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Mechanisms of glucocorticoid resistance in acute lymphoblastic leukaemia

Mechanisms of glucocorticoid resistance in acute lymphoblastic leukaemia
急性淋巴细胞白血病糖皮质激素抵抗机制
批准号:
nhmrc : 568695
负责人:
A/Pr Jeffrey Craig
金额:
$36.54万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31

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中文摘要
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英文摘要
Glucocorticoids are extremely active drugs used in the treatment of childhood acute lymphoblastic leukaemia (ALL), yet a proportion of patients respond poorly to therapy and exhibit resistance at relapse. Clinically relevant mechanisms of glucocorticoid resistance are poorly understood, principally due to lack of appropriate experimental models. This project will reveal novel mechanisms of drug resistance in childhood leukaemia and lead to novel therapeutic strategies to improve outcome.
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会议论文
Unravelling the impact of an energy-rich environment on susceptibility and resistance to obesity
  • 批准号:
    nhmrc : 1060173
  • 项目类别:
    Project Grants
  • 资助金额:
    $53.13万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Jeffrey Craig
  • 依托单位:
THE CYCLE OF OBESITY: Two generations of a pregnancy cohort to investigate obesity epigenetics
  • 批准号:
    nhmrc : 1059711
  • 项目类别:
    Project Grants
  • 资助金额:
    $74.53万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Jeffrey Craig
  • 依托单位:
Australian Centre of Excellence in Twin Research
  • 批准号:
    nhmrc : GNT1079102
  • 项目类别:
    Centres of Research Excellence
  • 资助金额:
    $247.54万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Jeffrey Craig
  • 依托单位:
Australian Centre of Excellence in Twin Research
  • 批准号:
    nhmrc : 1079102
  • 项目类别:
    Centres of Research Excellence
  • 资助金额:
    $172.14万
  • 财政年份:
    2014
  • 负责人:
    A/Pr Jeffrey Craig
  • 依托单位:
国内基金
海外基金
盐皮质激素受体抑制2型固有淋巴细胞活化加重心肌梗死后心室重构的作用机制
  • 批准号:
    82372202
  • 项目类别:
    面上项目
  • 资助金额:
    49.00万元
  • 批准年份:
    2023
  • 负责人:
    侯旭敏
  • 依托单位: