Central Africa International Epidemiology databases to Evaluate AIDS

项目摘要/摘要 IeDEA网络旨在调查气候、季节波动和极端天气对 艾滋病毒护理结果。目前的数据并不能完全解释护理方面的差距、护理参与度和护理损失 由IeDEA收集。与气候有关的数据目前正在被纳入IeDEA数据，如天气和 气候直接和间接影响这些结果，特别是在基础设施有限和高度发达的地区。 粮食不安全。这项研究旨在探索极端天气事件与艾滋病毒服务之间的联系 世界各地接受艾滋病毒护理的人的利用和护理结果。 为实现这一目标，中部非洲开发署区域编写了一份补充提案，以支持这一工作 IeDEA全球调查的新领域。IeDEA网络包括2个以上的纵向开放队列数据 自2004年以来，来自44个国家450多家诊所的100万艾滋病毒携带者。用于此的气候数据集 工作包括从20世纪80年代初开始的每日温度和降雨量信息，以便进行分析 在提供艾滋病毒护理服务之前和期间的气候暴露情况。这项补充建议将有所帮助 加快这项工作，并聘请更多的多学科调查人员专注于气候和健康 在全球IeDEA网络内进行研究。 补充项目有三个主要目标：目标1：创建一个气候与健康科学兴趣小组 在IeDEA内；目标2：将极端天气事件(EWE)暴露变量用于艾滋病毒护理结果 研究；目标3：对母羊和艾滋病毒护理结果之间的关系进行初步分析 IeDEA网络。提议的目标在母方赠款的范围内：中部非洲国际开发署的目标3 Parent Grant表示，我们将“领导和支持全球IeDEA研究议程”。 这项拟议的工作将建立一个全球调查人员社区和一个研究协作平台 关于气候和艾滋病毒护理结果。该项目将促进交流想法、气候数据集和工具 在不同的调查团队之间。一项补充提供的支助将有助于产生初步的 分析R01提案，并与对气候和艾滋病毒感兴趣的IeDEA调查人员接触。这项研究 将与气候可能起作用的其他健康状况相关。拟议的研究是 在NOT-HD-23-006的“健康影响研究”和“能力建设”支柱下作出反应。

Project Summary/Abstract The IeDEA network aims to investigate the impact of climate, seasonal fluctuations, and extreme weather on HIV care outcomes. Gaps in care, engagement in care, and loss to care are not fully explained by current data collected by IeDEA. Climate-related data are currently being incorporated into IeDEA data, as weather and climate directly and indirectly influence these outcomes, especially in areas with limited infrastructure and high food insecurity. The study aims to explore associations between extreme weather events and HIV service utilization and care outcomes among people receiving HIV care around the world. To achieve this, a supplement proposal has been prepared by the Central African IeDEA region to support this new area of global investigation in IeDEA. The IeDEA network includes longitudinal open cohort data on over 2 million people with HIV from more than 450 clinics in 44 countries since 2004. The climate dataset used for this work includes daily temperature and rainfall information onward from the early 1980s, allowing for the analysis of climate exposures before and during the provision of HIV care services. This supplement proposal will help accelerate this work and engage a larger group of multidisciplinary investigators to focus on climate and health research within the global IeDEA network. The supplement project has three main aims: Aim 1: Create a climate and health scientific interest group within IeDEA; Aim 2: Operationalize extreme weather event (EWE) exposure variables for HIV care outcome studies; Aim 3: Conduct preliminary analyses of associations between EWEs and HIV care outcomes in the IeDEA network. The proposed aims are within the scope of the parent grant: Aim 3 of the Central Africa IeDEA parent grant states that we will ‘lead and support a global IeDEA research agenda’. This proposed work will establish a global community of investigators and a platform for research collaboration on climate and HIV care outcomes. The project will facilitate the sharing of ideas, climate datasets, and tools across different teams of investigators. The support provided by a supplement will help to generate preliminary analyses for R01 proposals and engage with IeDEA investigators interested in climate and HIV. This research will have relevance to other health conditions for which climate may play a role. The proposed research is responsive under the ‘Health Effects Research’ and ‘Capacity Building’ pillars of NOT-HD-23-006.