Duke-UNC Clinical Hematology Research Career Development Program

杜克大学-北卡罗来纳大学临床血液学研究职业发展计划

• 批准号: 7292679
• 负责人: Marilyn J Telen
• 金额: $ 39.82万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-28 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7292679
• 关键词: Academic Medical Centers; Area; Basic Science; Benign; Blood; Clinical; Clinical Research; Clinical Trials; Commit; Educational Curriculum; Educational process of instructing; Ensure; Extramural Activities; Faculty; Fruit; Funding; Genetic; Genomics; Goals; Health Policy; Heart; Hematology; Hemoglobinopathies; Hemostatic function; Institutes; Lead; Lung; Master' s Degree; Mediation; Medical; Medical center; Mentored Clinical Scientist Development Program; Mentors; NCI Scholars Program; Non-Malignant; North Carolina; Outcome; Pharmacogenetics; Program Development; Purpose; Range; Research; Research Personnel; Research Training; Thrombosis; Training; Translating; Translational Research; Universities; career; design; experience; multidisciplinary; patient oriented research; programs; response; skills

DESCRIPTION (provided by applicant): Duke University Medical Center (DUMC) and the University of North Carolina at Chapel Hill jointly propose a Clinical Hematology Research Career Development Program (K12 CHRCDP) in response to the National Heart, Lung and Blood Institute RFA-HL-06-006. Duke and UNC have long traditions of collaborative basic and clinical research in non-malignant hematology. We now propose to establish a program to train scholars in clinical research in areas of non-malignant hematology that are well established strengths of our medical center, namely hemoglobinopathies, hemostasis and thrombosis and trasnsfusion. The purpose of the present application is therefore to ensure high quality patient-oriented research training at Duke and UNC through the provision of a clinical, didactic and experiential program for scholars who are committed to academic clinical research careers focusing on benign hematology. This CHRCDP will include a didactic and clinical curriculum designed to teach scholars the broad array of skills needed to perform clinical research and to establish successful academic research careers in nonmalignant hematology. Each scholar will have the opportunity to earn a master's degree in either clinical research or in medical genomics. In addition, we propose four primary research tracks that our trainees can enter for their mentored research experience in non-malignant hematology. Each has at least two Lead Mentors, and there are numerous faculty at Duke and UNC who will serve as secondary mentors. Our 4 tracks are (1) Translational Research, (2) Genetics and Pharmacogenetics; (3) Clinical Trials; and (4) Outcomes/Health Policy. This combination of clinical and didactic training and a mentored research experience will prepare scholars for submission of applications for extramural funding for their ongoing research program and for successful negotiation of their research careers. The long-range goal of this program is thereby to help ensure an adequate supply of well trained researchers who will be able to confront the clinical problems of non-malignant hematology through well-designed, skillfully conducted and multidisciplinary clinical research and who will be skilled in translating the fruits of basic research into clinical practice.

描述（由申请人提供）： 杜克大学医学中心 (DUMC) 和北卡罗来纳大学教堂山分校联合提出临床血液学研究职业发展计划 (K12 CHRCDP)，以响应国家心肺和血液研究所 RFA-HL-06-006。杜克大学和北卡罗来纳大学在非恶性血液学方面有着长期合作基础和临床研究的传统。我们现在提议建立一个项目，培训非恶性血液学领域临床研究的学者，这些领域是我们医疗中心的既定优势，即血红蛋白病、止血、血栓形成和输血。因此，本申请的目的是通过为致力于良性血液学学术临床研究职业的学者提供临床、教学和体验计划，确保杜克大学和北卡罗来纳大学提供高质量的以患者为导向的研究培训。 该 CHRCDP 将包括教学和临床课程，旨在向学者传授进行临床研究和在非恶性血液学领域建立成功的学术研究职业所需的广泛技能。每位学者将有机会获得临床研究或医学基因组学硕士学位。此外，我们建议学员可以进入四个主要研究方向，以获得他们在非恶性血液学方面的指导研究经验。每个导师都至少有两名首席导师，杜克大学和北卡罗来纳大学有许多教师将担任二级导师。我们的 4 个方向是 (1) 转化研究，(2) 遗传学和药物遗传学； (3) 临床试验； (4) 结果/健康政策。这种临床和教学培训以及指导研究经验的结合将使学者们为他们正在进行的研究项目提交校外资助申请以及成功谈判他们的研究生涯做好准备。因此，该计划的长期目标是帮助确保提供足够的训练有素的研究人员，他们将能够通过精心设计、熟练实施和多学科临床研究来应对非恶性血液学的临床问题，并熟练地将基础研究成果转化为临床实践。