Low-Cost Device for Digital Retinal Imaging

用于数字视网膜成像的低成本设备

• 批准号: 7833292
• 负责人: ANN E ELSNER
• 金额: $ 37.95万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2011-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7833292
• 关键词: Adult; Age; Anterior; Area; Beds; Blindness; Blood Vessels; Blurred vision; Caring; Cataract; Clinical Research; Complications of Diabetes Mellitus; Computers; Computing Methodologies; Contracts; Cystoid Macular Edema; Data; Databases; Detection; Devices; Diabetes Mellitus; Diabetic Retinopathy; Diagnostic Imaging; Dilatation - action; Disadvantaged; Early Diagnosis; Edema; Electronics; Elements; Engineering; Ethnic group; Exudate; Eye; Eye Color; Eyeglasses; Fiber; Fixed Pupils; Funding; Fundus; Gender; Glass; Goals; Height; Housing; Hybrids; Image; Imagery; Imaging Device; Imaging Techniques; Individual; Investigation; Iris; Knowledge; Lasers; Lead; Lesion; Light; Lighting; Maps; Measurement; Measures; Mechanics; Methods; Microaneurysm; Microscopy; Minority; Miosis disorder; Morphologic artifacts; Motor; Mydriasis; Mydriatics; National Institute of Biomedical Imaging and Bioengineering; Ophthalmoscopes; Optics; Outcome; Patients; Performance; Photography; Pigmentation physiologic function; Positioning Attribute; Price; Production; Provider; Pupil; Quality Control; Reading; Records Controls; Recovery; Refractive Errors; Reproducibility; Research; Resolution; Retina; Retinal; Retinal Detachment; Retinal Diseases; Risk; Scanning; Screening procedure; Series; Severities; Shapes; Signal Transduction; Solutions; Source; Specialist; Staging; Structure; Students; Surface; Surrogate Markers; System; Techniques; Technology; Testing; Time; Traction; Training; United States National Institutes of Health; Variant; Vision; Work; base; bioimaging; cost; cost effective; data acquisition; design; detector; diabetic; diabetic cataract; diabetic patient; digital; digital imaging; experience; field study; flexibility; health disparity; improved; instrument; instrumentation; laptop; light scattering; macula; macular edema; medical specialties; minority subjects; neovascularization; new technology; novel; novel strategies; older patient; optical communication; parent grant; public health relevance; relating to nervous system; sensor; voltage

DESCRIPTION (provided by applicant): This proposal will accelerate the tempo of scientific research of NIBIB RO1 EB002346, "Low-Cost Device for Digital Retinal Imaging," by means of Notice Number (NOT-OD-09-058) under the Notice Title: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications. We are enhancing our novel design for a low cost Laser Scanning Digital Camera (LSDC), for use in diabetic retinopathy screening without pupil dilatation, by adding a motor and sensor on our focusing state that will provide the potential for autofocus, which will assist operators with little experience. Reducing the cost of operators is important in the per use cost of the device, allowing screening to be accomplished in a more cost effective manner. To reach the underserved, the LSDC does not require pupil dilation and yet provides a high contrast, digital image. The LSDC is designed to work well with small pupils and comfortable light level, producing continuous images to assist the operator during data acquisition. The use of near Infrared illumination provides this high contrast in all eye colors, so that minority subjects who have dark eyes still readily imaged with comfortable light levels. The proposed new autofocus feature automatically adds the potential for the LSDC serving as an autorefractor, a cataract detection device, and a retinal topographer to detect macular edema in an objective manner. We will test and optimize this device in subjects with a wide range of refractive errors and eye color, patients with cataract, and diabetic patients with retinopathy including macular edema. We will compare performance with that of age-matched and gender-matched normal control subjects. We will also compare the results of the new technology to that of high end devices, such as the IOL Master, spectral domain OCT, and wavefront aberrations. Our main goal is to provide high contrast retinal images in patients of all ethnic groups and including older patients for purposes of detection of diabetic retinopathy. The added functionality leads to greater energy efficiency because several functions can be accomplished in one instrument, saving on power, part count, footprint, and patient chair time. The data produced by this instrument will also provide a wealth of information to be used in the training of students. PUBLIC HEALTH RELEVANCE: We will modify our low cost retinal imaging device, the Laser Scanning Digital Camera, to investigate a low cost method to improve operator focus, measure refraction, investigate eye shape, quantify cataract, and quantify the severity of macular edema. Once developed, increased the functionality requires minimal added cost, providing energy efficiency by combining functions into a single device.

描述（由申请人提供）：本提案将通过通知标题下的通知编号（NOT-OD-09-058）加快NIBIB RO 1 EB 002346（“数字视网膜成像低成本设备”）的科学研究克里思：NIH宣布恢复法案资金可用于竞争性修订申请。我们正在改进我们的低成本激光扫描数码相机（LSDC）的新颖设计，用于糖尿病视网膜病变筛查而无需瞳孔扩张，通过在我们的聚焦状态上添加电机和传感器，这将提供自动聚焦的潜力，这将有助于经验不足的操作员。降低操作者的成本在装置的每次使用成本中是重要的，从而允许以更具成本效益的方式完成筛选。为了达到服务不足，LSDC不需要瞳孔扩张，但提供了一个高对比度，数字图像。LSDC的设计适用于小瞳孔和舒适的光线水平，产生连续图像，以帮助操作员进行数据采集。近红外照明的使用在所有眼睛颜色中提供了这种高对比度，使得具有深色眼睛的少数受试者仍然容易在舒适的光水平下成像。所提出的新的自动对焦功能自动增加了LSDC作为自动验光仪、白内障检测设备和视网膜地形图仪以客观方式检测黄斑水肿的潜力。我们将在各种屈光不正和眼睛颜色的受试者、白内障患者和患有视网膜病变（包括黄斑水肿）的糖尿病患者中测试和优化该设备。我们将与年龄匹配和性别匹配的正常对照组进行比较。我们还将比较新技术与高端器械（如IOL Master、谱域OCT和波前像差）的结果。我们的主要目标是为所有种族的患者提供高对比度的视网膜图像，包括老年患者，以检测糖尿病视网膜病变。增加的功能带来更高的能效，因为一台仪器可以完成多项功能，节省了功耗、部件数量、占地面积和患者椅时间。该仪器产生的数据还将提供丰富的信息，用于培训学生。 公共卫生相关性：我们将改进我们的低成本视网膜成像设备，激光扫描数码相机，以研究一种低成本的方法来提高操作者的焦点，测量屈光，研究眼睛形状，量化白内障，并量化黄斑水肿的严重程度。一旦开发出来，增加功能只需要最小的增加成本，通过将功能组合到单个设备中来提供能源效率。