Training a new generation of vaccinologists

培训新一代疫苗学家

• 批准号: 10838018
• 负责人: Nadine Georges Rouphael
• 金额: $ 9.02万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10838018
• 关键词: Generations; Training

This is a renewal application for the third cycle (years 11-15) of the established Emory Vaccinology Training Program T32 (VTP-T32) which was initiated in 2009. Emory University continues to be uniquely positioned to train a cadre of basic, translational, and clinical scientists with cutting edge, multi-disciplinary expertise in vaccinology-related research. The faculty preceptors have the breadth of expertise and mentoring experience that are critical for training a new generation of vaccinologists. All preceptors are affiliated with departments and programs at Emory, which include the Emory Schools of Medicine and Public Health, the Emory Vaccine Center and the joint Emory-Georgia Institute of Technology Biomedical Engineering (BME) Department at Emory. The preceptors have extensive training experience across varied vaccinology disciplines, including microbiology, immunology, infectious diseases, public health, pathology, pediatrics, epidemiology, behavior, global health, implementation science, and health policy. The fellows receive formal and informal education, career mentoring, and conduct mentored research. Our trainees acquire the skills and background necessary to succeed as future vaccinology leaders. Each trainee selects an in depth mentored research project with a preceptor from one of six Research Training Sections: 1) Pathogenesis & Vaccine Discovery; 2) Innate & Adaptive Immunity (immune responses to bacterial, protozoal, & viral antigens); 3) Translation & Delivery; 4) Vaccine Epidemiology & Clinical Trials; 5) Implementation Science & Health Policy; 6) Vaccine Safety (a dedicated CDC funded slot). Every trainee participates in two required comprehensive graduate level courses emphasizing different aspects of vaccinology, and the third required course in Responsible Conduct of Research (Ethics). The specific goals are: The specific aims of the Emory VTP-T32 include: 1- To continue implementing our systematic approach for identifying, recruiting and retaining superb motivated, and diverse post-doctoral trainees into the VTP-T32. 2- To provide each trainee with the best formal and informal vaccinology education, a robust mentored research project, and career mentoring. 3- To continue integrating the strong basic science, translational research, implementation science, clinical trials, and vaccine policy programs at Emory into a multi-faceted training experience, producing a synergistic whole greater than the sum of its individual parts.

这是埃默里大学第三个周期（11-15 年）的续签申请 疫苗学培训计划 T32 (VTP-T32) 于 2009 年启动。埃默里大学 继续在培养基础科学家、转化科学家和临床科学家骨干方面处于独特的地位 拥有疫苗学相关研究领域的前沿、多学科专业知识。 教师导师拥有至关重要的广泛专业知识和指导经验 用于培训新一代疫苗学家。所有导师均隶属于部门 和埃默里大学的项目，其中包括埃默里医学院和公共卫生学院、 埃默里疫苗中心和埃默里-佐治亚理工学院生物医学联合研究所 埃默里大学工程（BME）系。导师们拥有丰富的培训经验 跨越不同的疫苗学学科，包括微生物学、免疫学、传染病、 公共卫生、病理学、儿科、流行病学、行为、全球健康、实施 科学和卫生政策。 研究员接受正式和非正式的教育、职业指导和行为指导 研究。我们的学员获得未来成功所需的技能和背景 疫苗学领导者。每个学员都会选择一个深入指导的研究项目 六个研究培训部门之一的导师：1) 发病机制和疫苗发现； 2) 先天性和适应性免疫（对细菌、原虫和病毒抗原的免疫反应）； 3） 翻译与交付； 4) 疫苗流行病学与临床试验； 5) 实施科学与 卫生政策； 6) 疫苗安全（CDC 资助的专门项目）。每位学员都参与 两门必修的综合研究生水平课程，强调不同方面 疫苗学，以及负责任的研究行为（道德）的第三门必修课。这 具体目标是： Emory VTP-T32 的具体目标包括： 1- 继续实施我们的系统方法来识别、招聘和保留 积极进取且多样化的博士后学员进入 VTP-T32。 2- 为每位学员提供最好的正式和非正式疫苗学教育、健全的 指导研究项目和职业指导。 3- 继续整合强大的基础科学、转化研究、实施 埃默里大学的科学、临床试验和疫苗政策项目成为多方面的培训 经验，产生一个协同整体，大于其各个部分的总和。

项目成果

Young Adult Human Papillomavirus and Influenza Vaccine Coverage: A Comparison Across College Enrollment Status.

• DOI: 10.1007/s10900-020-00833-9
• 发表时间: 2021-03
• 期刊: Journal of community health
• 影响因子: 5.9
• 作者: Mathewson K;Sundaram M;Bednarczyk RA
• 通讯作者: Bednarczyk RA

Marvelous but Morbid: Infective endocarditis due to Serratia marcescens.

• DOI: 10.1097/ipc.0000000000000360
• 发表时间: 2016-05
• 期刊: Infectious diseases in clinical practice (Baltimore, Md.)
• 作者: Phadke VK;Jacob JT
• 通讯作者: Jacob JT

Improving health outcomes for IPV-exposed women living with HIV.

改善暴露于 IPV 且感染 HIV 的女性的健康状况。

• DOI: 10.1097/qai.0b013e3182a29f1b
• 发表时间: 2013
• 期刊: Journal of acquired immune deficiency syndromes (1999)
• 作者: Wingood,GinaM;DiClemente,RalphJ;Seth,Puja
• 通讯作者: Seth,Puja

High prevalence of lipopolysaccharide mutants and R2-Pyocin susceptible variants in Pseudomonas aeruginosa populations sourced from cystic fibrosis lung infections.

源自囊性纤维化肺部感染的铜绿假单胞菌群体中脂多糖突变体和 R2-Pyocin 敏感变异体的患病率很高。

• DOI: 10.1101/2023.04.26.538445
• 发表时间: 2023
• 期刊: bioRxiv : the preprint server for biology
• 作者: Mei,Madeline;Pheng,Preston;Kurzeja-Edwards,Detriana;Diggle,StephenP
• 通讯作者: Diggle,StephenP

The half-life of maternal transplacental antibodies against diphtheria, tetanus, and pertussis in infants: an individual participant data meta-analysis.

• DOI: 10.1016/j.vaccine.2021.12.007
• 发表时间: 2022-01-24
• 期刊: VACCINE
• 影响因子: 5.5
• 作者: Oguti, Blanche;Ali, Asad;Andrews, Nick;Barug, Daan;Duc Anh Dang;Halperin, Scott A.;Ha Thi Thu Hoang;Holder, Beth;Kampmann, Beate;Kazi, Abdul M.;Langley, Joanne M.;Leuridan, Elke;Madavan, Naomi;Maertens, Kirsten;Maldonado, Herberth;Miller, Elizabeth;Munoz-Rivas, Flor M.;Omer, Saad B.;Pollard, Andrew J.;Rice, Thomas F.;Rots, Nynke;Sundaram, Maria E.;Wanlapakorn, Nasamon;Voysey, Merryn
• 通讯作者: Voysey, Merryn