health; community engaged research; coping; disorder risk; education research; environmental stressor; epidemiology study; ethnic diversity; experience; extreme heat; extreme temperature; fine particles; follow-up; fruits and vegetables; good diet; interest; low health literacy; low socioeconomic status; marginalized community; meter; mortality; parent grant; physical conditioning; population based; pressure; programs; psychologic; public health priorities; racial population; racism; risk mitigation; screening; screening services; social health determinants; stressor; structural determinants; substance use; toxicant; treatment services; undergraduate student; vulnerable community

Climate change is a growing public health priority and is considered a stress multiplier, placing pressures on vulnerable populations, regions, and systems. Soaring temperatures and wildfires are increasing in the western U.S. and the consequences are particularly dire in vulnerable groups including ethnic/racial communities and those of low socioeconomic status, the elderly, those who are socially isolated, and those with certain physical or mental health conditions. Approximately 23 million Americans are of self-reported Asian ancestry, and Asian American and Native Hawaiiian and Pacific Islander (AsA-NHPI) populations are the fastest growing subpopulation in the U.S. The AsA-NHPI populations are highly diverse in their disease risk profiles, such as prevalence of type 2 diabetes, hypertension, and major contributors to morbidity and mortality. They also experience disparities in multiple health outcomes, including lifetime cancer diagnosis, cigarette smoking, cancer screening behaviors, and healthy diet. These disparities are often hidden, because AsA-NHPI are frequently aggregated in large population-based epidemiological studies in the U.S., despite the genetic and ethnic diversity of AsA-NHPI populations. Furthermore, AsA-NHPI subpopulations (e.g. Cambodians, Vietnamese) experience high rates of poverty and low levels of education or have a high percentage of immigrants, which may increase vulnerability to climate change impacts. A substantial proportion of AsA-NHPI populations are also immigrants, which may impact people’s individual and neighborhood exposure to climate change exposure. Little is known about the exposure levels, health impacts, and coping capacity of the AsA-NHPI subpopulation for the climate change related exposures such as extreme heat and wildfires. This study examines the exposures to major climate change related stressors, potential health impacts, and community concerns and needs among AsA-NHPI populations in California’s Los Angeles and Orange counties. Using multi-methods, the aims include 1) characterizing exposure to extreme temperature and wildfire smoke over 19 years, 2) determining how exposures to heat and wildfire smoke contribute to cancer-related health outcomes, and 3) understanding the perceptions, concerns, and needs of AsA-NHPI subethnic groups to climate change and adaption. Results from this study will inform future R01 proposals that include adaptation testing to address community concerns and mitigate exposures to maximize cancer health equity.

气候变化是一个日益重要的公共卫生优先事项，被认为是一个压力倍增器， 对弱势群体、地区和系统的压力。高温和野火 在美国西部，这种情况正在增加，其后果在易受伤害的地区尤为严重。 包括族裔/种族社区和社会经济地位低的群体、老年人、 那些在社会上被孤立的人，以及那些有某些身体或精神健康状况的人。 大约有2300万美国人自称是亚裔， 夏威夷原住民和太平洋岛民（AsA-NHPI）人口增长最快 AsA-NHPI人群的疾病风险高度多样化 概况，如2型糖尿病、高血压的患病率，以及 发病率和死亡率。他们在多种健康结果方面也存在差异，包括 终生癌症诊断、吸烟、癌症筛查行为和健康饮食。 这些差异往往是隐藏的，因为AsA-NHPI经常聚集在大的 在美国进行的基于人群的流行病学研究尽管遗传和种族多样性， AsA-NHPI群体。此外，AsA-NHPI亚群（例如越南人、越南人） 贫困率高，教育水平低，或 移民，这可能会增加对气候变化影响的脆弱性。大幅 AsA-NHPI人群的比例也是移民，这可能会影响人们的个人 和邻里对气候变化的暴露。关于暴露的情况知之甚少 AsA-NHPI亚群对气候的水平、健康影响和应对能力 改变与极端高温和野火有关的暴露。本研究探讨的 暴露于与气候变化相关的主要压力源、潜在健康影响和社区 加州洛杉矶和橙子的AsA-NHPI人群的关注和需求 个县使用多种方法，目标包括：1）表征暴露于极端 温度和野火烟雾超过19年，2）确定如何暴露于热， 野火烟雾有助于癌症相关的健康结果，3）了解 AsA-NHPI亚种族群体对气候变化的看法、关切和需求， 适应这项研究的结果将为未来的R 01提案提供信息，包括适应性测试 解决社区关注的问题，减少暴露，以最大限度地提高癌症健康公平性。