Cognitive Consequences of the Stress Response

压力反应的认知后果

• 批准号: 6523319
• 负责人: PEGGY J JENNINGS
• 金额: $ 8.08万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2003-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6523319
• 关键词: clinical research; cognition; female; human subject; memory; neural information processing; psychomotor reaction time; relaxation; stress; stress management; verbal learning

DESCRIPTION: (provided by applicant) The Specific Aims of this study are to explore changes in cognitive processes associated with acute stress. The proposed study extends previous research suggesting that acute stress is associated with (a) a shift in cognitive processes, favoring enhanced reaction time and short-term memory at the expense of long-term memory consolidation, and (b) enhanced automatic cognitive processes and habitual responses. These Specific Aims are intended to elucidate the cognitive processes that may be associated with relapse (Specific Aim 1) and successful recovery (Specific Aim 2) from drug addiction. Specific Aim 1. Acute stress may facilitate the automatic cognitive processes that support habitual responses. Experiment 1 tests the hypothesis that acute stress is associated with enhanced automatic cognitive processes and reduced effortful cognitive processes. Using a well-established stress-induction paradigm (and a control condition) participants will complete cognitive tasks that allow dissociation of the influences of automatic and conscious (effortful) processes on cued recall of verbal material. This experiment will examine psychological, autonomic, and neuroendocrine indicators of acute stress and their relations with measures of automatic and effortful processes. Specific Aim 2. Previous research has established that acute stress is associated with enhanced reaction time and short-term memory at the expense of long-term memory consolidation. A state of relaxation, in contrast to acute stress, may be associated with a mode of cognitive processing that supports effortful, long-term, and declarative processes. Experiment 2 tests the hypothesis that an acute state of relaxation using a stress-reduction technique will be associated with enhanced long-term memory consolidation and reduced reaction speed and short-term memory' capacity.

描述：（由申请人提供） 这项研究的具体目的是探索认知过程的变化 与急性应激有关。拟议的研究扩展了先前的研究 表明急性压力与（a）认知能力的转变有关 过程，有利于增强反应时间和短期记忆，但代价是 长期记忆巩固，以及（b）增强自动认知 过程和习惯性反应。这些具体目标旨在阐明 可能与复发相关的认知过程（具体目标 1） 以及从毒瘾中成功康复（具体目标 2）。 具体目标 1. 急性压力可能促进自动认知过程 支持习惯性反应。实验 1 检验了以下假设：急性 压力与自动认知过程的增强和减少有关 努力的认知过程。使用完善的压力诱导 范例（和控制条件）参与者将完成认知任务 允许分离自动和有意识的影响 根据提示回忆口头材料的（费力的）过程。这个实验将 检查急性应激的心理、自主神经和神经内分泌指标 以及它们与自动和努力过程的测量的关系。 具体目标 2. 先前的研究已经证实，急性应激是 与增强反应时间和短期记忆有关 长期记忆巩固。与急性状态相反的放松状态 压力，可能与支持的认知处理模式有关 努力的、长期的、声明性的过程。实验2测试了 假设使用减压技术的急性放松状态 将与增强的长期记忆巩固和减少有关 反应速度和短期记忆能力。