California Clinical and Translational Pain Research Consortium

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Abstract The University of California Clinical and Transla�onal Pain Research Consor�um (CCTPRC) was awarded the NIH U24 (NS115714) grant in 2019. The budget was reduced when the U24 was awarded. This required us to reduce effort for the Inves�gators, PM and study coordinator. Although we were able to streamline the efficiency and costs by combining redundancy between other NIH HEAL grants across the CCTPRC, the higher-than-expected screen/screen failure ra�o for the EN20-01 and EN21-01 studies strained the budget with funds running out March 2024. We are asking for addi�onal funds to get us through the 5-year budget period. We will use the funds toward other recruitment methods for the two studies u�lizing bioinforma�cs to search the EHR for qualified subjects. Two methods will be used, batch emailing and cold calls. We will monitor success of screen to randomiza�on ra�o and revert to the method yielding the highest randomiza�ons. This will also allow us to refined recruitment efforts for future EPPIC-Net studies.