Self-Caliberating Diagnostic Digital Radiometer

描述（由申请人提供）：拟议计划的总体目标是开发，制造和临床测试一种易于使用的负担得起的诊断仪器，该仪器可以非侵入性地检测地下炎症并估计这种炎症的温度。该仪器的设计将基于一种新型的快速读取，自校准，双频数字辐射计开发下的SBIR赠款从美国国立卫生研究院用于二维eonformal热疗阵列天线。利用微波器件微型化的最新进展，辐射计的前端将与接收天线集成在一起。这将简化辐射计电路，提高其灵敏度，并减少校准和采集时间。检查健康专业人员将能够以与移动听诊器相同的容易性将小型集成天线组件（Thermoscope）移动到患者身体上的任何点，并且快速且准确地确定皮肤温度和在两个不同组织深度上平均的两个皮下组织温度。拟议的第一阶段计划的具体目标是设计，制造和测试一个实验模型的Thermoseope配备自校准诊断双频数字微波辐射计和编写软件的辐射计，这将提高其诊断有用性。

DESCRIPTION (provided by applicant):The overall aim of the proposed program is to develop, fabricate and clinically test an easy-to-use affordable diagnostic instrument that can non-invasively detect subsurface inflammations and estimate the temperatures of such inflammations. The design of this instrument will be based on a novel fast-reading, self-calibrating, dual-frequency digital radiometer developed under an SBIR grant from NIH for use in two-dimensional eonformal hyperthermia array antennas. By taking advantage of recent advances in micro-miniaturization of microwave devices, the front-end of the radiometer will be integrated with the receiving antenna. This will simplify the radiometer circuitry, increase its sensitivity, and reduce calibration and acquisition times. The examining health professional will be able to move the small, integrated antenna assembly (Thermoscope) to any point on the body of a patient with the same ease as moving a stethoscope and quickly and accurately determine skin temperatures and two subsurface tissue temperatures averaged over two different tissue depth. The specific aims of the proposed Phase I program are to design, fabricate and test an experimental model of a Thermoseope equipped self-calibrating diagnostic dual-frequency digital microwave radiometer and write software for the radiometer that will enhance its diagnostic uefulness.