PREDOCTORAL TRAINING PROGRAM IN THE NEUROSCIENCES

描述（改编自申请人提供的摘要）： 神经系统功能，由遗传异常，创伤，疾病或 老龄化对公众健康和生活质量产生巨大影响。 此外，随着美国人数量的大幅增加， 老年痴呆症的认知障碍会 将在未来几十年成为公共卫生的主要负担。最后，最近 人类遗传学的进步，强大的新成像技术，以及 “功能基因组学”的联合收割机结合起来，使这一时期特别迅速 神经科学的进步。培训计划将提供2 博士前研究员在每一个研究的头2年与广泛的 背景和深入的研究培训，他们需要作出重大贡献 神经科学研究的重要性。迫切需要 建议的培训计划，由于1） 在迈阿密大学的神经科学研究实力和 我们申请人的实力和规模，以及2）资金的可用性， 利用这一优势，培养优秀的青年科研人才。的 项目主任J. Bixby博士是轴突生长领域的专家， 突触的形成，也是一个经验丰富的程序管理员和毕业生 学生导师该计划的教师，谁是从基础科学和 临床部门，是一个杰出的，资金充足的科学家群体， 教师的研究兴趣包括一个现代的横截面 神经科学研究课题，谁是研究生教育的领导者证明。 已经有一批优秀的受训候选人;人数 这些高素质的申请人正在增加。的总体目标 该计划旨在指导学员完成获得研究成果的过程 成为独立的神经科学家所需的技能和智力的严谨性。 该计划通过课程，研讨会和期刊实现这些目标 俱乐部，基于研究的资格考试和其他计划活动。的 项目管理部门采用了严格的标准， 学员，教师和计划本身。总而言之， 建议的培训计划包括：1）研究生产力，研究 资金、培训经验和经证明的行政能力， 课程教师一般和程序主任特别是，2） 当前神经科学学生的强大资历和 申请人库，以及3）利用和建立在 现有的神经科学计划提供一流的培训计划， 神经科学

DESCRIPTION (Adapted From The Abstract Provided By Applicant): Disorders of nervous system function, caused by genetic abnormalities, trauma, disease, or aging, have an enormous impact on public health and quality of life. Additionally, with the enormous projected increase in the number of Americans surviving to old age, the cognitive disorders of Alzheimer's Disease will become a major public health burden in the next few decades. Finally, recent advances in human genetics, powerful new imaging techniques, and the emergence of "functional genomics" combine to make this a time for particularly rapid progress in neuroscience. The proposed training program will provide 2 pre-doctoral fellows in each of the first 2 years of study with the broad background and in-depth research training they need to make major contributions to neuroscience research in the coming decades. There is a compelling need for the proposed Training Program, due to the clear mismatch between 1) the strength in neuroscience research within the University of Miami and the strength and size of our applicant pool, and 2) the availability of funds to take advantage of this strength to train outstanding young researchers. The Program Director, Dr. J. Bixby, is an expert in the area of axon growth and synapse formation, and also an experienced program administrator and graduate student mentor. The Program Faculty, who are drawn from both basic science and clinical departments, are an outstanding, well-funded group of scientists and teachers whose research interests comprise a cross-section of modern neuroscience research topics, and who are proven leaders in graduate education. There is already an excellent pool of trainee candidates available; the numbers of these highly-qualified applicants are increasing. The overall aim of the program is to guide the trainees through the process of acquiring the research skills and the intellectual rigor needed to become independent neuroscientists. The Program achieves these goals through coursework, seminars and journal clubs, a research-based qualifying exam, and other program activities. The Program administration has adopted stringent criteria for the evaluation of trainees, faculty, and the Program itself. In summary, major strengths of the proposed Training Program include: 1) the research productivity, research funding, training experience, and proven administrative capability of the Program Faculty in general and the Program Director in particular, 2) the strong credentials of the current neuroscience students and the strength of the applicant pool, and 3) the opportunity to take advantage of and build upon the existing Neuroscience Program to offer a first-class training program in neuroscience.