Low-Cost Device for Digital Retinal Imaging

用于数字视网膜成像的低成本设备

• 批准号: 6726728
• 负责人: ANN E ELSNER
• 金额: $ 60.42万
• 依托单位: SCHEPENS EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6726728
• 关键词: adult human (21+); bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; digital imaging; eye disorder diagnosis; human subject; imaging /visualization /scanning; lasers; macular degeneration; pupillography; retina; retinography

DESCRIPTION (provided by applicant): We plan a low cost, simple-to use-device for imaging the human macula in a broad variety of patients, a Laser Scanning Digital Camera (LSDC). Our goal is for the basic LSDC to have an up front, one-time cost less than 10% of the total price of current high end devices, without a decrement in image quality but with superior ease of use. The resulting LSDC should be considered as much an ophthalmoscope as a camera, since current ophthalmoscopes are often poorly used by non eye-care specialists. This work is derived from over 15 years of experience in imaging the human retina with a comfortable and safe level of near infrared light, as well as visible wavelength light, using laboratory instrumentation built by the P.I. Commercially developed instruments in a clinical setting led to further applications. It became clear that a digital retinal imaging device was needed that does not require the use of eye drops to dilate the pupils. This led to considerable thought about what features were absolutely necessary, and how such a device could be simplified over commercially available instruments. The LSDC will work like an off-the-shelf digital camera for use by non-experts in the eye care field. It will be operated in a non-invasive, non-contact manner, without the need for drops to dilate the pupil of the eye. Our usability studies indicated that without training, even physicians could not determine the procedure to use high-end instruments: they wasted a large amount of time staring at the computer screen, where no directions appeared. Ease of use is improved by eliminating the dedicated ancillary computer and image acquisition system, which require supporting electronics and proprietary computer software. Device complexity, weight, size, and consequently cost are also reduced. A device is truly low-cost only if it can withstand use and minimal training for use is needed. Thus, cords and external power supplies that are easily broken will eliminated, and the planned device can be ruggedly packaged. Our proposed digital camera approach, combined with an onboard and web-based database of eye diseases, reduces training to almost a cook-book approach. This proposal builds our initial work aimed a trauma to include a broader range of maculopathies, including those affecting adults and pediatric patients. The broader range of eye problems and the smaller eye size of children require instrumentation research in the optimization of optics and construct validity. Finally, we will examine the image quality of this low cost LSDC for functions such as angiography.

描述(由申请人提供)： 我们计划一种低成本、简单易用的设备，用于在各种患者中对人类黄斑进行成像，即激光扫描数码相机(LSDC)。我们的目标是让基本LSDC的前期一次性成本低于当前高端设备总价的10%，而且不会降低图像质量，但具有极好的易用性。由此产生的LSDC应该被视为与相机一样的检眼镜，因为目前的检眼镜通常不被非眼科专家使用得很差。这项工作源于15年多来使用P.I.建造的实验室仪器，使用舒适而安全的近红外光和可见光对人类视网膜进行成像的经验。商业开发的仪器在临床环境中带来了进一步的应用。很明显，需要一种不需要使用眼药水来扩大瞳孔的数字视网膜成像设备。这引发了人们对哪些功能是绝对必要的，以及这样的设备如何比商业仪器更简单的思考。LSDC将像一台现成的数码相机一样工作，供眼部护理领域的非专家使用。它将以非侵入性、非接触性的方式进行操作，不需要滴眼剂来扩大眼睛的瞳孔。我们的可用性研究表明，在没有培训的情况下，即使是医生也无法确定使用高端仪器的程序：他们浪费了大量时间盯着电脑屏幕，那里没有任何说明。通过取消需要支持电子设备和专有计算机软件的专用辅助计算机和图像采集系统，提高了易用性。设备的复杂性、重量、尺寸以及因此的成本也降低了。只有当设备经得起使用并且只需要最少的使用培训时，它才是真正的低成本设备。因此，容易损坏的电线和外部电源将被淘汰，计划中的设备可以进行坚固的包装。我们建议的数码相机方法，结合机载和基于网络的眼病数据库，将培训减少到几乎是食谱的方法。这项提案建立了我们最初的工作，旨在将创伤纳入更广泛的黄斑病变，包括那些影响成人和儿童患者的疾病。儿童的眼睛问题范围更广，眼睛更小，这就要求在光学和结构效度的优化方面进行仪器研究。最后，我们将检查这种低成本LSDC的图像质量，以实现血管造影等功能。