MULTIMODAL FUNCTIONAL MAPPING SYSTEM FOR EPILEPSY

癫痫多模式功能映射系统

• 批准号: 2038550
• 负责人: VLADIMIR G IVANOV
• 金额: $ 10万
• 依托单位: TELEFACTOR CORPORATION
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-15 至 1997-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2038550
• 关键词: biomedical equipment development; brain electrical activity; brain mapping; clinical biomedical equipment; computed axial tomography; electroencephalography; epilepsy; evoked potentials; magnetic resonance imaging; method development

(Investigator's Abstract): A two phase project is described which will permit extending the performance of 64-128 channel EEG telemetry systems which are normally used for long-term monitoring of patients with indwelling intracranial electrodes. The extended performance will include functional mapping (FM) of cortical areas of the brain by three techniques: recording behavioral response to electrical stimulation of intracranial electrodes, evoked potential mapping and functional-MRI. The final product will combine this functional mapping with existing techniques for the mapping of regions that are dysfunctional by reason of epileptiform electrical activity and integrating the display with anatomical mapping via MRI or CAT to provide a complete, integrated workstation for evaluation and surgical planning for epilepsy. A major advantage of the proposed system is that it will be designed to economically "Piggy-Back" additional clinical functions on a large, already installed base of high-resolution monitoring systems, without disrupting their primary clinical function of detecting and recording epileptiform events.

（研究者摘要）：描述了一个两阶段的项目， 将允许扩展64-128通道EEG的性能 通常用于长期监测的遥测系统 颅内电极留置的患者。 扩展 性能将包括皮层区域的功能映射（FM） 通过三种技术：记录行为反应， 颅内电极电刺激，诱发的 电位标测和功能MRI。 最终产品将 联合收割机将该功能映射与现有技术相结合， 由于癫痫样发作而功能失调的区域的映射 电活动和整合显示与解剖 通过MRI或CAT进行映射，以提供完整、集成的 癫痫的评估和手术计划工作站。 拟议系统的一个主要优点是， 旨在经济地“搭载”额外的临床 在已经安装的大量高分辨率 监测系统，而不中断其主要临床 检测和记录癫痫样事件的功能。

项目成果

A new procedure for experimental autoimmune uveitis with small uveitogenic peptides.

使用小葡萄膜肽治疗实验性自身免疫性葡萄膜炎的新方法。

• DOI: 10.1080/09273940600899684
• 发表时间: 2006
• 期刊: Ocular immunology and inflammation
• 影响因子: 3.3
• 作者: Sery,TheodoreW;Su,Ying-Hsiu;EagleJr,Ralph;Ueda,Masumi;Yamamoto,Nobuto
• 通讯作者: Yamamoto,Nobuto