Data Coordinating Center for Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)
预防急性至慢性背痛的脊柱手法和患者自我管理数据协调中心 (PACBACK)
基本信息
- 批准号:10895775
- 负责人:
- 金额:$ 13.82万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-01 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:AcuteAddressAdultAffectBackBehaviorBehavioralCaringChronic low back painDataData Coordinating CenterDissemination and ImplementationDrug usageEffectivenessEnrollmentGuidelinesHealth OccupationsHealthcareHybridsInterventionLow Back PainMedicalMethodsNational Center for Complementary and Integrative HealthOpioidOverdosePain managementPatientsPharmaceutical PreparationsPharmacotherapyPreventionPsychosocial FactorRandomizedRecommendationRecoveryResearchRisk FactorsRoleScreening procedureSecondary PreventionSelf ManagementSocietiesSpinal ManipulationStrategic PlanningStructureSubgroupTestingTranslatingTranslationsaddictionbiopsychosocialchronic back painchronic painchronic painful conditionclinical practicecostdesigndisabilityeffectiveness evaluationempowermentfuture implementationhigh riskimplementation strategyimprovednondrug therapynovelopioid misusepain chronificationpain reductionpain-related disabilitypreventprimary outcomeproductivity losspublic health prioritiesrandomized trialsecondary outcometargeted treatmentuptake
项目摘要
SUMMARY. The US is in the midst of an unprecedented pain management crisis. Low back pain (LBP) is the
most common chronic pain condition in adults and the leading cause of disability worldwide. Guidelines have
recommended non-pharmacologic treatments like spinal manipulation and behavioral approaches for LBP for
nearly a decade, however uptake in practice has been poor. Little is known about the role of these treatments
in secondary prevention of chronic LBP (cLBP), especially for patients with biopsychosocial risk factors. With
burgeoning costs of cLBP and mounting evidence of ineffectiveness and harms of commonly used drug
treatments, including opioids, there is a critical need for research on non-pharmacological treatments for cLBP
prevention that can be readily translated to practice.
The long-term objective is to reduce overall LBP burden by testing scalable first-line non-pharmacologic
strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to cLBP.
We propose a novel randomized hybrid trial addressing both effectiveness and implementation. A total of 1000
patients will be enrolled with nonspecific LBP of 2-12 weeks duration, at medium and high risk of developing
cLBP using the Subgroups for Targeted Treatment (STarT) Back Screening Tool (SBST). Aim 1 will assess
the effectiveness of Spinal Manipulation Therapy (SMT), Structured Self-Management (SSM), and SMT+SSM
relative to Usual Medical Care (UMC) in a randomized trial using a 2x2 factorial design. Primary outcomes are
cLBP Impact at 12 months; and cumulative reduction of pain and disability over 1 year. Secondary outcomes
include recovery from acute/sub-acute LBP at 6 months, PROMIS-29, productivity loss, health care use, and
medication use (including opioids). Aim 2: will use mixed methods to gather data about important influences
on the interventions that could affect results interpretation and future implementation.
Aligned with the National Center for Complementary and Integrative Health’s (NCCIH) Strategic Plan 2016, this
project has the potential to significantly transform LBP management by providing definitive and generalizable
evidence regarding front-line non-pharmacologic interventions addressing physical and psychosocial factors
for the prevention of cLBP. By empowering patients to engage in healthy pain management behaviors, we
anticipate LBP related disability, productivity loss, and reliance on continued health care and medication use
(including opioids) will be reduced. The comprehensive dissemination and implementation strategy, informed
by major stakeholders, will facilitate translation into clinical practice across health professions.
总结。美国正处于一场前所未有的疼痛管理危机之中。腰痛(LBP)是
项目成果
期刊论文数量(0)
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{{ truncateString('PATRICK J HEAGERTY', 18)}}的其他基金
Data Coordinating Center for Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)
预防急性至慢性背痛的脊柱手法和患者自我管理数据协调中心 (PACBACK)
- 批准号:
10226960 - 财政年份:2017
- 资助金额:
$ 13.82万 - 项目类别:
Data Coordinating Center for Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)
预防急性至慢性背痛的脊柱手法和患者自我管理数据协调中心 (PACBACK)
- 批准号:
10460354 - 财政年份:2017
- 资助金额:
$ 13.82万 - 项目类别:
Data Coordinating Center for Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)
预防急性至慢性背痛的脊柱手法和患者自我管理数据协调中心 (PACBACK)
- 批准号:
9923235 - 财政年份:2017
- 资助金额:
$ 13.82万 - 项目类别:
High-dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) DCC
高剂量促红细胞生成素治疗窒息和脑病 (HEAL) DCC
- 批准号:
9174290 - 财政年份:2016
- 资助金额:
$ 13.82万 - 项目类别:
High-dose Erythropoietin for Asphyxia and Encephalopathy (HEAL) DCC
高剂量促红细胞生成素治疗窒息和脑病 (HEAL) DCC
- 批准号:
9355476 - 财政年份:2016
- 资助金额:
$ 13.82万 - 项目类别:
Preterm Epo Neuroprotection Trial (PENUT Trial) DCC
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$ 13.82万 - 项目类别:
Preterm Epo Neuroprotection Trial (PENUT Trial) DCC
早产儿 Epo 神经保护试验(PENUT 试验)DCC
- 批准号:
8497375 - 财政年份:2013
- 资助金额:
$ 13.82万 - 项目类别:
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