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中文摘要
翻译
新型培养方法的系统应用现在提供了一个开发大型癌症模型库的机会,可以作为学术界和生物制药行业研究人员的社区资源。为了应对这一机遇,美国国家癌症研究所(NCI)癌症基因组学办公室(OCG)在癌症基因组学中心(CCG)与国际机构一起建立了一个联盟,即人类癌症模型倡议(HCMI)。HCMI的目标是向科学界提供大量“下一代”体外癌症模型,这些模型不会受到过多知识产权(IP)限制的阻碍。为了支持美国对HCMI的贡献,OCG建立了四个癌症模型开发中心(CMDCs)。HCMI的其他创始合作者是英国癌症研究所(CRUK),威康信托桑格研究所(WTSI)和Hubrecht类器官技术基金会(HUB)。
英文摘要
Systematic application of novel culture methods now presents an opportunity to develop a large library of cancer models that can be made available as a community resource to investigators in academia and the biopharmaceutical industry. In response to the opportunity, the National Cancer Institute’s (NCI) Office of Cancer Genomics (OCG), in the Center for Cancer Genomics (CCG), together with international institutions, has established a consortium, the Human Cancer Models Initiative (HCMI). HCMI’s goal is to make available to the scientific community large numbers of “next generation” in vitro cancer models that are not encumbered with excessive intellectual property (IP) constraints. To support the US contribution to HCMI, OCG established four Cancer Model Development Centers (CMDCs). The other founding HCMI collaborators are Cancer Research UK (CRUK), Wellcome Trust Sanger Institute (WTSI), and the Hubrecht Organoid Technology foundation (HUB).
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DCP - Pilot - Biomarker Reference Laboratory
  • 批准号:
    10282237
  • 项目类别:
  • 资助金额:
    $15.0万
  • 财政年份:
    2020
  • 负责人:
    LEONARD FREEDMAN
  • 依托单位:
DCP - Clinical Trials Regulatory & Monitoring Support for US-Latin American-Caribbean HIV/HPV-Cancer Prevention Clinical Trials Network
  • 批准号:
    10282236
  • 项目类别:
  • 资助金额:
    $50.0万
  • 财政年份:
    2020
  • 负责人:
    LEONARD FREEDMAN
  • 依托单位:
DCP - Biopharmaceutical Development Program (BDP) Support
  • 批准号:
    10282235
  • 项目类别:
  • 资助金额:
    $100.0万
  • 财政年份:
    2020
  • 负责人:
    LEONARD FREEDMAN
  • 依托单位:
DCEG- Repository Services for epidemiology studies
  • 批准号:
    10273214
  • 项目类别:
  • 资助金额:
    $275.03万
  • 财政年份:
    2020
  • 负责人:
    LEONARD FREEDMAN
  • 依托单位:
海外基金