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Measuring Hearing in Children with Developmental Differences

测量有发育差异的儿童的听力

基本信息

批准号：
10757571
负责人：
Angela Yarnell Bonino
金额：
$ 13.16万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-04-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10757571
关键词：
Measuring Hearing Children Developmental Differences

项目摘要

Nearly 40% of children with hearing loss have a secondary disability, yet audiologists lack the appropriate behavioral assessment procedures to measure hearing in children with diverse or complex developmental profiles. The long-term goal of this line of research is to improve hearing health care for children with developmental disabilities by transforming behavioral hearing testing methods. The overall objectives for this application are to identify gaps in current clinical care and to isolate methodological and child factors that affect behavioral data. Our central hypothesis is that the inability to obtain accurate and reliable behavioral thresholds with current behavioral procedures reflects methodology limitations, not limitations of the child. The rationale for this work is that by isolating factors that affect threshold we can develop rigorous methods that overcome the limitations of current clinical practices; thereby, improving hearing health care for children with developmental disabilities. The central hypothesis will be tested by pursuing two specific aims: (1)!identify gaps in the current state of clinical assessment practices for children with developmental disabilities; and (2) identify factors that influence behavioral threshold accuracy. Under the first aim, big data analytics with a publicly-available database will be used to assess the current clinical situation. For the second aim, using a novel observer-based psychoacoustics procedure, we will evaluate methodological and child factors that are expected to affect behavioral data from 1.5- to 5-year-old children with different developmental status (Autism Spectrum Disorder, Down syndrome, or typical development). The research proposed in this application is innovative, in the applicant’s opinion, because it (1) harnesses the power of big data analytics to accelerate the pace of research in pediatric audiology, and (2) it uses an observer-based procedure that overcomes the challenges associated with collecting and interpreting data from children with developmental disabilities. The proposed work is significant because it will provide strong scientific evidence for modifying current clinical procedures for children with developmental disabilities and for developing much-needed methodology advancements essential to eliminating existing hearing health care disparities.!

近 40% 的听力损失儿童有继发性残疾，但听力学家缺乏适当的治疗方法行为评估程序，用于测量具有多样化或复杂发育的儿童的听力配置文件。该研究的长期目标是改善患有听力障碍的儿童的听力保健通过改变行为听力测试方法来解决发育障碍。本次活动的总体目标应用程序的目的是确定当前临床护理中的差距，并隔离影响的方法论和儿童因素行为数据。我们的中心假设是无法获得准确可靠的行为阈值当前的行为程序反映了方法的局限性，而不是儿童的局限性。理由这项工作是通过隔离影响阈值的因素，我们可以开发严格的方法来克服当前临床实践的局限性；从而改善发育障碍儿童的听力保健残疾。中心假设将通过追求两个具体目标来检验：（1）！找出当前的差距发育障碍儿童的临床评估实践状况； (2) 确定因素影响行为阈值准确性。第一个目标是利用公开数据库进行大数据分析将用于评估当前的临床情况。对于第二个目标，使用一种新颖的基于观察者的心理声学程序，我们将评估预计影响的方法论和儿童因素 1.5岁至5岁不同发育状态儿童的行为数据（自闭症谱系障碍、唐氏综合症，或典型发育）。本申请提出的研究具有创新性，申请人的意见，因为它（1）利用大数据分析的力量来加快研究步伐在儿科听力学中，（2）它使用基于观察者的程序来克服相关的挑战收集和解释来自发育障碍儿童的数据。拟议的工作是意义重大，因为它将为修改当前儿童临床程序提供强有力的科学证据对于发育障碍和开发急需的方法进步至关重要消除现有的听力保健差距。！