Multiwavelength Optical Coherent Endoscopic Oximeter

描述（由申请人提供）： 通过在传统内镜中引入新功能，可以克服内镜在缺血性结肠炎和其他胃肠道疾病早期诊断中的局限性。这些功能允许非侵入性地测量血流和血氧。为了实现这些选择，物理光学公司（POC）提出了一种创新的多波长，光学相干内窥镜血氧计（MENDOXIM）。它将能够测量组织横截面的组织氧合，深度为1-3 mm，横向宽度约为1 mm，同时提供相同区域的高分辨率形态图像。在第一阶段，POC将在组织模型上测试原型MENDOXIM，并在实验室条件下在鸡胚上展示其性能。在评估测试结果后，POC将优化MENDOXIM设计，以开发第二阶段工作原型，为动物模型测试做好准备。

DESCRIPTION (provided by applicant): The limitations of endoscopy for early diagnosis of ischemic colitis and other gastrointestinal diseases can be overcome by introducing new functions into the conventional endoscope. These functions allow noninvasively measuring blood flow and blood-oxygenation. To realize these options Physical Optics Corporate on (POC) proposes an innovative multiwavelength, optical coherence endoscope oximeter (MENDOXIM). It will be capable of measuring tissue oxygenation for tissue cross section to a depth of 1-3 mm with lateral width about 1 mm while providing a high-resolution morphological image of the same area. In Phase I, POC will test the prototype MENDOXIM on tissue phantoms and demonstrate its performance on a chicken embryo in laboratory conditions. Upon evaluation of the test results, POC will optimize the MENDOXIM design for developing a Phase II working prototype ready for tests on animal models.