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SELECTIVE ATTENTION ASYMMETRIES IN SCHIZOPHRENIA

SELECTIVE ATTENTION ASYMMETRIES IN SCHIZOPHRENIA
精神分裂症的选择性注意力不对称
批准号:
6032996
负责人:
Joseph I. Tracy
金额:
$1.37万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1996
资助国家:
美国
项目状态:
已结题
起止时间:
1996-04-01 至 1999-03-31

项目摘要

项目成果

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中文摘要
翻译
最近一项关于精神分裂症患者选择性注意操作的研究
英文摘要
A recent study of selective attention operations in schizophrenia reported subtle right visual field (RVF) hemineglect in a sample of non- chronic schizophrenics (Posner et al, 1988). This finding stimulated speculation about specific lateralized lesions (left parietal and/or left anterior) and attentional operations (i.e., diminished left hemisphere ability to generate preparatory sets) in schizophrenia. These findings were also used to explain other attention abnormalities in schizophrenia (i.e., vigilance). Replication of this important finding is needed to ensure that model building activity in selective attention is on solid ground. Also, determination of the mechanism underlying the finding is needed for accurate neuroanatomical theory and further research on its diagnostic or etiologic value. Specifically, the hemineglect may be caused by a failure in stimulus selection, i.e., filtering, or an inability to generate attentional gradients, which play a key role in generating preparatory, expectational sets. Finally, the temporal stability of deficits in selective attention have not been established and their relation to neuroleptic medication and clinical state have yet to be defined. This project will replicate the Posner et al. (1988) study and assess performance on a shape identification, i.e., filtering, task (LaBerge and Brown, 1989) through a four group, repeated measures design (N=120; baseline, 3 and 6 month assessments). Chronic schizophrenics on one of three neuroleptic regimens (clozapine, risperidone, prolixin decanoate, n's=30) and normal controls (n=30) will be followed for six months. Patients will remain on the same neuroleptic throughout the study. Serial assessments will also be taken of psychiatric symptoms, cognitive status, and gross hemineglect. The three schizophrenic groups will be matched on duration of illness. All four groups will be matched on age and gender. The hemineglect hypothesis will be tested along with tests of an early filtering mechanism for visual shape, and the ability to generate attentional gradients.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
The selective effects of alcohol on automatic and effortful memory processes.
酒精对自动和努力记忆过程的选择性影响。
DOI: 10.1037//0894-4105.13.2.282
发表时间: 1999
期刊: Neuropsychology.
影响因子: --
作者: [Tracy,JI, Bates,ME]
通讯作者: Bates,ME
A comparison of memory for verbal and non-verbal material in schizophrenia.
精神分裂症患者言语和非言语材料记忆的比较。
DOI: 10.1016/s0920-9964(01)00241-9
发表时间: 2001
期刊: Schizophrenia research
影响因子: 4.5
作者: [Tracy,JI, Mattson,R, King,C, Bundick,T, Celenza,MA, Glosser,G]
通讯作者: Glosser,G
Test of a potential link between analytic and nonanalytic category learning and automatic, effortful processing.
测试分析性和非分析性类别学习与自动、努力的处理之间的潜在联系。
DOI: 10.1006/brcg.2001.1288
发表时间: 2001
期刊: Brain and cognition.
影响因子: --
作者: [Tracy,JI, Pinsk,M, Helverson,J, Urban,G, Dietz,T, Smith,DJ]
通讯作者: Smith,DJ
Information-processing characteristics of explicit time estimation by patients with schizophrenia and normal controls.
精神分裂症患者和正常对照者显式时间估计的信息处理特征。
DOI: 10.2466/pms.1998.86.2.515
发表时间: 1998
期刊: Perceptual and motor skills.
影响因子: --
作者: [Tracy,JI, Monaco,C, McMichael,H, Tyson,K, Chambliss,C, Christensen,HL, Celenza,MA]
通讯作者: Celenza,MA
Identify abnormal neurocognitive circuits in temporal lobe epilepsy
  • 批准号:
    7315309
  • 项目类别:
  • 资助金额:
    $20.34万
  • 财政年份:
    2007
  • 负责人:
    Joseph I. Tracy
  • 依托单位:
海外基金